
Lake house vacation rentals in Seneca
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in Seneca
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca lake house rentals
Waterfront lakehouse rentals

Lake Keowee Beach Club Cabin

New Waterfront House with Big Views & Private Dock

Lakefront Keowee Luxury Cottages 127

Lake Home & Treehouse ❤ Seneca Treehouse Project

Anchor Point, Lake Retreat - Clemson, 2-story dock

Lake Keowee SC Lakehouse Escape

Keowee’s family house with hot tub, kayaks, & more

Clemson ,Lake Hartwell, Waterfront, pontoon rental
Pet-friendly lake house rentals

Sunset Point-Best view on Broadway - HOT TUB!

Lakefront luxury home w/panoramic view & Boat Slip

Lake house waterfront, 10 min to downtown w Kayaks

Keowee Lakeside with pool for 16

A Travelers Nest ~ Lake House

Havenly Lake House w/ Hot Tub & Private Dock!

The Tiny Pickleball Mansion at Lake Hartwell

Lakefront with wooded lot and great views
Private lake house rentals

Preachers Paradise on Lake Hartwell

Clear View Cottage

Good Times @ Clemson / Lake Hartwell

Lake House Retreat Near Clemson

Dock-Boat Lift-Kayaks-Firepit-Screened Patio-Grill

Insta-Worthy Lakefront Home w/ Dock + Fire Pit

On Hartwell, Private Boat Dock, Near Boat Launch

Golf view, lake access, 3 pools!
Destinations to explore
- Western North Carolina Vacation rentals
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- North Myrtle Beach Vacation rentals
- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
- Helen Tubing & Waterpark
- Mountaintop Golf & Lake Club
- Table Rock State Park
- Tallulah Gorge State Park
- Bell Mountain
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Don Carter State Park
- Victoria Bryant State Park
- Funopolis Family Fun Center
- Old Edwards Club
- Anna Ruby Falls
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Louing Creek
- Chattooga Belle Farm
- Wellborn Winery
- City Scape Winery