
Villa vacation rentals in La Mesa
Find and book unique villas on Airbnb
Quick stats about villa rentals in La Mesa

Total vacation rentals
Explore 10 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at €51 per night before taxes and fees

Verified guest reviews
Over 540 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.7 Average rating
La Mesa stays receive an average rating of 4.7 out of 5 from guests
Top-rated villa rentals in La Mesa
Guests agree: these villas are highly rated for location, cleanliness, and more.

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.
Enjoy a stylish experience at this centrally-located place. Great place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. 5 min from trails and Cowles Mountain. 15 min to Sea World, Animal Park, beaches, parks, downtown, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more! 2 min to a kid playground. Nice Villa in a really nice and Quiet Neighborhood, but will also accommodate your best party!

The Kensington Canyon Estate
Beautifully restored Kensington retreat blending historic charm with modern luxury. Approaching its 100th anniversary, this home has undergone a complete $250,000 renovation, offering the comforts of brand-new construction while preserving its timeless character. Located on quiet Hart Drive in one of San Diego’s most beloved historic neighborhoods, guests can enjoy tree-lined streets and walkable cafés, restaurants, and shops—just minutes from beaches, Balboa Park, downtown, and top attractions.

Resort Villa w/ Waterslide, Pool, Spa, Pickleball!
Escape to your own private San Diego resort, where every day feels like vacation. Whether you're racing down the waterslide, relaxing in the spa, playing pickleball, grilling by the pool, or gathering with family in the game room, there's something for everyone to enjoy. Tucked away in a peaceful hillside setting just minutes from San Diego's top attractions, this spacious five-bedroom retreat offers the perfect balance of resort-style amenities, comfort, and privacy for an unforgettable stay.

@Fantastic villa, giant pool, guest house, golf !
This unique fantastic villa with a separate pool house sitting on 1 acre with a spacious living space with large windows. Main house has 4 bedrooms with 2 baths, and a guest house has 1 bedroom with 1 bath. +8 car parking, nice privacy and a fantastic view! Brand new giant size SALT pool with huge size jacuzzi, pool toys, golf zone, a huge grass event field, game field, pool table, foosball, ping pong, Nitendo,2 fire pits and more! Truly one-of-a-kind property don’t miss out! ToT:COSD-00749

Hidden Villa with Beautiful Furnished Garden Patio
Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome. 2 gig internet w/high speed router

Private oasis
Enjoy this gorgeous farmhouse style two story home with 2 master suites and your own private getaway oasis with amazing views from every window, no neighbors around, pool, spa, a large brand new kitchen with a huge entertainment island and pretty much everything you need for your next getaway. Despite being super secluded, it’s located a block away from a taco shop, 2 blocks from 7 Eleven, 3 minutes drive from main shopping areas with grocery stores, and restaurants as well as the 94 and 8

Historic Villa, Blocks from the Beach, Ocean Views
Built in 1923, this beach town retreat has tons of old world charm with all the modern amenities. Only 6 blocks to the beach, you couldn't ask for a better location. Dog Beach, Sunset Cliffs and some of the best bars, restaurants and vintage shops in all of San Diego are just outside your doorstep. ☞ 3 Bedrooms ☞ Private Hot Tub ☞ Private Swimming Pool ☞ Outdoor Dining ☞ Ocean Views (perfect for sunset cocktails) ☞ Outdoor Grill ☞ Bikes to enjoy the neighborhood ☞ Chef's Kitchen

Luxury Dream Home Stunning 360 Views of SD
┏━━━━✦❘༻ WELCOME HOME ༺❘✦━━━━┓ ✦ Arguably the most stunning views in San Diego ✦ This Villa with a private Guesthouse captures all of San Diego including the Beaches, Coronado & Downtown ✦ Lounge in the numerous outdoor areas ✦ Walk the expansive wrap-around deck and choose where you'd like to see the sunsets and sunrises ✦ One of the few properties where you can see both! Climb the historic rock and be at the top of San Diego ✦ Famous Landmark - A piece of San Diego History

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀
Brand New Property! Massive garden of Eden style resort home with sprawling outdoor entertainment area and spacious open concept inside, perfect for large families with kids and responsible adults. Updated top to bottom with all new outdoor and indoor furniture, modern upgrades in all bedrooms and common areas. Centrally located and 20 minutes from the beach and all of SD's top attractions! 8 person hot tub, sparkling saltwater pool and new outdoor kitchen. Don't miss out!

Gorgeous Beach Villa | Ocean Views + Sleeps 12!
Experience the ultimate family retreat in our spacious 6-bedroom, 4-bath home with breathtaking views of Mission Bay and the Pacific Ocean. Perfect for groups, it features two kitchens, multiple balconies, and a large backyard with a fire pit and grill. Walk to Ocean Beach and Sunset Cliffs or explore nearby attractions like SeaWorld and Balboa Park. Unwind with sea breezes, sunsets, and the sparkle of SeaWorld fireworks. Your unforgettable San Diego getaway starts here!

Breathtaking Hillside Estate w/ Luxury Amenities
Welcome to your private hillside villa near San Diego, designed for families and respectful groups who want space, comfort, views, and resort-style amenities. Enjoy peaceful indoor-outdoor living with a private pool, spa, sauna, gym, game room, BBQ, and multiple lounge areas overlooking the hills. The home is located in El Cajon, about 30 minutes from Downtown San Diego, Gaslamp, Little Italy, and the airport, and about 35 minutes from the beach.

1stResorts.com WATER VIEW FAMILY VILLA A w/ HOTTUB
Brand New FAMILY Villa with Water Views from the kitchen / living area! Special reduction for week long stay!! Two level Villa. Large deck attached. Hot Tub, Barbecue Grill, Fire pit! Beautiful sunsets!! Come stay with us and enjoy all of San Diego's finest. We are located close to Balboa Park, Coronado and so many great venues and experiences or just stay on site and enjoy your very own Oasis!
Popular amenities for La Mesa villa rentals
Private villa rentals

Amazing WaterView Penthouse w/AC

The Bonita Bungalow

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.

Hidden Villa with Beautiful Furnished Garden Patio

@ Paradise villa, Top view, 4600sqrt on 10 acres

Resort Villa w/ Waterslide, Pool, Spa, Pickleball!

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀

@Fantastic villa, giant pool, guest house, golf !
Luxury villa rentals

Amazing WaterView Penthouse w/AC

1stResorts.com AMAZING WATER VIEW PENTHOUSE HOTTUB

3680 Bayside Walk, A Bayside Marina

Cheerful 4-bedroom villa with free parking.

*Huge HelixCastle-PanoramicView/20+guests welcome
Villa rentals with a pool

1 PRIVATE OCEAN VIEW ROOM IN LUXURY COASTAL HOUSE

LUX Sunset I Solar-Heated Pool • Games • FirePit

San Diego 4BR family home| Pool| Deck| RV Parking|

2 Private Ocean View Suites-in Shared LuxuryVilla

@ Paradise villa, Top view, 4600sqrt on 10 acres
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