Vacation rentals in Seneca

Find and book unique accommodations on Airbnb

Quick stats about vacation rentals in Seneca

  • Total vacation rentals

    Explore 70 vacation rentals in Seneca

  • Nightly prices starting at

    Seneca vacation rentals start at €43 per night before taxes and fees

  • Verified guest reviews

    Over 2,550 verified reviews to help you choose

  • Family-friendly vacation rentals

    50 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    70 of Seneca vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across Seneca rentals

  • 4.9 Average rating

    Seneca stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated vacation rentals in Seneca

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A serene view of the cove showcases calm blue waters bordered by lush greenery and trees. Several boats are docked at a wooden pier, with homes visible along the shoreline. Fluffy clouds drift in a clear blue sky above this tranquil scene.
Home in Seneca
4.85 out of 5 average rating, 88 reviews

Peaceful Lake Keowee Waterfront Home ~Near Clemson

Live out your lake dreams at this 3/3 conveniently located 5 minutes to downtown Seneca!! Swim in the beautiful Keowee water right off private dock with direct access from backyard. Bring your boat or explore Lake Keowee in 2 available kayaks. Enjoy outdoor dining on the deck overlooking the lake, cooking in the open kitchen, grilling out in the backyard, or enjoying the fire pit. Separate downstairs suite with private access. Only 7 miles from Clemson and down the street from the Keowee Marina

Top guest favorite
Home in Seneca
4.98 out of 5 average rating, 63 reviews

Johnsons Cove - Lakefront Retreat With EV Charger

Welcome to Johnsons Cove - Lakeside Retreat! With over 400 feet of deep water, private lake frontage. This home comes equipped with a full-sized dock, four kayaks (see Adtl Rules), and a lily pad. Life vests are supplied in a variety of sizes for your safety. A unique boat ramp is on the property only for non-motorized watercrafts. There is a small sandy beach for easy access to walk into the lake. This quiet cove is perfect for swimming around the dock. Don't miss out on this special location!

Top guest favorite
The image showcases a serene lakefront view featuring a newly renovated cottage framed by lush greenery. A wooden dock extends into the calm water, providing a peaceful area to relax. The cottage's warm exterior is complemented by the surrounding trees, enhancing the natural setting.
Home in Seneca
5.0 out of 5 average rating, 133 reviews

Modern Lake Vibes – Kayaks, Dock & Fireplace

The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Top guest favorite
Home in Seneca
4.95 out of 5 average rating, 143 reviews

Hanover Haven 3 BR/2 Bath

Hanover Haven is located close to all you need! Clemson University is only 3 miles away. There are 3 full grocery stores within 5 minutes. Lake Keowee access and marina all within 5 miles. The Gathering space is such a great place to have family fun! There are card games and large TVs with multiple streaming platforms. We are also working on a great outdoor space that will include a grill and sail shade ready for the summer. There is also an RV on the property that is an AirBNB with privacy.

Top guest favorite
A custom-built cottage is nestled in a natural setting, surrounded by greenery. The structure features warm lighting emanating from windows, complemented by a spacious porch. The surrounding lawn offers ample space, framed by trees that enhance the peaceful atmosphere.
Cabin in Seneca
4.99 out of 5 average rating, 95 reviews

Cottage in the Country w/ Hot Tub/12mi to Clemson

Relax and unwind at our custom built cottage that provides a peaceful space perfect for 2. This cozy retreat is nestled in the woods in a country setting and offers a deck and hot tub to enjoy the beauty of nature. A dedicated work space is also provided if you're here for work or looking for a place for solitude. It's located only 5 miles from Seneca, 12 miles from Clemson, and 40 miles from Greenville and is a short drive as well to beautiful lakes, waterfalls, and hiking trails.

Guest favorite
Home in Seneca
4.97 out of 5 average rating, 31 reviews

Lakefront Home w/Deep Water Dock 20 min to Clemson

Welcome to the King of Harts! Our 4 BR/2BA home on Lake Hartwell has a deep water, covered dock with electricity that is only 20 minutes to Clemson, 15 minutes to Seneca, and less than 1 hour from many amazing waterfalls and hiking trails in the blue ridge. Two kayaks included for exploring the cove! The house has been updated with cozy furnishings, fast wi-fi, and a 70 inch TV in the living room so can feel like you're at the game when you're actually just steps away from the lake!

Superhost
A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.
Home in Seneca
4.99 out of 5 average rating, 234 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

Guest favorite
A spacious sunken living area features a large brick fireplace as a central focal point, flanked by two inviting seating arrangements. Natural wood beams extend across the ceiling, and light fills the space through multiple large windows, creating a warm and welcoming environment.
Home in Seneca
4.94 out of 5 average rating, 78 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Guest favorite
The bedroom features a spacious bed with plush pillows and a textured bedspread. A stylish chandelier illuminates the room, complemented by natural light from two large windows. Decorative wall accents and a soft area rug enhance the inviting atmosphere.
Cabin in Seneca
4.89 out of 5 average rating, 175 reviews

Clemson- 5 Min | Hot Tub | Game Room | 5 King Beds

5 minutes to Clemson University & Lake Keowee with a private saltwater hot tub, full arcade-style game room and stocked bar—perfect for families or game-day groups! 4 spacious bedrooms, 7 total beds High-speed Wi-Fi & smart TVs in every room Outdoor deck with grill, fire-pit & cornhole Fully equipped kitchen + coffee bar Rated 4.9★ by 171 guests and hosted by a local husband/wife team who lives nearby for quick help. Book your Clemson retreat today—dates fill fast!

Superhost
A charming cabin is nestled among trees, featuring a sloped roof and front porch. Two green chairs are placed on a sandy pathway leading to the entrance, inviting relaxation in a serene outdoor setting.
Tiny home in Seneca
4.98 out of 5 average rating, 117 reviews

Oak Hill Getaway

Right between Seneca and Clemson you will find our getaway. It's 5 mins from Historic Ram Cat Alley with shopping, restaurants, and breweries with Jazz on the Alley music every Thursday night (April - Oct.) It's only 10 minutes from Clemson University. Surrounded by 3 different lakes Jocassee, Keowee, and Hartwell with just a short drive away. You can ride 30 mins up to the mountains where you can hike trails and see waterfalls the foothills have to offer.

Top guest favorite
A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.
Home in Seneca
5.0 out of 5 average rating, 140 reviews

The Cottage

Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Top guest favorite
The exterior of a modern tiny house is depicted, featuring a dark blue façade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.
Cottage in Westminster
4.98 out of 5 average rating, 672 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Popular amenities for Seneca vacation rentals

When is the best time to visit Seneca?

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Avg. price€128€154€143€142€184€208€160€201€193€166€193€154
Avg. temp6°C8°C12°C16°C21°C25°C27°C26°C23°C17°C11°C7°C

Frequently Asked Questions

  • What are the best places to stay in Seneca?

    Travelers often stay near Lake Keowee for access to water activities, Historic Downtown for local shops and restaurants, or in the countryside for a quieter experience. Many homes and apartments in these areas welcome visitors looking for both relaxation and recreation.

  • What are the best things to do in Seneca with kids?

    Families can explore local parks, visit playgrounds, or enjoy time by Lake Keowee for swimming and picnics. Educational centers, walking trails, and family-friendly events around town are also frequently suggested.

  • What are some of the best things to do in Seneca?

    Explore Historic Downtown’s boutiques and cafes, relax at Lake Keowee, or visit nearby state parks for hiking and outdoor recreation. Community festivals and farmers markets also add a local touch throughout the year.

  • How is the weather in Seneca?

    Seneca has mild winters around 33–53°F (1–12°C) and warm, humid summers that reach 90°F (32°C). Rain is spread throughout the year, so it is helpful to bring layers and a rain jacket for outdoor plans.

  • When is the best time to visit Seneca?

    Late spring and early autumn are often recommended for comfortable temperatures and colorful scenery. Summer is popular for lake activities, while spring brings local events and blooming landscapes.

  • What are the best places to visit in Seneca?

    Explore Lake Keowee’s shores, browse Historic Downtown’s local shops, or head to South Cove County Park for picnic spots and waterfront access. Cultural centers and museums around town are also frequently suggested.

  • What are some hiking trails in Seneca?

    You will find walking and hiking paths in South Cove County Park and around Lake Keowee. For more variety, nearby state parks are known for scenic trails suitable for most experience levels.

  • What are some family activities we can do in Seneca?

    Families can picnic at local parks, swim or paddle on Lake Keowee, and explore interactive exhibits in community centers. Seasonal festivals and farmers markets often host games, music, and family-friendly vendors.

  • What are some of the best day trip ideas from Seneca?

    Visitors frequently explore nearby state parks for hiking and waterfalls, check out upstate art towns, or tour local vineyards and orchards. Lakes, historic sites, and mountain views are also within easy reach for a full day’s adventure.

  • Are there any pet friendly accommodations available in Seneca?

    Many places in and around Seneca welcome pets, especially those near Lake Keowee or set in rural surroundings. It is helpful to check individual listings for rules on pets and any special amenities, such as fenced yards or easy trail access.

  • What are some local tips for visiting Seneca?

    Try the weekly farmers market for local produce and crafts, and enjoy the lake early or late in the day for quieter moments. Locals appreciate layered clothing due to changing weather and recommend checking for community events during your stay.

  • What is Seneca known for?

    Seneca has a lively lakeside community centered around Lake Keowee, a revitalized Historic Downtown, and access to outdoor recreation in the foothills of the Blue Ridge Mountains. Community events and historic sites reflect the area’s local traditions.

  • What are the best hidden gems to explore in Seneca?

    Many visitors enjoy lesser-known parks, local art galleries, and specialty shops tucked away in Historic Downtown. Quiet coves along Lake Keowee and nearby heritage museums also draw those seeking unique local experiences.

  • What are the best foods to try in Seneca?

    Seneca has locally rooted Southern cuisine, with dishes like barbecue, fried catfish, and homemade pies often recommended. Seasonal farmers markets around the area feature regional produce and handmade treats during parts of the year.

  • What should I bring for a trip to Seneca?

    Pack layers for changing temperatures, a rain jacket for unexpected showers, and comfortable shoes for outdoor activities. A swimsuit, sun protection, and reusable water bottle are helpful for time by the lakeshore or on trails.

  • What is the nightlife in Seneca like?

    Seneca’s nightlife features casual bars, local pubs, and live music venues around Historic Downtown. Events and open-air concerts bring residents and visitors together during warmer months.

  • What are the most popular events or festivals in Seneca?

    Seneca hosts seasonal festivals, including downtown music events, local fairs, and outdoor concerts, especially in the warmer months. Community celebrations around Memorial Day and late spring are frequently highlighted by locals.

  • Are there family friendly vacation rentals in Seneca?

    Seneca has a range of family-friendly rentals, including lakefront homes and properties in quiet residential neighborhoods. Many include amenities such as full kitchens, multiple bedrooms, and outdoor spaces for children to play.