
Vacation rentals in Seneca
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Top-rated vacation rentals in Seneca
Guests agree: these stays are highly rated for location, cleanliness, and more.

A-Frame Lake Hartwell Cottage w/ Hot Tub
No lake water till it substantially rains Lake Hartwell cottage w/ Hot Tub ! Clemson 9 mi. away! 2 bdrm, 2 full bath, hot-tub, canoe, 2kayaks, 🎣 poles, life-vests, dining & patio table, grill+charcoal, 3tv, Netflix/2DVDplayers/DVDs, kitchen, pots/pans, 2crockpot, microwave, dishwasher+pods, keurig+coffee, washer+detergent, dryer, spices, shampoo/cond, hair dryer, curler, straightener, linens, towels, 3bikes, helmet, Karaoke, firepit+wood, wall of fun! (Boat-landing 1 mi. away! Cateechee Shores

Hanover Haven 3 BR/2 Bath
Hanover Haven is located close to all you need! Clemson University is only 3 miles away. There are 3 full grocery stores within 5 minutes. Lake Keowee access and marina all within 5 miles. The Gathering space is such a great place to have family fun! There are card games and large TVs with multiple streaming platforms. We are also working on a great outdoor space that will include a grill and sail shade ready for the summer. There is also an RV on the property that is an AirBNB with privacy.

The Wildflower
Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

THE BELLA LUNA Romantic Treehouse - Outdoor Shower
This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Basement apartment in Pendleton w/ sep. entrance
This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

The Romantic Greystone Cottage
Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

The Pendle-Tin
At the Pendle-tin, you’re close to it all, yet feel tucked away in the west end of downtown Pendleton. You’re 5-8 min from Clemson’s Death Valley, and 2 blocks from downtown Pendleton where you’ll find eateries, and shops. About 5 min from the lake and about 45-50 min from the mountains. Inside you’re Equipped with a kitchen, full bath, WiFi, smart tv , queen bed and separate work space . Outside you have seating for 4 and a propane fire pit.

Tiny house
BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.

Windmill Cottage
You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!
Popular amenities for Seneca vacation rentals
Stay near Seneca's top sights
Other great vacation rentals in Seneca

Oak Hill Getaway

Singing Pines Cottage

Adjacent to Dawson Park/1 mile from Clemson Univ

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Treehouse at Keowee Hollow

Cottage w/ Hot Tub, 12 Miles to Clemson

Hartwell Hideway

Destination Keowee
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | € 120 | € 115 | € 119 | € 129 | € 168 | € 139 | € 156 | € 197 | € 189 | € 163 | € 189 | € 150 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Frequently Asked Questions
Where should I stay in Seneca?
Make yourself at home in Seneca by choosing from our most frequently booked neighborhoods. We have over 110 vacation rentals in Utica, and over 180 vacation rentals in Seneca.
Are there vacation rentals with a dedicated workspace in Seneca?
Yes! Work meets play with ease at over 20 vacation rentals in Seneca featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Seneca?
Four-legged friends are welcome in Seneca. Choose from more than 20 vacation rentals for guests traveling with pets.
How much does it cost to stay in house rentals in Seneca?
Experience the best of Seneca with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there family-friendly vacation rentals in Seneca?
Seneca has more than 50 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Seneca have wifi?
Absolutely! We offer over 40 house rentals with wifi in Seneca. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Seneca have air conditioning?
Absolutely! We offer over 40 house rentals with air conditioning in Seneca. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for House Rentals in Seneca?
Enhance your stay in our House Rentals with the most popular amenities: over 40 homes with air conditioning, over 40 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.
Quick stats about vacation rentals in Seneca

Total vacation rentals
Explore 60 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at € 42 per night before taxes and fees

Verified guest reviews
Over 2,400 verified reviews to help you choose

Family-friendly vacation rentals
50 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
60 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Gym, BBQ grill, and Laptop-friendly workspace across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
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- Black Rock Mountain State Park
- Gorges State Park
- Ski Sapphire Valley
- Tallulah Gorge State Park
- Table Rock State Park
- Bell Mountain
- Helen Tubing & Waterpark
- Clemson University
- Jump Off Rock
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site
- Bon Secours Wellness Arena
- Fred W Symmes Chapel
- DuPont State Forest
- Devils Fork State Park
- Smithgall Woods State Park
- Chattooga Belle Farm
- Paris Mountain State Park
- Peace Center
- Falls Park On The Reedy
- Greenville Zoo
- Looking Glass Falls
- Jones Gap State Park
- Unicoi State Park and Lodge




