
House vacation rentals in Pickens County
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Top-rated house rentals in Pickens County
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Vacation rentals for every style
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Popular amenities for Pickens County house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

Clemson football 15 minutes away. 2 night minimum.

Lake Keowee Home near Clemson, boating, and hiking

Historic Pendleton SC

Golf view, lake access, 3 pools!

* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*

Cottage close to Clemson
Weekly house rentals

Lake Keowee Beach Club Cabin

Greenville's Lazy Lodge

Cozy Foothills Retreat

Spacious Lakefront *Gem* Pet & Family Friendly

Rare 1930’s Riverfront Cottage

Mountain Retreat | 7 Acres | Arcades | Hot Tub

Frankie’s Place

Cozy Brick House
Private house rentals

Singing Pines Cottage

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Cozy 2BR Cottage | Close to Clemson & GVL

Lakefront luxury home w/panoramic view & Boat Slip

The Llama Retreat Beautiful, Cozy Bungalow!

Whispering Meadow Cottage

Discounted Clemson home games!

Convenient to Clemson/Greenville/Anderson
Destinations to explore
- Rentals with a fireplace Pickens County
- Rentals with a fire pit Pickens County
- Rentals with a kayak Pickens County
- Apartment rentals Pickens County
- Pet-friendly rentals Pickens County
- Guesthouse rentals Pickens County
- Rentals with outdoor seating Pickens County
- Family-friendly rentals Pickens County
- Waterfront rentals Pickens County
- Fitness-friendly rentals Pickens County
- Rentals with a washer and dryer Pickens County
- Condo rentals Pickens County
- Private suite rentals Pickens County
- Rentals with pools Pickens County
- Rentals with a patio Pickens County
- RV rentals Pickens County
- Cabin rentals Pickens County
- Rentals with lake access Pickens County
- Rentals with breakfast Pickens County
- Rentals with a hot tub Pickens County
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Table Rock State Park
- The North Carolina Arboretum
- Tallulah Gorge State Park
- Chimney Rock State Park
- Tugaloo State Park
- Mountaintop Golf & Lake Club
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Maggie Valley Club
- Jump Off Rock
- Biltmore Forest County Club
- French Broad River Park
- Vineyards for Biltmore Winery
- Victoria Valley Vineyards
- Woolworth Walk
- Old Edwards Club
- Discovery Island
- Thomas Wolfe Memorial