Hotel vacation rentals in Panama

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Top-rated hotel rentals in Panama

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

The exterior of the mansion is showcased, featuring large glass windows and lush greenery. Vibrant flowers and neatly manicured hedges are present in the foreground, enhancing the natural beauty of the structure. A distinct stone pathway leads to the entrance, contributing to the inviting ambiance.

Hotel room in Boquete

4.97 out of 5 average rating, 38 reviews

The Residence - Bella Vista Suite

This Impressive, extravagant, light flooded Suite with breathtaking view to the Baru Volcano is located just a 10-minute walk from the center of Boquete. Modern and contemporary style with a high sense of detail, located in the second floor of an extraordinary mansion. Luxurious 80m² suite (King-Size/Orthopedic mattress) with spacius private bathroom, huge walkin closet, private full equipped kitchenette, panoramic window, 2 air conditioners, free parking, fast Wifi, cable TV, Netflix, Spotify.

Guest favorite

A spacious bedroom features a wooden bed with a blue patterned blanket. Large windows offer views of the lush greenery outside. A wooden desk with a chair is situated nearby, and warm hardwood flooring complements the natural light that fills the room.

Hotel room in PA

4.9 out of 5 average rating, 29 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Top guest favorite

A wooden table is set with bowls of vibrant fruit topped with flowers, alongside two small cups and mugs. A French press coffee maker is included. The background features tall greenery and palm trees visible through a screened porch.

Hotel room in Bastimentos Island

4.95 out of 5 average rating, 64 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Superhost

A green and white striped picnic blanket is spread on the grass, with two individuals seated on it. In the background, tropical plants and vibrant flowers create a lush setting. They are holding drinks, enjoying a relaxed moment amidst nature.

Private room in Panamá Oeste

5 out of 5 average rating, 3 reviews

Iwanna Green Ecolodge Room with Private Bathroom

Descubre tu oasis eco-amigable en el corazón de un hermoso entorno natural. Nuestra habitación con baño privado ofrece: Cama Full más sofá-cama Full Baño amplio, privado, con amenidades eco-amigables Ventanas con vista al jardín, ideal para relajarte Wi‑Fi gratuito de alta velocidad Desayuno saludable incluido (tostadas, huevos, frutas de temporada / café y más ) Espacios comunes: terrazas, piscina, espacios para descanso y más

Superhost

An outdoor seating area features wooden barstools and dining tables, situated beneath a covered patio. Natural light filters through, casting soft shadows on the polished floor. Lush greenery is visible in the background, enhancing the tranquil ambiance of the space.

Hotel room

4.94 out of 5 average rating, 18 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Guest favorite

A spacious living area is enhanced by natural light from large windows, showcasing a comfortable seating arrangement with a sleek couch and armchairs. A modern coffee table is centered with books and decorative items. A dining table is set nearby, offering a view of the greenery outside.

Private room in Panamá

4.82 out of 5 average rating, 22 reviews

Desk & Dream Room

Disfruta de la comodidad de este alojamiento tranquilo y céntrico en el corazón de San Francisco, tiene escritorio dentro de la habitación para trabajar o estudiar en un ambiente relax, con las demás comodidades incluyendo televisor led HD de 32" Justo en la calle de al lado está el super mercado, farmacia al frente, restaurantes, tiendas de chinitos, panaderías, paradas del metro bus cercanas.

Guest favorite

A wooden terrace extends over calm waters, adorned with lounge chairs and thatched-roof umbrellas. Soft lights create a serene ambiance as the sun sets in the background, reflecting warm hues on the water's surface.

Hotel room in Bocas del Toro

4.99 out of 5 average rating, 68 reviews

BarrBra / Double Bed / Priv. Bath. / Ac

- house built right over the Caribbean sea - bedroom with double sized bed & balcony - private bathroom (hot water shower) - air conditioning included - a la carte breakfast included (between 8 - 9:30 a.m.) - guest kitchen - sunset orientated (yes, we're facing west! :)) - ocean access from our private dock - in-house kayak, bike and snorkel gear rentals - gay-friendly place

A black scorpion is positioned among dried leaves and foliage. Its prominent pincers and segmented body are clearly visible, blending subtly with the natural surroundings. The texture of the leaves and the scorpion's surface can be observed, illustrating a typical forest floor habitat.

Nature lodge in Darién Province

4.7 out of 5 average rating, 20 reviews

La Chunga

La Chunga is in a difficult access indigenous community without electricity or roads. Come see this gem of a community and the indigenous way of life. You’ll love this place because of the nature walks, the wildlife, the gastronomy, and the people. We have a number of guided tours and adventures. My place is good for adventurers trying to see something new and exciting.

Guest favorite

A flowing river cuts through lush greenery, flanked by buildings on either side. The mountains rise in the background, partially covered by clouds. Blue skies with scattered clouds create an appealing contrast to the earthy tones of the water and surrounding foliage.

Hotel room in Boquete

4.78 out of 5 average rating, 133 reviews

Private Room in Boquete

Enjoy the simplicity of this quiet and central accommodation in town, just a few steps from grocery stores, restaurants, bars, coffee shops, with easy access to public or private transportation. This room has a comfortable bed, private bathroom with hot water ample space, the kitchen is perfectly equipped to share with two other rooms, the garden is beautiful.

Top guest favorite

Tall palm trees frame a view of the ocean, with a green lawn leading down to the water. Colorful buildings are visible on either side, creating a serene environment. The sky is bright and clear, enhancing the relaxed atmosphere of the space.

Private room in Santa Catalina

4.95 out of 5 average rating, 20 reviews

Casa Manila Doble Room with terrace

Welcome to our calm place in front of the ocean. The place is perfect for relaxing on your private terrace and offers breathtaking views of the pacific ocean. In our freshly renovated rooms with A/C you can enjoy a cold breeze after a sunny day. At the end of the day you will be surprised by the best sunset in Santa Catalina.

Guest favorite

A spacious patio area features multiple black wicker chairs arranged along a colorful stone pathway. The outdoor space offers unobstructed views of the sandy beach and ocean beyond, with a wooden railing providing a sense of enclosure. People can be seen enjoying the beach in the distance.

Hotel room in Las Tablas Abajo

4.82 out of 5 average rating, 79 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.

Casa particular in Contadora Island

5 out of 5 average rating, 3 reviews

Ocean Front House on exclusive Contadora Island

Whale season has begun! July-October 🐳 Welcome to your paradise on Contadora Island, a hidden gem in the heart of Panama's Pearl Islands. This stunning Ocean Front house offers unparalleled views of the turquoise waters providing the perfect escape for those seeking both tranquility and adventure.