
Family-friendly vacation rentals in Pickens County
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Pickens County
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Pickens County family-friendly rentals
Family-friendly home rentals with a hot tub

Lazy Bear Retreat by the Creek

Keowee Key Luxury Condo - Stunning Views!

Jocassee Gorge Mountain Lodge on creek-Waterfront

The Rustic Rectangle

Destination Keowee

5 Mins To Clemson + Hot Tub + Game Room + 5 Kings!

Napaw Mountain Log Cabin~Magical Mt.Top Experience

Lake Keowee, Waterfront Cabin, 2-Story Dock!
Family- and pet-friendly home rentals

Comfy, cozy duplex apt in old home downtown Easley

New! Riverfront Tiny Home - Downtown Greenville SC

Lakefront modern private guest suite 6mi to DT

Comfort & Convenience Close to Campus

Glamping on the Homestead

Hartwell Escape 6 mi to Clemson Beautiful views

The Cozy Cottage

Deer Creek Farm and Properties, LLC
Family-friendly home rentals with a pool

Perfect Tigertown Condo

4br/2ba Great location in heart of Clemson

Sports Basement

Lakeside Haven on Lake Keowee

123 Game Day Ready

Renfrow's Retreat

Beautiful Lake Keowee Condo with great Amenities

Fall Prices @ Carolina Oasis-Pets FREE!-Sleeps 6+
Destinations to explore
- Cabin rentals Pickens County
- Rentals with a washer and dryer Pickens County
- Rentals with breakfast Pickens County
- Waterfront rentals Pickens County
- Fitness-friendly rentals Pickens County
- Rentals with a hot tub Pickens County
- Apartment rentals Pickens County
- House rentals Pickens County
- Rentals with a kayak Pickens County
- Pet-friendly rentals Pickens County
- Rentals with outdoor seating Pickens County
- Condo rentals Pickens County
- Rentals with a fire pit Pickens County
- Rentals with pools Pickens County
- Private suite rentals Pickens County
- Rentals with a fireplace Pickens County
- Rentals with lake access Pickens County
- Rentals with a patio Pickens County
- RV rentals Pickens County
- Family-friendly rentals South Carolina
- Family-friendly rentals United States
- Blue Ridge Parkway
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Tugaloo State Park
- Chimney Rock State Park
- Tallulah Gorge State Park
- Mountaintop Golf & Lake Club
- Table Rock State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Maggie Valley Club
- Jump Off Rock
- Biltmore Forest County Club
- Victoria Valley Vineyards
- Vineyards for Biltmore Winery
- Old Edwards Club
- French Broad River Park
- Woolworth Walk
- Thomas Wolfe Memorial
- Discovery Island