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Panama vacation rentals

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Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite
Apartment in Panamá
Chic Studio in Casco Antiguo - View to Main Plaza
Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.
Individual Host
Guest favorite
Condo in Panama City
Park View Luxury Apartment
This apartment provides the perfect comfort while travelling in Panama for business or pleasure. Enjoy a wonderful stay in this beautiful apartment in a great location, the building is new, it features gym, pool, hot tub and beautiful views of the city, pacific ocean. It is 2 blocks away from a giant recreational park called Parque Omar which happens to be the First Lady's Office so it is very well guarded, featuring free dance zumba and yoga classes everyday. Make this place your HOME.
Individual Host
Guest favorite
Apartment in Panamá
Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.
Individual Host

Popular amenities for Panama vacation rentals

Panama homes

Guest favorite
Home in Bocas del Toro District
Orange House - Over The Water Rentals
Professional Host
Guest favorite
Home in Panamá
Private Studio 10 Min from the airport !
Individual Host
Superhost
Home in Vista Mar Golf, Beach & Marina
Luxurious Beach House - Private Pool Golf & Marina
Individual Host
Superhost
Home in Bocas del Toro Province
Casa Clearwater... Your Caribbean Dream
Individual Host
Guest favorite
Home in Playa Venao
Beautiful Home Directly on Playa Venao Sleeps 8-10
Individual Host
Guest favorite
Home in Taboga Island
Casa Rosie - Taboga dream home
Individual Host
Guest favorite
Home in Bajo Boquete
El Paraiso - Casa Blanca - Bajo Boquete
Individual Host
Superhost
Home in El Valle de Antón
Casa Antares
Individual Host
Guest favorite
Home in Las Colinas de Caceres de Arraijan
Tropical Haven with Yoga Platform
Individual Host
Guest favorite
Home in Pedasí
3 min to Pedasi, 5 min to the Beach, Private Pool!
Individual Host
Guest favorite
Home in Panama
Villa Isabella in Coronado Beach Panama
Individual Host
Guest favorite
Home in Panamá
Golden Space | By Paradox
Individual Host

Panama condominium rentals

Guest favorite
Condo in Panama
Patty’s Cozy & Quiet Studio with K-bed in Casco
Individual Host
Guest favorite
Condo in Panamá
Cozy two bedroom apartment
Individual Host
Superhost
Condo in Panamá
Cozy Unit with Balcony in Santa Ana, Casco Viejo
Individual Host
Guest favorite
Condo in Panamá
Luxury apartment in the heart of Casco Antiguo
Individual Host
Guest favorite
Condo in Nueva Gorgona
Fabulous Beach Friendly-Ph Royal Palm-Gorgona
Individual Host
Guest favorite
Condo in Chame
Exclusive Beachfront apartment 1Hour from Pma City
Individual Host
Guest favorite
Condo in Buenaventura, Río Hato
Modern | Marina View Balcony | Pool | Sleeps 6
Professional Host
Guest favorite
Condo in Panamá
Los Diamantes "Terraza" - ideally located
Professional Host
Guest favorite
Condo in Panama City
Isthmus Concept Apartment
Individual Host
Superhost
Condo in Panama City
Beautiful apartment with ocean views.
Individual Host
Guest favorite
Condo in Punta Pacifica
5 stars, Apartment Vista al Mar
Professional Host
Guest favorite
Condo in El Cangrejo
Spacious Executive 37th-Floor Quiet Apartment
Individual Host

Other great vacation rentals in Panama

Guest favorite
Loft in Panamá
Loft Studio | By Paradox
Individual Host
Guest favorite
Apartment in Panamá
Angie’s Place Cozy n Comfy in the ❤️ of #CascoViejo
Individual Host
Guest favorite
Apartment in Panamá
Superb Apartment In The Center Of Panama City
Individual Host
Guest favorite
Apartment in Panamá
Full apartment in Panama
Individual Host
Guest favorite
Apartment in Panamá
Tropicool Loft w/rooftop steps from Casco
Individual Host
Guest favorite
Apartment in Panama City
280 View of Cinta Costera/Casco/Canal WIFI 500mbps
Individual Host
Guest favorite
Apartment in Panama City
Free bottle Wine -elegant start & Self-check in
Individual Host
Guest favorite
Apartment in Panama City
Cozy Bay Front Apt With Infinity Pool & Views
Individual Host
Guest favorite
Apartment in Panamá
Top Trump Residence, in the Sky
Individual Host
Guest favorite
Apartment in Panamá
Yoo Panama waterfront 36th floor
Individual Host
Guest favorite
Apartment in Panamá
Entire home with parking
Individual Host
Guest favorite
Apartment in Panama City
Stunning views from the clouds!
Professional Host

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

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