
House vacation rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool

Luxury beachfront villa!

Mountain Retreat: Peaceful & Private Escape

Dream house with beach access

Mediterranean House Punta Chame

Charming Oceanfront Coronado Pool House

Poolside Paradise in Santa Clara

Beautiful beach villa

The Dream of Playa Coronado
Weekly house rentals

Private Mountain Escape El Valle

Casa Colibrí - modern house in the green

Casa Verde in Volcán - Peaceful Oasis on the River

Jungle House in Playa Bluff- Casa Laurel

" Casa Esmeralda: Spacious and ideal for families"

Spacious Home with Lovely Pool, 2bdrm

CASA STARE - Oceanfront! Beach/Jacuzzi/Surfing

Bay Of The Floating Palms - Beach Front Home
Private house rentals

Family home in Gamboa next to the Canal

Oceanview loft with large private terrace

PIPA BEACH | Oceanfront with Beach Access

BirdHouse@ Gamboa Panamá Canal

Natural, ecological and comfortable apartment

Entire house with private pool facing beach !

Casa Coco - Beautiful Mountain Villa With AC

Custom Jungle Home by the Beach
Destinations to explore
- Lakehouse rentals Panama
- Family-friendly rentals Panama
- Rentals with a fireplace Panama
- Shipping container rentals Panama
- Rentals with a patio Panama
- Tiny house rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Treehouse rentals Panama
- Rentals with a fire pit Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a sauna Panama
- Apartment rentals Panama
- Rentals with an accessible height bed Panama
- Condo rentals Panama
- Bed and breakfasts Panama
- Cottage rentals Panama
- Aparthotel rentals Panama
- Hotel rentals Panama
- Loft rentals Panama
- Boutique hotel rentals Panama
- Pet-friendly rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Townhouse rentals Panama
- Bungalow rentals Panama
- Beach house rentals Panama
- Waterfront rentals Panama
- Rentals with lake access Panama
- Rentals with pools Panama
- Rentals with breakfast Panama
- Rentals with beach access Panama
- Island rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Farmstay rentals Panama
- Boat rentals Panama
- Villa rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Dome rentals Panama
- Fitness-friendly rentals Panama
- Rentals with a home theater Panama
- Smoking-friendly rentals Panama
- Chalet rentals Panama
- Nature eco lodge rentals Panama
- Rentals with a hot tub Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama