Family-friendly vacation rentals in South Carolina

Find and book unique family-friendly homes on Airbnb

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Popular amenities for South Carolina family-friendly rentals

Family-friendly home rentals with a hot tub

Family- and pet-friendly home rentals

Family-friendly home rentals with a pool

Guest favorite

Guesthouse in Lexington

4.94 out of 5 average rating, 247 reviews

Come Pause and Relax!

May 16 – 23

€ 154 per night
Guest favorite

Condo in Myrtle Beach

4.97 out of 5 average rating, 235 reviews

Bright, airy, 3-BR, on golf course sleeps up to 6

Jan 7 – 14

€ 112 per night
Guest favorite

Villa in Hilton Head Island

4.92 out of 5 average rating, 330 reviews

Direct Ocean Front S. Forest Beach

Feb 5 – 12

€ 189 per night
Guest favorite

Home in Saint Helena Island

4.99 out of 5 average rating, 108 reviews

The Hampton House

Nov 7 – 14

€ 872 per night
Guest favorite

Condo in Hilton Head Island

4.85 out of 5 average rating, 234 reviews

Charming Sea Pines Villa with View on Hilton Head

Apr 21 – 28

€ 162 per night
Guest favorite

Condo in Myrtle Beach

4.96 out of 5 average rating, 177 reviews

Beautiful 1 B/R Ocean Front- Away from the Crowds

Mar 20 – 27

€ 200 per night
Guest favorite

Townhouse in Hilton Head Island

4.98 out of 5 average rating, 107 reviews

Beachfront Resort! Designer 2/2 Lagoon + Golf View

Feb 13 – 20

€ 324 per night
Guest favorite

Apartment in Johns Island

4.95 out of 5 average rating, 204 reviews

Sailors Rest: Heated Pool & Sauna, Johns Island

Mar 12 – 19

€ 241 per night

Destinations to explore