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Boutique hotel vacation rentals in Panama

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Panama

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Superhost
A furnished bedroom features a spacious bed with white linens, flanked by bedside tables with lamps. Soft artwork adorns the wall above, while a bench rests at the foot of the bed. A cozy throw drapes over the bench, completing the inviting arrangement.
Hotel room in Boquete
4.89 out of 5 average rating, 114 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Guest favorite
A spacious bedroom features a wooden platform bed with a blue patterned mattress. Large glass doors open to a private patio, surrounded by lush greenery. Two chairs are positioned on the terrace, and a colorful framed artwork adorns the wall near a window.
Hotel room in PA
4.9 out of 5 average rating, 30 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Superhost
Hotel room in PA
4.91 out of 5 average rating, 35 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Guest favorite
The bungalow features a screened-in porch, framed by lush greenery and colorful plants. Warm sunlight casts shadows across the wooden structure, creating a serene and inviting atmosphere amidst the surrounding foliage.
Hotel room in Bastimentos Island
4.95 out of 5 average rating, 65 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Superhost
A bright and airy bedroom features a spacious bed centered against a muted wall. Two bedside lamps provide soft illumination, while three framed marine-themed artworks are displayed above the bed. Large windows allow natural light to fill the room, enhancing the relaxed ambiance.
Hotel room in Playa Venao
4.8 out of 5 average rating, 5 reviews

Deluxe King Ocean View @ Villa Marina Playa Venao

Amamos el océano tanto como tú. Por eso hemos creado el lugar perfecto para que disfrutes de las olas y de todo lo que el Pacífico panameño tiene para ti en las playas de Pedasí. Villa Marina Lodge es un lugar único en su categoría. Ubicado en Playa Venao, un paraíso internacional del surf, ofrece habitaciones cómodas y amenidades de primera para que tu viaje a la playa sea siempre una experiencia especial. Un lodge, a diferencia de un resort, es más relajado, casual y acogedor.

Superhost
The room features an earthy decor with a queen bed flanked by two mounted shelves. A mini fridge is positioned next to a wooden side table. Natural light filters through the sheer curtains, creating a calming atmosphere.
Hotel room in Playa Venao
5 out of 5 average rating, 8 reviews

Olas Room - Quiet, Second Floor w/ Queen bed

Olas Room is a peaceful, economical, 2 person room located at the stunning El Sitio Hotel. Here you will find a comfortable clean, queen bed, a mini fridge in your room to keep your drinks cool and a bathroom equipped with hot and cold water to wash away the sand and salt after a day in the sun. Your room is steps away from an incredible pool/lounge area with a stunning view of the ocean. *A 10% tax will be collected separately as Airbnb do not collect tax on behalf of host.

A spacious bed is positioned centrally in the room, adorned with neutral-toned bedding. Two ottoman-like stools are placed at the foot of the bed. A laptop is being used on the bed, with soft lighting emanating from lamps on either side, creating a cozy ambiance.
Hotel room in San Carlos
4.78 out of 5 average rating, 129 reviews

B) Beach, surf and Relax with King size bed

Manglar Lodge is a small beach Hotel located at El Palmar beach on the Pacific coast on the town of San Carlos, If you like nature and comfort, you'll enjoy your stay at Manglar Lodge We are small beach hotel that offers the visitor four cozy and clean rooms, WiFi, restaurant (open form 8.30am until 8pm) with great food and a great selection of craft beer and The Room is on a 1 floor you have to walk up the stairs

Guest favorite
The villa is situated amidst lush greenery, showcasing a modern design that blends with the surrounding jungle. Spacious outdoor areas are visible, with seating arrangements under the shade of trees, inviting a relaxed atmosphere for guests to enjoy their surroundings.
Hotel room
4.95 out of 5 average rating, 20 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Guest favorite
A wooden plaque with the name 'Andy 1' is displayed prominently. The name is painted in black cursive lettering on a light wood background. A few elegant cream-colored flowers are attached to the top corner of the plaque, adding a decorative touch.
Hotel room in Punta Chame
4.89 out of 5 average rating, 9 reviews

Andy 1, room in a house with beach access

The Andy 1 room is located on a mezzanine accessed by stairs from the first floor of the houseboat. The room sleeps three people, has a queen bed and a single bed. It has its own private bathroom in the room, a desk, a television, and has air conditioning and internet access. Guests in this room have access to a kitchen located within the lot, a short distance from the houseboat.

Guest favorite
A charming stone structure is surrounded by lush greenery in this tranquil setting. Soft lighting enhances the architectural details, while the inviting garden area features neatly trimmed hedges and flower beds. A patio area can be seen beside the main building, perfect for outdoor relaxation.
Hotel room in El Valle de Antón
4.8 out of 5 average rating, 35 reviews

Medieval Suite Nature & Art

The Corte del Re is a tourist structure composed of a set of suites with a medieval theme (macabre art) immersed in the woods where art and nature blend in the heart of the Anton Valley. A few steps from the center are equipped with all comforts and have a park, pool, lake with Koi carpe and parking. They are suites and therefore do not have a kitchen.

Guest favorite
A close-up view of vibrant purple bougainvillea flowers is presented alongside a well-maintained pathway, leading to a charming building with arched windows and a wooden front door. Green foliage frames the entrance, enhancing the welcoming atmosphere.
Hotel room in Panamá
4.86 out of 5 average rating, 44 reviews

Private rooms Sofia's B&B Hostal Boutique

Boutique hostel-style accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The rate shown by Airbnb for your reservation is for 2 guests per room, i.e., guests will need to share beds and/or rooms. If you require a special room layout for your group, please contact the host first, as the rate may vary.

Guest favorite
Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.
Hotel room in Panamá
4.85 out of 5 average rating, 107 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

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