
Vacation rentals with lake access in Seneca
Find and book unique lake access rentals on Airbnb
Quick stats about vacation rentals with lake access in Seneca

Total vacation rentals
Explore 20 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at €111 per night before taxes and fees

Verified guest reviews
Over 610 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated lake access rentals in Seneca
Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Hartwell Hideway
Escape to this cozy 1-bedroom, 1-bath apartment perched above a private garage on Lake Hartwell. It's just 15 minutes from Clemson University and quaint downtown Seneca. With a full kitchen, cozy living space, on-site parking, keyless entry, and owners nearby, you’ll have everything you need for a relaxing visit. ✔ New build 2024 ✔ Boat access 5 minutes away ✔ Hiking & waterfalls nearby Whether you're here for a Clemson game, a lake adventure, or a quiet getaway, this is the perfect home base.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Little Blue Lake House | Minutes from CU
Welcome to Little Blue Lake House! Wake up to stunning lake views right across the water from Clemson University and Death Valley Stadium! This cozy 2-bedroom tiny home (1 private br, 1 loft) is the perfect retreat for couples or small families looking for a getaway with unbeatable location. - Directly across the lake from CU & Death Valley Stadium (8 min drive) - 3 min from Clemson Marina - Close to hiking trails, waterfalls, and outdoor adventures - 45 minutes to Greenville’s downtown

Clemson Games + Lake Keowee
Come stay at this new construction home in a Lake Keowee neighborhood, only 8 miles from Clemson and to Death Valley. Whether you're seeking convenient access to Clemson for college activities, such as move-in move out for students, game weekends, or to enjoy Lake Keowee this house is the perfect fit! This house offers plenty of amenities during your stay such as blackout curtains in all the bedrooms, a privacy fence in the backyard for barbecuing, and a ping-pong table in the garage! 

Lakefront Mid-Century Dream Home / 3 mi to Clemson
We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Holliday's Inn Tiny Tree-house
Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Lake Keowee Cabin: Peaceful and Bright
Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

5 Min to Clemson | Hot Tub | Game Room | 5 Kings
5 minutes to Clemson University & Lake Keowee with a private saltwater hot tub, full arcade-style game room and stocked bar—perfect for families or game-day groups! 4 spacious bedrooms, 7 total beds High-speed Wi-Fi & smart TVs in every room Outdoor deck with grill, fire-pit & cornhole Fully equipped kitchen + coffee bar Rated 4.9★ by 171 guests and hosted by a local husband/wife team who lives nearby for quick help. Book your Clemson retreat today—dates fill fast!
Popular amenities for Seneca lake access rentals
Lake access house rentals

Lake Hartwell house w/ dock 2 miles from Clemson.

Dujardins Keowee Waterfront Home

Lake Keowee Home-It's like being in a tree house.

Lakeside Retreat • Pet friendly • Fire Pit

Keowee Key Luxury Condo - Stunning Views!

Peaceful Lake Keowee Waterfront Home ~Near Clemson

The Landing Spot

Johnsons Cove - Lakefront Retreat With EV Charger
Lake access apartment rentals

Lake Hartwell - Hartwell Villa 8A

3BR Ground floor condo - 2.4 Miles to Death Valley

Condo at Lake Keowee

Quiet, Cozy Condo in Keowee Key

Deane's Dock Holiday Suite, (1 bedroom)

Friendship Lake Apartment

Lakeside Oasis 3BR 2BA Near Clemson, Stocked Lake!

On The DL Apartment/Lake Hartwell/Clemson
Lake access cottage rentals

Waterfront cottage w/deep dock 17 miles to Clemson

Relax at Red Door Cottage and enjoy the view!

A-Frame Lake Hartwell Cottage w/ Hot Tub

Cottage on the Lake

Rare Aug. Dates Open! Sunset Cottage Lake Hartwell

Lakefront cottage with a view, near Clemson

Private Trail into Table Rock

Unwind & Reconnect in Nature|Serenity by the Lake!
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €257 | €225 | €257 | €263 | €351 | €386 | €317 | €327 | €303 | €309 | €317 | €257 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
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- Clemson University
- Table Rock State Park
- Black Rock Mountain State Park
- Gorges State Park
- Helen Tubing & Waterpark
- Tallulah Gorge State Park
- Devils Fork State Park
- Bell Mountain
- DuPont State Forest
- Unicoi State Park and Lodge
- Chattooga Belle Farm
- Bon Secours Wellness Arena
- Jump Off Rock
- Fred W Symmes Chapel
- Fluor Field at the West End
- Jones Gap State Park
- Falls Park On The Reedy
- Peace Center
- Dry Falls
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site
- Whitewater Falls
- Soquee River
- Smithgall Woods State Park





