Hotel vacation rentals in Panama

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Panama

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Superhost

Hotel in La Enea

4.82 out of 5 average rating, 11 reviews

Private apartment with pool/beach access!

Looking for a private apartment with pool and beach access? The apartment has a queen size bed, bunk bed, and sofa bed with private bathroom. The 2nd floor balconies have pool/ocean views. The apartment is located at Playa Guarare, but is only a 20 minute drive to Las Tablas and 35 minutes to Chitre. On-site restaurant can provide daily meals. 2 minute walk to the beach and 3 minute walk to the port where you can hire a boat for fishing/whale watching. Hammocks and picnic tables available too!

Aug 11 – 18

€ 46 per night

Guest favorite

Boutique hotel in Bajo Boquete

5.0 out of 5 average rating, 17 reviews

The Residence - Colibri Room

Just a 10 minute walk to downtown Boquete this modern & contemporary designed room is located in an extraordinary tastfully furnished mansion. The beautiful terrace with a natural waterfountain is surrounded by gorgeous green areas inside a birdparadise in the higlands of Panama. Cozy furnished room (Queen-Size/Orthopedic mattress) with private bathroom. Impressive huge lobby area with different sitting areas. Big shared kitchen, dining area, free parking, fast Wifi, cable TV, Netflix, Spotify

Sep 10 – 17

€ 67 per night

Superhost

Nature lodge in Bastimentos Island

5.0 out of 5 average rating, 4 reviews

Dolphin Serenity - Tropical Suite with Pool

Indulge in tropical luxury at Dolphin Serenity, a two-story suite with a plush king bed. Our eco-lodge features a pool with panoramic views and family rooms. Our Lodge invites you to an unique experience—where boutique elegance meets B&B warmth. Unwind in comfort, surrounded by nature. Rooms offer free WiFi, private bathrooms, and terraces. Enjoy daily continental, American, or vegetarian breakfast. Exclusively for adults, this is your invitation to serenity. Book now for an exclusive escape.

Dec 2 – 9

€ 238 per night

Guest favorite

Hotel room in Bocas del Toro Province

4.86 out of 5 average rating, 111 reviews

Cozy Loft Hideaway with Double Bed

Welcome to our tropical paradise, where Caribbean vibes meet cozy comfort at our Bed & Breakfast! Get ready for sunsets that'll take your breath away, marine life marvels, and breakfast bliss on our breezy terrace. Tucked just outside the hustle of Bocas Town, we're your chill-out haven! Grab one of our bikes and pedal your way through town, or hop on a kayak for a watery adventure! Oh, and we're strictly for the over 18 crowd, 'cause we know how to keep it cool and classy. 🌅🌴🚴‍♂️🚣‍♀️🍳

Nov 17 – 24

€ 58 per night

Superhost

Hotel in Playa Coronado

4.85 out of 5 average rating, 20 reviews

Your spot away from home

You’ll be charmed by this adorable place to stay. This suite has a beautiful pool view, walking distance from one of the top Golf Courses in Panama, and close to the beach. A great place to relax and connect with the nature while you get pampered with all the resort services. Four restaurants, bar, gym, beach club, tennis, kids club, room service are some of the options that you can add to your stay. The suite includes high-speed WiFi connection, Smart TV, Kitchenette, and safety box.

Jul 9 – 16

€ 100 per night

Guest favorite

Hotel room in PA

4.91 out of 5 average rating, 23 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Jul 2 – 9

€ 91 per night

Superhost

Boutique hotel in PA

4.9 out of 5 average rating, 29 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Feb 1 – 8

€ 179 per night

Guest favorite

Hotel room in Colón Island

4.92 out of 5 average rating, 24 reviews

Oceanview Suite 2 - Bird Island Bungalows

Bird Island Bungalows is a hidden, secluded beach hotel surrounded by pristine private beaches, jungle and a 3.5ha lush tropical garden. From breathtaking sunsets from our 360 degree view roof top bar, silent meditation on our oceanview yoga deck, kayak tours to the bird watcher's paradise Bird Island to educational jungle walks to explore all the unique tropical flora and fauna - there is something for everyone or you just enjoy the beautiful silent sounds of nature and waves.

Jul 19 – 26

€ 113 per night

Superhost

Nature lodge in Taboga Island

4.91 out of 5 average rating, 54 reviews

Eco Lodge Garden Room 5 Oceanview Plunge Pool

Experience Cerrito Tropical Eco Lodge. Relax. Enjoy our refreshing plunge pool. Natural hillside location, interpretive garden. Jaw dropping oceanview from pool/deck (pool chairs, UV umbrellas). Walk to the beach. Comfortable ground floor room with bathroom, airconditioning, free Wifi and local TV. Exterior oceanview /gardenview balcony. Birdwatchers can spot up to 124 species recorded on Taboga. Artisanal pizza made onsite. Local taxes 10%. No pets in the Garden Rooms.

Jul 12 – 19

€ 76 per night

Guest favorite

Nature lodge in Bastimento

4.92 out of 5 average rating, 36 reviews

The Firefly B&B oceanfront bungalow w/ pool

Our b&b is a little off the beaten path but we love it that way. Listing is for one of our two private, oceanfront bungalows. We can let you know which one is available at time of booking. We are an eco lodge & describe our vibe as "hip, rustic beach house". Our rooms are fan cooled & have in room safes. Pool is shared by all five rooms. Breakfast is included. If a "resort" or 4 star place is your vibe, we are probably not for you :) We accept guests 15 and up.

Jul 13 – 20

€ 183 per night

Superhost

Hotel in Las Lajas

5.0 out of 5 average rating, 9 reviews

Beach Apartament Villa Deluxe

Disfruta de una estancia inolvidable en los apartamentos Villa Deluxe de playa Las Lajas. Estos acogedores apartamentos te brindan comodidad y estilo, con vistas espectaculares y un acceso directo a la playa. Relájate en su balcón privado o sumérgete en la piscina tropical para refrescarte. Con una ubicación privilegiada y servicios de primera clase, los apartamentos Villa Deluxe son el lugar perfecto para disfrutar de unas vacaciones de ensueño.

May 2 – 9

€ 83 per night

Guest favorite

Casa particular in Bocas del Toro

4.96 out of 5 average rating, 83 reviews

Urania House

Casa con hermosa vista al mar en donde puedes disfrutar de bellos atardeceres mientras se mece en las hamacas del balcon. La casa consta de tres amplias habitaciones, dos baños con agua caliente, Sala, comedor, cosina, terraza y balcon. La casa esta completamente equipada y amueblada para su comfort; TV cable, Internet-wifi.

Jun 2 – 9

€ 83 per night