Guesthouse vacation rentals in Upstate South Carolina

The Spring Valley Retreat

Newly renovated in 2021, very comfortable guesthouse located in a quiet neighborhood just 10 minutes from downtown Greenville. Created by highly experienced bed and breakfast owners, this space is carefully crafted to be a relaxing, restful place for travelers. Two bedrooms, a kitchen with brand-new appliances, dining area, smart TV, a desktop space, WiFi, and an outdoor porch spot to enjoy nice weather days. Note that if you search the address on Google, it will pull up photos before renovation

Super Cute Modern Guest Cottage

Charming guest house 5 min to Waynesville, and 25 min to Asheville. The guest house is furnished and decorated in a modern farmhouse style with a luxurious, peaceful feel. The bed is comfy and the claw foot tub is inviting, you're sure to feel relaxed and pampered. The deck looks out over a peaceful wooded area and is an excellent spot to enjoy your coffee in the morning. This is one of two dwellings situated on close to an acre of land. You'll enjoy privacy but owner is available if needed.

Peaceful Guesthouse on 15 Acres with Pool

Trip 101 website we are #1 Airbnb in GA with a pool! Comfortable guesthouse in the country, but within 20 minutes to in-town amenities! Just four miles from I-85. Enjoy the peace and quiet of getting away from town and into this farm-like setting of the Rundell Farm. Perfect for an overnight stop from the I 85 corridor as you are traveling through or a country getaway to a serene location! Plenty of parking for bass boats, car trailers or camper. Electric hookup available for RVs/campers.

The Travelers Loft

Light and airy contemporary guest house with upscale furnishings, nestled on 40 acres of woodland and meadows. Perfect for 2-4 guests. 2.5 miles from downtown Travelers Rest and the 'Swamp Rabbit Trail'. Great for biking or walking. 25 minutes to the city of Greenville and 45 to the mountains of Asheville, NC. Located less than 30 minutes from the Greenville Airport. This second story guest house has private parking, and a beautiful deck for grilling out or just relaxing after a busy day.

Yes please we need you! Spacious w/ amazing view!

Perfectly in tact, zero damage post-Helene and with clean well water! Accessible roads and beautifully remodeled space. This home away from home boasts stunning mountain views in a beautiful & family-friendly setting with 850SF to spread out. Relax at the fire pit patio where you can soak in the beauty of nature and local wildlife. This sparkling clean home space is just 20 mins to the Biltmore and downtown AVL and only 30 mins to AVL airport. Sleeps up to 5 (or 6 including an infant)

The Guest House By The River

Our Guest House is a quaint little place perfect for couples getaway. It is located on Chauga River, with a great swimming hole and beach. Perfect location if you are interested in River rafting (Chattooga River rafting is near by). If you enjoy hiking, fishing or just enjoying outdoors this is the place for you. Guest House is located to the right of the main house, but it is private. We would love to have you!! Close to Clemson, Cashiers, Highlands, Chattooga Belle Farms.

Downtown guest house with private hot tub & deck

Cozy guest house with private deck, hot tub, and kitchenette. This fun and stylish cottage is in the heart of downtown Watkinsville within sight of OCAF and walking distance to downtown parks, restaurants, and shopping. Only 10 minutes to downtown Athens and UGA, this convenient location is great for game days or for exploring the delightful downtown. The only thing better than the pictures is the friendly, helpful host ready to make your stay the best it can be.

Blue Ridge Parkway Treehouse

This one of a kind tree top guest house is located adjacent to the Blue Ride Parkway where you can bike or hike from the back door and into Bent Creek and Mills River. It sits above the French Broad River where you can easily access the river to paddle, SUP, or fish. Perfect for 2-3 people who love the outdoors yet want to be close to the Asheville area. This property is 10 minutes to downtown and is also pet friendly.

Modern guesthouse in downtown TR

Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!