
Vacation rentals with lake access in Seneca
Find and book unique lake access rentals on Airbnb
Quick stats about vacation rentals with lake access in Seneca

Total vacation rentals
Explore 20 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at €112 per night before taxes and fees

Verified guest reviews
Over 610 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated lake access rentals in Seneca
Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

Lake Hartwell house w/ dock 2 miles from Clemson.
This is a simple, comfortable, recently renovated (2019) home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is 1 cove away. Clemson golf course is across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Peaceful Lake Keowee Waterfront Home ~Near Clemson
Live out your lake dreams at this 3/3 conveniently located 5 minutes to downtown Seneca!! Swim in the beautiful Keowee water right off private dock with direct access from backyard. Bring your boat or explore Lake Keowee in 2 available kayaks. Enjoy outdoor dining on the deck overlooking the lake, cooking in the open kitchen, grilling out in the backyard, or enjoying the fire pit. Separate downstairs suite with private access. Only 7 miles from Clemson and down the street from the Keowee Marina

Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Dujardins Keowee Waterfront Home
2 night min. Deep water lot on Lake Keowee with double dock, and tons of entertaining space. On the main level, the great room/dining room is open to the kitchen. 4 bedrooms total, 3 king bedrooms (2 on first floor), 1 king and a bunk room with 2 doubles and 2 singles. A canoe, 2 paddle boards and 2 double kayaks included. Shuffleboard, foosball, outdoor Ping-Pong, board games and two person pac-man game, with additional 60 games! towels and linens included! Pickleball/tennis 10 min away!

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

House on Lake Keowee swim beach in cove w/ Dock
This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Clemson Lake Hartwell Waterfront, Pontoon Rental
Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

Lake Keowee Cabin: Peaceful and Bright
Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Clemson- 5 Min | Hot Tub | Game Room | 5 King Beds
5 minutes to Clemson University & Lake Keowee with a private saltwater hot tub, full arcade-style game room and stocked bar—perfect for families or game-day groups! 4 spacious bedrooms, 7 total beds High-speed Wi-Fi & smart TVs in every room Outdoor deck with grill, fire-pit & cornhole Fully equipped kitchen + coffee bar Rated 4.9★ by 171 guests and hosted by a local husband/wife team who lives nearby for quick help. Book your Clemson retreat today—dates fill fast!

Lake Keowee, Waterfront Cabin, 2-Story Dock!
Beautiful cabin 15 min from Clemson Stadium. Boasting cathedral ceilings, this home offers an open floor plan for everyone to gather. Sleeping 10 with 4 bedrooms and 3.5 bathrooms and 2 living rooms, there is space for everyone. Steep incline from lake to house with paved stairs. Tram from deck to dock! Fire pit with wood provided. Large deck and covered porch. Large covered dock for your boat with 650 sq. ft. second floor sundeck. 2 car garage. Hot Tub!

Hartwell Escape 6 mi to Clemson Beautiful views
We recently purchased this gorgeous home on Lake Hartwell, in a secluded cul-de-sac in a quiet neighborhood (6 miles to Clemson..ALL BACKROADS) You will have the entire bottom floor with separate entrance . Enjoy beautiful lake views on the covered porch or from our dock. A Private Neighborhood Boat ramp is 25 feet from our home. Bring your boat, use our dock, space for multiple trailers. Driveway parking. Dogs Welcome! ($25 pet fee/entire stay)
Popular amenities for Seneca lake access rentals
Lake access house rentals

Keowee Key Luxury Condo - Stunning Views!

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Johnsons Cove - Lakefront Retreat With EV Charger

Clemson Games + Lake Keowee

Lakefront Private Cove with Boat/Jet Ski Options

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

Near Clemson, Hot Tub, Game Room, Kayaks, Dock

Sweet Tea Retreats
Lake access apartment rentals

Lake Hartwell - Hartwell Villa 8A

3BR Ground floor condo - 2.4 Miles to Death Valley

Condo at Lake Keowee

Quiet, Cozy Condo in Keowee Key

2 Bedroom Suite At Deane's Dock Holiday

Lakefront 3BR 2BA Near Clemson, Stocked Lake!

Waterfront Lake Hartwell Apt w Dock Access!

On The DL Apartment/Lake Hartwell/Clemson
Lake access cottage rentals

Cottage on the Lake

A-Frame Lake Hartwell Cottage w/ Hot Tub

Rare Aug. Dates Open! Sunset Cottage Lake Hartwell

Waterfront cottage w/deep dock 17 miles to Clemson

Lakefront cottage with a view, near Clemson

Lakefront dock *hot tub* Anderson/Clemson king bed

Relax at Red Door Cottage and enjoy the view!

Peace on Earth Townville, SC
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €258 | €226 | €258 | €264 | €352 | €387 | €319 | €328 | €304 | €310 | €319 | €258 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
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- Bell Mountain
- DuPont State Forest
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