
Pet-friendly vacation rentals in Pickens County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Pickens County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Welcome to Downtown Pickens
This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.
4.96 out of 5 average rating, 133 reviews
Private Waterfall Apt | No Shared Spaces | pets+
Our charming apartment is nestled in the woods with a prime view of your own private 15 ft waterfall in the backyard. Enjoy peace & tranquility while reading a book on the hammock or warm up by the chiminea while watching the fireflies scatter about the woods. The creek is approximately 3 ft deep at the bottom of the waterfall. The property is surrounded by State Forest. If the apartment gets rented, the rest of the house is blocked from being rented. You will not be sharing ANY space.
4.98 out of 5 average rating, 409 reviews
Modern Wooded Retreat
Come relax with the whole family in a place you'll never want to leave! Just 5 min. to downtown TR, and less than 20 min to downtown Greenville! Watch movies under the stars, roast marshmallows by the firepit, play cornhole and giant sized yard games in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. We'd love to host you, while you explore everything Greenville and Travelers Rest have to offer.
5.0 out of 5 average rating, 184 reviews
Creekside Cabin where you can truly relax.
Quiet creek-side cabin on 2 1/2 acres where the Eastatoee creek will provide you with the best night's sleep. The spectacular Twin Falls is a short walk from the cottage. Enjoy trout fishing, cycling, floating, or cooking out on our rock BBQ grill. If you're a sports fan of Clemson Tigers or Furman Paladins, it’s only 45 minutes away. Travel to Picturesque Cashiers or Highlands, known for their boutiques. Are internet is fast fiber optic for those who want to get away but still keep in touch.
4.95 out of 5 average rating, 108 reviews
Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"
4.96 out of 5 average rating, 165 reviews
Alinea Farm
Alinea Farm is a working family farm. We are a 10-acre homestead full of farm animals and gardens. The airbnb is newly remodeled and situated above our detached garage. While our family home is not far, we have created a private space and are very mindful to provide quiet, peace, and privacy for our guests. We are hosts at heart and are here to accommodate whatever you need from your stay, whether to be left in peace to a lively tour around the farm. We hope you will find rest here.
4.98 out of 5 average rating, 283 reviews
Comfy, cozy duplex apt in old home downtown Easley
Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode
4.99 out of 5 average rating, 146 reviews
3 Bed Home Overlooking Fishing Pond on 10 Acres
This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too
4.93 out of 5 average rating, 161 reviews
Peace-In-The-Forest Retreat
PEACE-IN-THE-FOREST RETREAT offers a reprieve by providing privacy & quiet in a beautiful, custom-built cabin, on 100 forested acres w/ miles of hiking trails. REGARDING COVID-19, we provide a healthy place to be, breathe & move & WE ARE GOING THE EXTRA MILE to ensure that all touchable surfaces in our cabin are sanitized. We are 20-40 minutes from 6 SC State Parks+Dupont Forest, State Heritage Preserves; Lakes Keowee, Jocassee & Hartwell; Foothills trail &more!
4.95 out of 5 average rating, 186 reviews
Hobbit Hideaway- Do Something Different!
Trek back from Mordor and retire to a full kitchen, AC/heat, queen bed, pullout couch w/ new memory foam pad, washer/dryer, shower and more. Enjoy the patio where you can be the lord of the fire ring, grill PO-TAY-TOES, enjoy the swing, hammock, horseshoes, axe throwing, games and more. Located 12 min from beautiful Traveler’s Rest, where you can run/bike your little hobbit heart out on the 22-mile Swamp Rabbit trail. Also 30 min from downtown Greenville.
4.98 out of 5 average rating, 392 reviews
Pet-Friendly Cabin in Marietta w/ Porch Swings
Welcome to Copper Valley Retreat, a peaceful cabin getaway nestled in a quaint valley in Cleveland, SC. We are located: 10 min to Table Rock State Park 30 min to Jones Gap State Park 30 min to Pretty Place Chapel + Caesar's Head 40 min to DT Greenville Enjoy hiking, swimming, fishing, cycling and more at your new favorite cabin retreat. Our front porch rocking swings are the perfect place to relax. We can't wait to welcome you to our peaceful oasis.
4.85 out of 5 average rating, 106 reviews
5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.
4.96 out of 5 average rating, 150 reviewsPopular amenities for Pickens County pet-friendly home rentals
Pet-friendly house rentals

Clemson House 1 mile from Campus!
4.93 out of 5 average rating, 226 reviews
Robin’s Nest- Cottage in the Woods
4.98 out of 5 average rating, 123 reviews
5 BR/5BA house in the heart of Clemson
4.97 out of 5 average rating, 112 reviews
Fisher's Paradise on Lake Saluda w Boat Ramp
4.9 out of 5 average rating, 162 reviews
Adjacent to Dawson Park/1 mile from Clemson Univ
4.85 out of 5 average rating, 309 reviews
Lakefront Paradise w Private Dock & Stunning Views
4.9 out of 5 average rating, 346 reviews
Basement apartment in Pendleton w/ sep. entrance
4.88 out of 5 average rating, 139 reviews
Lake Hartwell house w/ dock 2 miles from Clemson.
4.96 out of 5 average rating, 167 reviewsPet-friendly home rentals with a pool

Renfrow's Retreat
4.96 out of 5 average rating, 195 reviews
Lakeside Haven on Lake Keowee
5.0 out of 5 average rating, 42 reviews
Heron's Roost
4.99 out of 5 average rating, 95 reviews
Gated Townhouse in Clemson with Pool and Gas Grill
4.94 out of 5 average rating, 67 reviews
Lake Keowee Loft Cabin + Walkable Dock Access
4.86 out of 5 average rating, 29 reviews
Lake Keowee: Pools & Spa, Game Room, Golf, Clemson
5.0 out of 5 average rating, 81 reviews
Keowee Key, Entire Condo, 2 Bedrooms
4.97 out of 5 average rating, 30 reviews
Cozy Keowee cabin retreat in Six Mile
5.0 out of 5 average rating, 13 reviewsPrivate, pet-friendly home rentals

Mountain Cabin on Creek at Jocassee Gorge.
4.91 out of 5 average rating, 453 reviews
Charming cottage on a Family Farm.
4.96 out of 5 average rating, 156 reviews
New! Riverfront Tiny Home - Downtown Greenville SC
4.91 out of 5 average rating, 267 reviews
Readers Retreat: 10 min from Greenville downtown!
4.86 out of 5 average rating, 243 reviews
Hartwell Escape 6 mi to Clemson Beautiful views
4.94 out of 5 average rating, 134 reviews
Woods Retreat atTable Rock
5.0 out of 5 average rating, 52 reviews
Whispering Willow Lodge
4.96 out of 5 average rating, 23 reviews
Log Cabin, Table Rock Views, Pet Friendly
5.0 out of 5 average rating, 92 reviewsDestinations to explore
- Guesthouse rentals Pickens County
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- Rentals with lake access Pickens County
- House rentals Pickens County
- Family-friendly rentals Pickens County
- Tiny house rentals Pickens County
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- Rentals with a kayak Pickens County
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- Private suite rentals Pickens County
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- Pet-friendly rentals South Carolina
- Pet-friendly rentals United States
- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Table Rock State Park
- River Arts District
- The North Carolina Arboretum
- Black Rock Mountain State Park
- Chimney Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Devils Fork State Park
- Harrah's Cherokee Center - Asheville
- Lake Lure Beach and Water Park
- DuPont State Forest
- Chattooga Belle Farm
- Bon Secours Wellness Arena
- The Orange Peel
- Saint Paul Mountain Vineyards
- Biltmore Estate Winery
- Jump Off Rock
- Woolworth Walk
- Fred W Symmes Chapel
- French Broad River Park
- Falls Park On The Reedy





