
House vacation rentals in Simpsonville
Find and book unique houses on Airbnb
Top-rated house rentals in Simpsonville
Guests agree: these houses are highly rated for location, cleanliness, and more.

Fenced in Yard, 2 Queen Beds, Downtown!
Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Private Guest Suite in Convenient and Quiet Area
A dedicated walkway with motion activated light leads up to your private entrance in a nice, quiet neighborhood located near the I85-385 intersection. This isn't a shared or basement unit, it's a first floor unit w/ private entrance for convenient check-in. There's no shared space/kitchen included, this is a separate rental space within my home. This suite is available for mature guests (min 25) who respect quiet, it's close to restaurants, shopping, GE Vernova, Fluor, Michelin, GSP, etc.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Designer Modern Retreat Near Downtown Greenville
Welcome to your Greenville getaway! Minutes to downtown, GetawayGVL is a designer 1950s ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA mid-century modern oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and an updated kitchen for cooking. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

Modern Farmhouse in Downtown Simpsonville, SC
Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Simpsonville Southern Comfort
Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Claire's tearoom / artist suite
One bedroom suite, under the sun-room with 4 windows overlooking the private garden; private entrance and completely separate from the main house; Individual mini split A/C unit in suite for your ultimate comfort; Huge working desk with plenty natural lights. Enjoy your morning tea or coffee in the garden; Relaxing and reading on the custom build banquette; super comfy Queen Size bed (Brand new mattress as of March 2024); separate area of bathroom, shower, sink and KITCHENETTE.

Greenville Modern Retreat - 8 minutes to Downtown
Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Updated 4 BR Family Friendly Escape w/ Swingset
>>Experienced SuperHosts!<< This stylishly updated home is conveniently located just 3 minutes from the shopping & dining in Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house is perfect for families, groups of friends, and workers on assignment in the area! Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs.

Family & Pet Friendly Home - Sleeps 8
Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Water Oak Retreat / Comfy king bed, big back yard!
-Private deck with grill and eating area - Fully stocked kitchen with tea, coffee and snacks -Safe and quiet neighborhood -1 mile from all of downtown Simpsonville's shops and restaurants -1 mile to huge park with playground, tennis, basketball, and farmers market -Short 20 minute drive to downtown Greenville -Perfect for families and those traveling for work
Popular amenities for Simpsonville house rentals
House rentals with a pool

Pet-Friendly 4BR: Pool, Screen Porch, Fenced Yard

Upstate Getaway at the Relaxing Ranch

The Wright Place! 25/min DT G-Ville. Pool/Hottub.

Shalom House with Pool near DT Greer SC

Pickleball, Ping-Pong, King beds, BonFire Nights!

Greenville Bungalow w/ Stock Tank Pool + Fire pit

Spacious 3 BR house with private backyard oasis.

Brand New Charming home in heart of Moore
Weekly house rentals

Fully Furnished Cozy Cottage

Carolina's Olde Mill, family friendly

18 Hidden Gem - Private Home - 3 BDRM In 5 Forks

Modern Cottage in the Woods w/ Hot Tub & Firepit

Cute cozy house in a quiet secluded area.

Mountain Villa 15min from Downtown Greenville

Spacious 3BR W Loft In cul-desac

Spacious Retreat w/ Game Room & Outdoor Oasis
Private house rentals

Mauldin 3bdroom-Maverick Ranch STR23-000002

Pond View (8 Min to GSP)

Bohemian Bungalow

Luxury spacious 4 bedroom home

Southern Luxury Retreat in Greer

Whimsical 4 bedroom house with a cozy backyard

House Frieda

Heart of Fountain Inn: 2BR Gem
When is the best time to visit Simpsonville?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | € 111 | € 108 | € 105 | € 104 | € 109 | € 109 | € 103 | € 110 | € 107 | € 109 | € 104 | € 115 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 20°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Quick stats about house rentals in Simpsonville

Total vacation rentals
Explore 70 vacation rentals in Simpsonville

Nightly prices starting at
Simpsonville vacation rentals start at € 26 per night before taxes and fees

Verified guest reviews
Over 2,180 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
70 of Simpsonville vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

4.8 Average rating
Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!
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- Rentals with a fire pit Simpsonville
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- Pet-friendly rentals Simpsonville
- Rentals with a fireplace Simpsonville
- Rentals with outdoor seating Simpsonville
- Rentals with a patio Simpsonville
- Family-friendly rentals Simpsonville
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- Gorges State Park
- Tugaloo State Park
- Table Rock State Park
- Chimney Rock State Park
- Lake Lure Beach and Water Park
- Jump Off Rock
- Tryon International Equestrian Center
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Burntshirt Vineyards
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- City Scape Winery
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