Vacation rentals with lake access in Santee

Find and book unique lake access rentals on Airbnb

Quick stats about vacation rentals with lake access in Santee

Total vacation rentals
Explore 20 vacation rentals in Santee
Nightly prices starting at
Santee vacation rentals start at €87 per night before taxes and fees
Verified guest reviews
Over 60 verified reviews to help you choose
Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities
Vacation rentals with a pool
20 properties feature pools
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wi-Fi availability
20 of Santee vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals
4.8 Average rating
Santee stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated lake access rentals in Santee

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A serene view from a screened porch is shown, featuring two wooden rockers facing the tranquil lake. Green grass and trees surround a private dock visible in the distance, creating a peaceful outdoor setting.

Cottage in Manning

Archie's Lake Daze Cottage No pets

Soak up the beautiful lake views from a rocker on the porch or the 2-person hammock between the pine trees. This cozy cottage has 3 BR and 2 Baths and a stocked kitchen to make you feel right at home. Enjoy fishing from your private dock or take a spin in the paddle boat or kayaks provided. After a long day on the lake, you can enjoy a game of pool, classic arcade games, darts, or board games. WiFi is provided as well as 3 smart TVs. There is plenty of parking for your vehicles and water toys.

ViewOutdoor spacesHeating

4.96 out of 5 average rating, 141 reviews

Top guest favorite

A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.

Cabin in Vance

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

NearbyViewRiver

4.91 out of 5 average rating, 275 reviews

Top guest favorite

A relaxing private patio is furnished with two chairs and a small table, offering views of Lake Marion. The serene surroundings include lush trees and a clear water edge. A rug adds a cozy touch, while a pet is seen lounging nearby, enhancing the inviting atmosphere.

Condo in Santee

Lake Life Living-W/Boat waterfront condo

Nestled in a cozy cove along the shores of Lake Marion, this pet friendly retreat offers an escape for anglers, boaters, and golfers seeking both tranquility and convenience. This 2-bed, 2-bath condo is conveniently located off I95, making it an excellent base for exploring nearby areas. Lake Marion ranks among the largest lakes in the US offering world-class fishing. Santee also provides an exceptional golfing challenge making this a premier vacation destination for the golf enthusiasts.

ViewNearbyQuiet

4.91 out of 5 average rating, 45 reviews

Superhost

A spacious bedroom features a large bed dressed in white linens, complemented by decorative pillows. Nightstands with soft lamps are placed on either side. Wooden walls provide a rustic backdrop, with two windows adorned by patterned curtains allowing gentle light to filter in.

Bungalow in Summerton

The Turtle's Nest

Locally known as the "Turtle's Nest", you will be close to all the action. Located on Goat Island, 2nd row back, right off the big water. Boat ramp, boatslip, and restaurant only .3 miles away. Ramp and beach picnic area included. Remodled to a farmhouse feel, this 3 bedroom, 1 bath has 2 king beds & two singles. Two single beds share the same space as living room. Great retreat after a long day of fishing, or hanging out with family and friends. Be back fast to unwind by the firepit.

ViewOutdoor spacesFamily

4.79 out of 5 average rating, 138 reviews

Top guest favorite

Home in Manning

Lakefront Retreat | Dock, Firepit & Dog Friendly

Wake up to panoramic Lake Marion views, fish from your private dock, relax around the waterfront firepit, and enjoy a peaceful lakefront getaway just steps from the water. Enjoy peaceful mornings, sunset evenings, and easy access to fishing, boating, swimming, and lake life. Dog Friendly: Well-behaved pets are welcome! Please keep pets off furniture and clean up after them inside and outside the property. Multiple dogs may be considered case-by-case—please message us before booking.

NearbyOutdoor spacesLong stay

4.97 out of 5 average rating, 32 reviews

Guest favorite

A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.

Guest suite in Eutawville

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

NearbyViewCondition

4.81 out of 5 average rating, 107 reviews

Superhost

Aerial view of a lakefront property shows a private dock extending into calm waters, surrounded by lush greenery. The house, nestled among trees, features a spacious yard with a fenced area and a screened porch visible. The tranquil setting emphasizes the natural beauty of the location.

Cottage in Manning

A Great Lake house. Near Manning, SC and I-95.

Secluded and serene, our private lakefront property in South Carolina's Lake Marion region offers a community feel with minimal traffic and noise. The fenced-in property has 2 cozy bedrooms, a large open floor plan, and a screen porch with a beautiful lake view. Enjoy the private dock, kayaks, and floats, and relax with a bonfire and grill. Conveniently located just 20 minutes from Manning and I-95, our retreat is perfect for travelers looking to unwind and recharge.

Outdoor spacesNearbyGrill

4.75 out of 5 average rating, 174 reviews

Top guest favorite

A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.

Home in Summerton

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

NearbyViewLaundry

4.99 out of 5 average rating, 134 reviews

Guest favorite

Vacation home in Summerton

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

NearbyOutdoor spacesLayout

4.95 out of 5 average rating, 139 reviews

Guest favorite

Home in Summerton

Lake Marion | Chill, Cruise, or Cast a Line for 8!

Wake up to quiet mornings, sip coffee by the water, cast a line, and let the day slow down. This Lake Marion home is all about relaxing, fishing, and unplugging with your favorite people. This is the perfect place to reset, recharge, and enjoy the simple things. No rush. No noise. Just lake life, done right. PS: this IS a fresh water lake in SC with a lot of wildlife, including alligators...swim, fish, and play at your own risk.

ViewOutdoor spacesIndoor spaces

4.81 out of 5 average rating, 31 reviews

Guest favorite

Cabin in Eutawville

Reelaxation-At Lake Marion

Unplug and enjoy the laid back charm of this cozy 2BR cabin near Lake Marion. Located in a gated community, it features a private boat ramp, boat parking, and plenty of space to relax and grill after a day of fishing on the lake or golfing at one of local golf courses. Enjoy peaceful mornings, family and friend time, and quiet evenings on the porch. Perfect for anglers, golfers, and family getaways.

NearbyCleanlinessHospitality

4.88 out of 5 average rating, 8 reviews

Top guest favorite

Home in Eutawville

Boogs Cabin at Lake Marion

Boogs Cabin at the Lake is your cozy, laid back getaway on the big water of Lake Marion. With three comfortable bedrooms (1 King 2 Queen), bonus game room that also has a pull-out full bed and two sleeping cots, large sliding glass doors in the living room that invite natural light in and offer views of the great outdoors it's the perfect place to play, recharge and reconnect.

ViewOutdoor spacesParking

5.0 out of 5 average rating, 16 reviews