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Pet-friendly vacation rentals in Santee

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Santee

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.94 out of 5 average rating, 191 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Top guest favorite
The cottage is surrounded by greenery, showcasing a welcoming front porch with white railings. Two planters are placed at the entrance, and a swing is visible on the side. The entrance is accessible from a paved pathway leading to the door.
Cottage in Sumter
4.97 out of 5 average rating, 504 reviews

Restful Lakeside Getaway Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax and unwind. Sit on the enclosed porch and watch the water or enjoy the front porch swing where you can listen to the birds and frogs. We are 12 min. from downtown Sumter and 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens and Poinsett State Park. It is only 2 hours to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to put your feet up and rest.

Guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.89 out of 5 average rating, 218 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top guest favorite
The exterior of a quaint cottage features white siding, green shutters, and a covered porch. An American flag is displayed, and two chairs sit on the porch. A gravel driveway leads to the home, surrounded by shade trees in a peaceful setting.
Cottage in Timmonsville
4.97 out of 5 average rating, 1,021 reviews

*Cottage Near Florence and I-95* 3 Bedrooms

Located just 5 mins from I-95 and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, pls) but are not allowed on our beds. 🧺. King bed in master, 3 TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Absolutely no smoking ON OUR PROPERTY ($200 extra fee). Come stay with us!! 😊

Top guest favorite
The exterior of the cottage showcases a striking black and red color scheme. A welcoming entrance features double French doors flanked by large windows. Two comfortable Adirondack chairs are positioned on a brick patio, surrounded by lush greenery and potted plants, inviting relaxation.
Guesthouse in Sumter
4.99 out of 5 average rating, 115 reviews

The Little Cottage, Stateburg

Take it easy at this unique and tranquil getaway. The Little Red Cottage features a small bedroom with a double size bed and a closet, a spacious living room with sofa/roku TV and computer desk, and a bathroom with shower. It is nestled on 6 serene acres, among massive windswept Live Oaks dripping with Spanish moss, Palmettos, azaleas, camellia, magnolias and creape myrtle, yet so conveniently close to Shaw Air Force base, 30 mins to Columbia and Camden, close to all Sumter's attractions.

Guest favorite
The rustic log cabin is set amidst lush greenery, featuring an inviting outdoor seating area with a stylish red umbrella. The entrance is framed by vibrant plants and a decorative barrel, offering a welcoming ambiance under the clear blue sky.
Farm stay in Gaston
4.92 out of 5 average rating, 981 reviews

Congaree Vines - Rustic Log Cabin by a Vineyard!

-Enjoy a Quiet Stay in the Country! An authentic Rustic Log Cabin on the edge of a Hobby Vineyard with Port Wine from our own vineyard! An outdoor fire pit and hammock to enjoy under the stars! -Congaree Vines also has a Barn Bungalow and Woodland Cottage. Pets welcome for fee! If service pet, bring paperwork. -We are near Congaree Natl Park (33 min), Columbia, USC, Ft. Jackson, Airport, 1-26 & Hwy 77. -15% off Guided Kayaking Congaree National Park, Carolina Outdoor Adventures.

Guest favorite
The cabin exterior is shown, featuring a wrap-around deck with sturdy railings. Large windows allow for ample natural light. The building sits on a grassy area with clear blue skies above, providing a sense of space and serenity.
Tiny home in Sumter County
4.95 out of 5 average rating, 185 reviews

The Cabin at Minehill

Our cabin is located in Stateburg, SC between Columbia and Sumter and within a 5-15 minute commute to Shaw AFB and Sumter. It is a convenient stop between I-77 and I-95 and has close proximity to Poinsett and Congaree Parks and The Palmetto Trail. It sits on top of a hill offering panoramic views, quiet, and privacy. Mine Hill sunrises and sunsets are stunning. Reserve as a stopover, a retreat from the workday, or a romantic getaway and enjoy our cabin as a home away from home.

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 162 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favorite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.94 out of 5 average rating, 145 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed but the sofa also extends into a queen-sized sleeper. Please reach out with further questions or if you would like to inquire about an extended stay.

Guest favorite
An aerial view captures a spacious home surrounded by greenery, featuring a turquoise pool in the foreground. Relaxing lounge chairs line the poolside, while colorful plants add vibrancy against the evening sky transitioning into warm hues.
Vacation home in Summerton
4.96 out of 5 average rating, 118 reviews

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

Top guest favorite
A charming poolside cottage is surrounded by lush palm trees and vibrant plants. The outdoor space features a dining set on a paved patio, providing a tranquil area for relaxation. The entrance to the cottage is easily accessible, enhancing the inviting ambiance.
Guesthouse in Florence
4.94 out of 5 average rating, 902 reviews

Cottage by the Pool: Close to Interstates

Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Guest favorite
A cozy seating area is highlighted by a brown reclining couch, featuring decorative pillows. A round mirror is mounted on the wall, and floral artwork is displayed above a spacious bed. The light-toned walls complement the subtle blue accents throughout the room.
Guest suite in Columbia
4.9 out of 5 average rating, 288 reviews

Las Flores guesthouse in North East Columbia

Private spacious suite. This private suite is great for remote work or sort vacation to Columbia SC. This place locate in North East Columbia, 7 minutes to Fort Jackson military base also great for military graduation [Amenities ] refrigerator, coffeemaker, Microwave, Smart tv, couch, dining table, and of course a king size bed The neighborhood is very clean, peaceful, quiet and safe

Popular amenities for Santee pet-friendly home rentals