House vacation rentals in Upstate South Carolina

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Top-rated house rentals in Upstate South Carolina

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Top guest favorite
A serene outdoor deck features two blue adirondack chairs positioned toward a lush forest view. Hot tubs are visible on the side, framed by towering trees and a clear sky that enhances the peaceful setting.
Home in Fletcher
4.99 out of 5 average rating, 184 reviews

Atrium House - Spa Retreat

Come unwind and breathe at our couples mountain spa retreat. Atrium House has been designed to feel open to the lovely mountain surroundings yet let you relax in privacy. Our outdoor therapy hot tub, indoor/outdoor gas fireplace, and spacious two-person, walk-in shower make for a getaway so tranquil, you may never make it in to nearby Asheville! We're out in the country but just over a 15-minute drive from downtown Asheville, Biltmore, Hendersonville, Asheville Airport, and dozens of breweries.

Top guest favorite
Home in Columbus
4.97 out of 5 average rating, 240 reviews

Shipyard 2.0 | Hot Tub, Waterfall, Fire + Hammock!

BNB Breeze Presents: The Green Creek Shipyard 2.0! Experience this unique container home in the heart of the Foothills! Designed and built by 3 siblings, after much hard work and thoughtful consideration went into creating this magnificent retreat! This stunning home includes: ā˜… Hot Tub! ā˜… Beautiful Custom-Built Waterfall with a daybed. ā˜… A Wrap-around Deck ā˜… Stunning Fire Pit with Adirondack Chairs + String Lights! ā˜… Sunk-in Hammock + Swings ā˜… Webber Grill ā˜… Custom Corn Hole Boards + More!

Guest favorite
Home in Westminster
4.94 out of 5 average rating, 288 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Top guest favorite
An open-concept living area features a modern kitchen with stainless steel appliances and a spacious island, complemented by a dining table. A cozy living room is equipped with a soft sectional sofa facing a mounted television and warm electric fireplace. Natural light enhances the inviting atmosphere.
Home in Greenville
4.98 out of 5 average rating, 121 reviews

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Ā Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Top guest favorite
The front of the house is showcased with a white exterior and a welcoming porch. Two rocking chairs are positioned on the porch, surrounded by planters displaying seasonal flowers. A well-maintained pathway leads to the entrance, framed by decorative brick steps and a railing.
Home in Greenville
4.97 out of 5 average rating, 235 reviews

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Top guest favorite
Home in Greenville
4.99 out of 5 average rating, 189 reviews

Designer Modern Retreat Near Downtown Greenville

Welcome to your Greenville getaway! Minutes from downtown, GetawayGVL is a designer 1950s ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA mid-century modern oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and an updated kitchen for cooking. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

Top guest favorite
A charming cabin exterior is framed by trees, with a rustic wooden porch offering scenic views of the surrounding mountains. Warm light spills from windows, enhancing the evening ambiance. The cabin's unique architecture reflects a natural aesthetic, inviting guests to unwind in the serene environment.
Home in Lake Toxaway
4.99 out of 5 average rating, 342 reviews

Cabin I Private hiking trails | Hot Tub I Sauna

Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Top guest favorite
A spacious living area is illuminated by natural light, featuring large windows with scenic mountain views. Soft, neutral-colored seating is arranged for comfort, including a cozy sectional sofa and armchairs. Decorative curtains frame the windows, enhancing the inviting atmosphere.
Home in Saluda
4.98 out of 5 average rating, 111 reviews

Orchard Hill Vintage Cottage

Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Top guest favorite
A bright living area features a spacious couch adorned with colorful throw pillows. A light fixture overhead illuminates the space. The room includes a coffee table with a small plant and has a view of the kitchen and dining area in the background.
Home in Taylors
4.99 out of 5 average rating, 109 reviews

Chic 3/2 Near Downtown Gvl, Greer & Travelers Rest

Welcome to Taylor's Grove East, a brand-new 3-bedroom, 2-bathroom home located Taylor's, Greenville's Eastside neighborhood . Boasting a modern yet cozy design, this home combines design staples with just the right pop of color. Perfect for up to 6 guests, its strategic location is a dream for explorers. Downtown Greenville, Greer, and Traveler's Rest are all within a swift 20-minute drive. Experience the charm of the Upstate and return to unwind in style. Your relaxing gateway awaits.

Top guest favorite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 229 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Top guest favorite
The exterior of Wellspring Cottage is framed by leafy trees, showcasing a welcoming entrance with a light-colored brick facade and a modern door. Natural landscaping enhances the peaceful country setting, reflecting a serene atmosphere in the quiet neighborhood.
Home in Abbeville
4.99 out of 5 average rating, 105 reviews

Wellspring Cottage

Relax and unwind in Wellspring Cottage's beautiful country setting. The perfect getaway for a couples weekend, family vacation or relaxing girls trip. From the private backyard sitting area to the beautiful interior design, you'll breathe a little deeper in this peaceful cottage. Located in a quiet neighborhood near both Abbeville and Greenwood, you'll find delicious local dining, boutique shopping, parks and beautiful, historic homes nearby.

Top guest favorite
A covered porch features wooden ceiling beams and a fan, providing a shaded area. Two adirondack chairs are positioned beside a small table, inviting relaxation. A welcoming front door is visible, with a doormat placed in front. The surrounding grass is neatly trimmed.
Home in Iva
5 out of 5 average rating, 117 reviews

Slate Roof Cottage~Farm Animals!

Take it easy at this unique and tranquil getaway in the country. Relax on the porch swing or take a walk and say hello to our farm animals. We are in the country and are certain that you will enjoy a peaceful visit. 10 miles to Historic Abbeville 5 miles to Erskine College 18 miles - Heyward Manor wedding venue 10 minutes to Diamond Hill Mine 30 minutes to Greenwood or Anderson

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