House vacation rentals in Pickens County

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Top-rated house rentals in Pickens County

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Top guest favorite

A charming cottage is nestled among tall trees, featuring a bright white exterior with dark brown accents. The front porch is accessed via a wood bridge, inviting guests to enjoy the natural surroundings. A small garden area is visible in front of the entrance.

Home in Greenville

4.89 out of 5 average rating, 140 reviews

Oakwood Cottage at Saluda River Farms

This cozy 400sqft space is the middle cottage of the 'Art' Studio. It has everything you need to enjoy a weekend get away. Saluda River Farms is an 8 acre farm on the Saluda River. Bring your Kayaks to enjoy a relaxing trip up the river or ride your bike on the beautiful back country roads. We are located 7 miles from DT Greenville and only 20 minutes from nature hikes and quaint little country towns. You can also relax on the farm - we have 3 goats and 8 chickens. Pets are always welcome.

Top guest favorite

The exterior of a charming brick house is framed by lush greenery. A stone pathway leads to the entrance, flanked by well-maintained shrubs and trees. Large windows allow natural light to fill the living spaces inside, providing a welcoming exterior view.

Home in Pickens

4.96 out of 5 average rating, 107 reviews

Welcome to Downtown Pickens

This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Top guest favorite

A modern one-story ranch house is depicted in a tranquil setting, featuring a spacious driveway and manicured landscaping. Natural light illuminates the exterior, enhanced by a welcoming entryway with decorative planters and a covered porch, surrounded by lush greenery and large trees.

Home in Travelers Rest

5 out of 5 average rating, 132 reviews

Modern Wooded Retreat

Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Top guest favorite

The living area features a plush reclining couch positioned toward the kitchen. Industrial-style light fixtures hang from the ceiling's exposed beams, illuminating the open layout. A modern kitchen with stainless steel appliances and a large island is visible in the background, complemented by natural light from outdoor views.

Home in Central

4.97 out of 5 average rating, 156 reviews

Clemson Carriage House | Private Guest House

In July of 2018, new construction began on the Clemson Carriage House and it was completed in January of 2019. This private, stand alone house sleeps 5 and there is another new listing called the Clemson Studio Retreat which is a 4 person adult studio if you have friends that want privacy and a separate kitchen and laundry. The house looks out on the woods as the pictures indicate and is a great alternative to hotels. There is more privacy and less price ! Parking available for RVs and boats.

Top guest favorite

A serene bedroom features a four-poster bed draped with soft textiles, complemented by cozy fur accent pieces. Warm lighting creates a relaxing ambiance, while decorative wall frames and patterned rugs enhance the inviting atmosphere. Multiple windows allow natural light to filter in.

Home in Easley

4.99 out of 5 average rating, 104 reviews

Comfy, cozy duplex apt in old home downtown Easley

Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

Guest favorite

A lush green lawn extends across the image, framed by trees and a backdrop of rolling hills. A bright blue sky dotted with fluffy white clouds adds to the serene atmosphere. The spacious landscape offers a tranquil view of the surrounding nature.

Home in Liberty

4.93 out of 5 average rating, 115 reviews

3 Bed Home Overlooking Fishing Pond on 10 Acres

This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Guest favorite

A newly constructed duplex is depicted, featuring a light grey exterior with black shutters. The entrance is framed by two elegant chairs on the porch. A spacious driveway leads to a well-maintained area, surrounded by neat landscaping and a clear blue sky.

Home in Pickens

4.96 out of 5 average rating, 139 reviews

Cottage in Pickens

Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

Guest favorite

An aerial view showcases a serene landscape featuring a four-acre pond surrounded by lush greenery and autumn foliage. A winding driveway leads to a guest house nestled within the wooded area. Rolling hills provide a backdrop, enhancing the natural beauty of the property.

Home in Pickens

4.96 out of 5 average rating, 157 reviews

Our Slice of Heaven w/Views of Table Rock-Pickens

Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

Top guest favorite

The living room features two dark gray sofas arranged around a round coffee table, which holds a decorative bowl. A colorful area rug adds warmth to the hardwood floor. Soft lighting is provided by two lamps beside the sofas, and a large mirror hangs on the wall.

Home in Easley

4.96 out of 5 average rating, 372 reviews

Pet-Friendly Country Home | Clemson & Greenville

Stay at a Top 1% Airbnb Home in the scenic Blue Ridge foothills! This 3BR retreat sleeps 8, is pet-friendly with a fenced yard, and perfectly located near Clemson, Greenville, & Easley. Relax in comfort with plush beds, Smart TVs, and family-friendly extras. We provide coffee, snacks, linens, 1 towel\washcloth for each guest, soaps, and detergents so you can settle in instantly. Your perfect getaway starts here!

Top guest favorite

A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.

Home in Seneca

4.96 out of 5 average rating, 112 reviews

Cozy 3 Br Family Home • 5 min to Clemson Campus

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Guest favorite

A living area is presented with a brown leather sofa and a white coffee table atop a textured rug. Light is provided by a ceiling fan and window, accompanied by framed artwork on the walls. A wall-mounted television is visible opposite the seating arrangement.

Home in Easley

4.89 out of 5 average rating, 164 reviews

Livin' Easley-walk to downtown-close to everything

Welcome to Livin' Easley! Your family will be close to everything when you stay at this newly renovated bungalow style house. Downtown Easley shops, restaurants, bars and The Silos are within walking distance, and Greenville and Clemson are just a short drive away. If you'd rather stay in, enjoy everything the house has to offer including bumper pool, a card table, board games, horseshoe pits, and Netflix.

Top guest favorite

The exterior of a spacious single-story home features a red metal roof and light-colored siding. A welcoming blue front door is positioned under a small porch, surrounded by green shrubs. A gravel driveway leads up to the house, framed by trees and a clear blue sky.

Home in Central

4.98 out of 5 average rating, 113 reviews

The House on Oak Grove

Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.