Seneca vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in Seneca
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca vacation rentals
Other great vacation rentals in Seneca
Guesthouse in Townville
4.88 out of 5 average rating, 230 reviewsLisa’s Lodge
Jun 19 – 26
Home in Pendleton
4.89 out of 5 average rating, 129 reviewsComfort & Convenience Close to Campus
Jun 29 – Jul 6
Guesthouse in Toccoa
4.99 out of 5 average rating, 108 reviewsCozy Rustic Lakefront Cabin
Jul 16 – 23
Cottage in Central
5.0 out of 5 average rating, 160 reviewsCozy Cottage on Oak Grove
Jun 28 – Jul 5
Guest suite in Hartwell
4.97 out of 5 average rating, 209 reviewsRelaxing retreat on Lake Hartwell.
Dec 8 – 15
Home in Anderson
4.99 out of 5 average rating, 178 reviewsLake Escape
Feb 23 – Mar 2
Guest suite in Central
4.97 out of 5 average rating, 144 reviewsElfwing Carriage House
Oct 12 – 17
Cabin in Seneca
4.81 out of 5 average rating, 83 reviewsGetaway Lake Hartwell - Greenville
Jul 24 – 31
Other great vacation rentals in Seneca
Home in Seneca
5.0 out of 5 average rating, 47 reviewsModern & Cozy Cottage-12 min. from Clemson Uni.
Aug 2 – 9
Home in Westminster
4.94 out of 5 average rating, 16 reviewsMountain Road Cottage
Nov 9 – 16
Cottage in Seneca
5.0 out of 5 average rating, 32 reviewsThe Cottage
Jul 15 – 22
Cabin in Townville
5.0 out of 5 average rating, 23 reviewsThe Frog Hollow
Feb 17 – 24
Cottage in Central
5.0 out of 5 average rating, 30 reviewsThe Wildflower
Jan 30 – Feb 6
Cottage in Seneca
5.0 out of 5 average rating, 50 reviewsKeowee Waterfront Lakeside Retreat -Keowee Cottage
Dec 17 – 24
Cottage in Seneca
4.99 out of 5 average rating, 81 reviewsClemson/Lake Hartwell cottage
Jun 5 – 12
Cottage in Seneca
4.98 out of 5 average rating, 52 reviewsBountyland Cottage ~ Lake Keowee & Clemson
Jan 31 – Feb 7
Quick stats about vacation rentals in Seneca
Total rentals
50 properties
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
1.7K reviews
Nightly prices starting at
€ 37 before taxes and fees
Frequently Asked Questions
Are there vacation rentals with a dedicated workspace in Seneca?
Yes! Work meets play with ease at over 20 vacation rentals in Seneca featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Seneca?
Four-legged friends are welcome in Seneca. Choose from more than 10 vacation rentals for guests traveling with pets.
How much does it cost to stay in house rentals in Seneca?
Experience the best of Seneca with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Seneca have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Seneca. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly house rentals in Seneca?
Seneca has more than 30 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Seneca have wireless internet?
Absolutely! We offer over 30 house rentals with wireless internet in Seneca. Enjoy a tailored experience with all the comforts you desire.
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