
Guesthouse vacation rentals in La Mesa
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Top-rated guesthouse rentals in La Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private 1 BR Paradise retreat
Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

Da Hui Hut - La Mesaās best view and spa
Da Hui Hut is a very private oasis uniquely situated at the top of San Diego county's magnificent Mt. Helix. At roughly 1,300 feet above sea level, Mt. Helix is the crown jewel of natural landmarks in the area. The landscape provides bountiful views, and the large deck is positioned perfectly to see it all. It feels like you're on top of the city! Inside, guests will encounter Californian and Hawaiian inspired decor as they collide with wooden walls to compose a symphony of color and good vibes.

NEW construction - Studio near the Village
New studio - Attached Dwelling Unit (ADU) with a private entrance. Walking distance to the Village of La Mesa which has several restaurants, shops and a Vons. Very close to SDSU and quick access to multiple freeways that take you to beaches, mountains, SD Zoo, the nightlife in downtown SD (8, 94, 125). Access to shared laundry room, 2 parking spaces and its own outdoor area. AC & heat. WiFi. Netflix, Hulu with live TV, Apple TV, Disney +, Prime Video and HBO Max. Crib and high chair upon request

Stunning Guest House 15 min. from Zoo, Downtown
Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental!Ā Ā Our casita is newly remodeled with luxury ammenities.Ā We proudly cater to the cannabis community and non-users alike.Ā Ā Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest.Ā This ensures that every guest checks into a clean, fresh-smelling place that feels like home.Ā Ā Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
This is the perfect Guest House with a salted & heated pool & hot tub. We are located in a super quiet & very safe neighborhood in beautiful San Diego, 15 minutes drive to Downtown, La Jolla, Beaches, Zoo, Sea World & Convention Center. Hike next door at Mission Trails & Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo and top quality finishes await you inside. Everything you need for memorable vacation! No smoking or vaping on the property.

Private Studio with a Panoramic View
Escape to Your Hilltop Retreat! Relax in secluded studio. Sip wine by the cozy fire pit or unwind on the patio with a birdās-eye view. Conveniently located just 15-20 minutes from the beach and downtown, youāre never far from the action. Plus, well-behaved pets are always welcome. Bringing more friends or family along with you? We also have another listing, The Eagles Nest at the same property.

Mountain View Retreat in Gated Estate (Hot Tub)
Perched above a canyon with spectacular panoramic mountain views, this private guest house is a secluded retreat in one of San Diegoās most eclectic and desirable neighborhoods less than 6 miles from the Downtown San Diego airport. Enjoy a fully equipped kitchen, luxe king size bed and dual sliding glass doors that open to an expansive deck with patio seating, private hot tub and BBQ area.

Spacious, private Mt. Helix country style studio
Located in a quiet and lush neighborhood, in hills of La Mesa. This private studio has everything you need to relax and experience the California life: comfy queen size bed, full kitchen, patio, bbq, and fire pit. Within walking distance to Mt. Helix Historic Park for a spectacular 365-degree view of San Diego. You are 20 minutes from the beach, airport, and mountains.

La Mesa Suite
Mi mesa es su mesa, a beautiful newly built home in sunny La Mesa. Easy access to centrally located shopping center, SDSU and up and coming downtown La Mesa. Short drive down the 8 freeway to the mission beach and downtown SD. Includes everything you need in your home away from home while also providing comfort, security and privacy.

Casa Sierra on Mount Helix
Enjoy a newly remodeled bedroom and bathroom with a private entrance. The space is completely separate from the rest of our home, offering peace, quiet, and total privacy. Inside, youāll find a brand-new, comfortable bed, plus modern conveniences including a Smart TV, WiFi, mini fridge, microwave, and Keurig.

Private Poolside Cabana
Poolside cabana with incredible mountain view in the Mt. Helix area. Located 20 mins - Downtown and beaches. 10 mins - SDSU and trolley. Bottle of wine waiting with comfortable King sized bed and luxury bathroom. Small kitchen area includes Keurig, microwave, blender, toaster and small fridge.
Popular amenities for La Mesa guesthouse rentals
Family-friendly guest house rentals

"Glam Farmhouse dream cottage"š š

Private Modern Studio with Ocean View

Cosy quiet Guesthouse near SDSU

Granny Flat with Bedroom/Bathroom/Kitchen

Cozy Casita

Mid Century Studio Bungalow Near SDSU

Mt Helix Studio Loft with Mountain Views

Brand New Modern North Park View Apartment
Guest house rentals with a patio

Santorini-Inspired Cottage w/ Hot Tub + Views

Adorable cottage in Talmadge

Amazing Views! Private Hilltop Home with Balcony~

La Jolla Oasis: Ocean, City and Fire Works Views

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

*KING BED* Colorful Guesthouse by Downtown

Heart of SD | Zoo Nearby | Private Patio | Central

Loft Cabin ā¢SoakTubā¢Cinemaā¢View +Zoo pkg add-on
Guest house rentals with a washer and dryer

Lovely Guesthouse in garden setting

Charming Guest House in Poway - Kid friendly

BEAUTIFUL Private Studio

Modern mountain guest house. Incredible views

New Guest House - North Park

Clean Cozy Private Guesthouse | Central San Diego

Point Loma Private Apartment

PRIVATE VISTA SUITE/ CENTRAL SAN DIEGO 1BED/1BATH
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ā¬Ā 106 | ā¬Ā 107 | ā¬Ā 105 | ā¬Ā 101 | ā¬Ā 112 | ā¬Ā 117 | ā¬Ā 123 | ā¬Ā 109 | ā¬Ā 101 | ā¬Ā 105 | ā¬Ā 106 | ā¬Ā 102 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about guesthouse rentals in La Mesa

Total vacation rentals
Explore 90 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at ā¬Ā 43 per night before taxes and fees

Verified guest reviews
Over 6,100 verified reviews to help you choose

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
90 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guestsāaveraging 4.9 out of 5!
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