
Waterfront vacation rentals in Seneca
Find and book unique waterfront rentals on Airbnb
Quick stats about waterfront rentals in Seneca

Total vacation rentals
Explore 10 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at €111 per night before taxes and fees

Verified guest reviews
Over 550 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Wi-Fi availability
10 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated waterfront rentals in Seneca
Guests agree: these waterfront rentals are highly rated for location, cleanliness, and more.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Lake Hartwell house w/ dock 2 miles from Clemson.
This is a simple, comfortable, recently renovated (2019) home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is 1 cove away. Clemson golf course is across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Peaceful Lake Keowee Waterfront Home ~Near Clemson
Live out your lake dreams at this 3/3 conveniently located 5 minutes to downtown Seneca!! Swim in the beautiful Keowee water right off private dock with direct access from backyard. Bring your boat or explore Lake Keowee in 2 available kayaks. Enjoy outdoor dining on the deck overlooking the lake, cooking in the open kitchen, grilling out in the backyard, or enjoying the fire pit. Separate downstairs suite with private access. Only 7 miles from Clemson and down the street from the Keowee Marina

Hartwell Hideway
Escape to this cozy 1-bedroom, 1-bath apartment perched above a private garage on Lake Hartwell. It's just 15 minutes from Clemson University and quaint downtown Seneca. With a full kitchen, cozy living space, on-site parking, keyless entry, and owners nearby, you’ll have everything you need for a relaxing visit. ✔ New build 2024 ✔ Boat access 5 minutes away ✔ Hiking & waterfalls nearby Whether you're here for a Clemson game, a lake adventure, or a quiet getaway, this is the perfect home base.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Little Blue Lake House | Minutes from CU
Welcome to Little Blue Lake House! Wake up to stunning lake views right across the water from Clemson University and Death Valley Stadium! This cozy 2-bedroom tiny home (1 private br, 1 loft) is the perfect retreat for couples or small families looking for a getaway with unbeatable location. - Directly across the lake from CU & Death Valley Stadium (8 min drive) - 3 min from Clemson Marina - Close to hiking trails, waterfalls, and outdoor adventures - 45 minutes to Greenville’s downtown

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Lakefront Mid-Century Dream Home / 3 mi to Clemson
We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Hidden Cove Cottage - With Lake Access
BRAND NEW!! Hidden Cove Cottage is a quiet lakeside getaway tucked into a private wooded cove. The cabin features two private bedrooms, each with a queen bed, a comfortable living space with a queen sleeper sofa, and a spacious deck overlooking the water. Outside, enjoy the BBQ grill, fire pit, and easy shoreline access. Peaceful and secluded, yet just minutes from Clemson, Seneca, and Memorial Stadium, it’s the perfect spot for a relaxing lake stay or a game weekend getaway.

Lake Keowee Cabin: Peaceful and Bright
Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Lakefront Getaway~Dock~Fire Pit~Kayak & Games!
This 4-bedroom home is in a prime location & has EVERYTHING you need for an amazing vacation in Seneca, SC! • Screened-in Porch w/ Fireplace + Outdoor TV • Dock, Kayak & Paddles! • Fire Pit • Outdoor Patio/Dining • BBQ Grill • Board Games • Fully Stocked Kitchen • Keurig & Drip Coffee Maker • Indoor Fireplace • Family Friendly- Pack n Play & High Chair • Ample Parking • Washer & Dryer • No trailers or boats allowed to be parked on site for more than 5 hours.
Popular amenities for Seneca waterfront rentals
Waterfront apartment rentals

Lake Hartwell - Hartwell Villa 8A

3BR Ground floor condo - 2.4 Miles to Death Valley

Deane's Dock Holiday Suite, (1 bedroom)

Friendship Lake Apartment

Lakeside Oasis 2BA 1BR Near Clemson, Stocked Lake!

The Sugar Shack on Lake Keowee

Lakefront Seneca Vacation Rental w/ Shared Dock!

Gameday Getaway on Lake Hartwell - close to campus
Waterfront house rentals

Dujardins Keowee Waterfront Home

Lake Keowee Home-It's like being in a tree house.

Lakeside Retreat • Pet friendly • Fire Pit

Keowee Key Luxury Condo - Stunning Views!

Johnsons Cove - Lakefront Retreat With EV Charger

Lakefront Private Cove with Boat/Jet Ski Options

Sweet Tea Retreats

Near Clemson, Hot Tub, Game Room, Kayaks, Dock
Waterfront condo rentals

Lakeside | 3-Bedroom | 1-Mile from Clemson

Lakeside Clemson Condo | 4K TV | Xbox | Queen Beds

Tiger’s Perch- 3/3- Clemson- Mountain & lake view

Condo near Clemson University-Go Tigers!

Tall Ship 304 in Keowee Key

Lodge on Hartwell 3 BR/3Ba -1 Mile to Clemson Univ

Charming Condo Lakefront

Luxury Condo - Keowee Key
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €257 | €225 | €257 | €263 | €389 | €386 | €317 | €336 | €335 | €351 | €317 | €257 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Destinations to explore
- Nashville Vacation rentals
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Gatlinburg Vacation rentals
- Savannah Vacation rentals
- Charleston Vacation rentals
- Pigeon Forge Vacation rentals
- Hilton Head Island Vacation rentals
- North Myrtle Beach Vacation rentals
- Asheville Vacation rentals
- Louisville Vacation rentals
- Clemson University
- Table Rock State Park
- Black Rock Mountain State Park
- Devils Fork State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- DuPont State Forest
- Unicoi State Park and Lodge
- Bon Secours Wellness Arena
- Ski Sapphire Valley
- Chattooga Belle Farm
- Looking Glass Falls
- Jump Off Rock
- Fred W Symmes Chapel
- Jones Gap State Park
- Dillard House Restaurant
- Fluor Field at the West End
- Falls Park On The Reedy
- Dry Falls
- Peace Center
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site





