House vacation rentals in Muscle Shoals

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Top-rated house rentals in Muscle Shoals

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Superhost
A modern living space features a ceiling fan and a wall-mounted television displaying streaming service options. A woven chair is positioned next to a wooden side table, with a decorative rug laid on the polished hardwood floor. Light-colored walls enhance the ambiance.
Home in Florence
4.89 out of 5 average rating, 172 reviews

Mid-City Modern - Super Convenient to Downtown

Whether you are travelling alone or are a group of up to four you will find Mid-City Modern comfy and cozy! Enjoy all Florence has to offer from your home base with us. Mid-City Modern is a newly renovated Mid-Century home, Aug 19', that has been brought beautifully into the modern era. Conveniently located in the heart of Florence and allows easy access to everything our city has to offer. Located in a quiet established neighborhood with an open lot and a small creek directly across the street.

Superhost
A compact dining area features a wooden table set for two and surrounded by simple wooden chairs. Light enters through two windows, highlighting the neutral tones of the walls. A clock and artwork adorn the walls, adding subtle character to the space.
Home in Florence
4.84 out of 5 average rating, 273 reviews

Close to Hospital, Eastside Bungalow, (Dog + Fee)

A cozy spot during your stay for work, transition, or leisure? The Eastside Bungalow is the perfect match, just 4 blocks from the North Alabama Medical Center! Nestled in a developing neighborhood, it offers a full kitchen including a drip coffee maker (we supply the coffee), living/dining area, bath w/shower, Smart TV, Wi-Fi, and dogs welcome with a fenced backyard. Conveniently close to the hospital, conference center, and 5 minutes to shopping, dining, and Florence Harbor. Book now! 🏡🐾

Top guest favorite
A welcoming living area showcases a cozy sofa facing a mounted television. A floor lamp and side table add a touch of style, while decorative accents bring warmth. Natural light streams in through a window, illuminating the wooden walls and enhancing the inviting ambiance.
Home in Muscle Shoals
5 out of 5 average rating, 223 reviews

Bass & Birdie of the Shoals

Kick back and relax in this calm, stylish space. Come enjoy beautiful sunsets on your private deck while relaxing in a hot tub or sitting around the fire pit. Enjoy this cozy retreat only 1 mile from RTJ golf course, and 3 miles to the closest boat ramp. This home offers a kitchen with a coffee bar and wine cooler, interior/exterior TV, spacious walk-in shower and claw foot tub. We also offer boat and RV utility hook ups. Enjoy a wide variety of eating and entertainment 10-15 minutes away.

Guest favorite
A stone firepit is positioned among gravel, surrounded by several wooden chairs. The serene lake can be seen in the background, along with lush green trees and a dock in the distance. The sky is filled with clouds and blue hues, reflecting a calm atmosphere.
Home in Muscle Shoals
4.89 out of 5 average rating, 111 reviews

Nice Lakeside near RTJ Golf Course w Puttng Green

Come enjoy the nature and beauty of this elegant, updated, and spacious lake home located only two miles from RTJ Golf Course. Fish off the pier while you enjoy the cozy firepit or putting green while watching the sunset over Wilson Lake. This 10 bed home has been carefully curated with your comfort and enjoyment in mind. TV's & WiFi are offered in every room, along with a well-equipped kitchen containing new appliances. Bring your friends and family to relax in Donegans Slough, Muscle Shoals.

Guest favorite
A partially enclosed porch features a rustic daybed with a light-colored patterned mattress. Brightly colored pillows are arranged on the bed, creating a comfortable seating area. The backdrop includes a scenic view of the lake and lush greenery, inviting relaxation.
Home in Tuscumbia
4.92 out of 5 average rating, 101 reviews

The Three Gulls - Pickwick Lake

Mostly remodeled 1960s ranch style home, 3 BR, two bath directly on lakefront about 5 miles west of Tuscumbia on Pickwick Lake in rural area. Home has 5 beds: one king, two doubles and two twins. Features include a spacious screened in porch with lake view and multilevel deck directly on main river. Small pier for swimming, or it may be used for securing boat. Closest boat launch site is Pride Landing, about 5 miles west of house. Double driveway offers plenty of parking space.

Guest favorite
A bright living room is showcased with dual dark sofas adorned with decorative pillows. A wooden coffee table sits centrally, featuring a plant and decorative items. Natural light enters through the sheer curtains, complementing the inviting red front door in the background.
Home in Florence
4.9 out of 5 average rating, 119 reviews

Cozy Home at 7 Points

Welcome to our charming rental in historic Florence, Alabama. Explore downtown's boutiques and eateries, UNA's campus, and McFarland Park's scenic beauty nearby. Cozy bedrooms, well-equipped kitchen, and a memorable stay await. Located just a stone's throw away from downtown Florence, UNA, and the Tennessee River, you'll be delighted to explore the vibrant streets lined with boutique shops, art galleries, and an array of delicious eateries as well as the University and park.

Superhost
A welcoming living area features a light-colored sofa adorned with decorative cushions, a small white coffee table, and a comfortable accent chair. Natural light filters through two windows, highlighting the refinished wooden flooring. A stylish light fixture hangs from the ceiling, adding a modern touch.
Home in Florence
4.91 out of 5 average rating, 252 reviews

The Mellow Mushroom

You'll love the Mellow Mushroom! The home is a beautifully decorated Boho style space located less than a mile from the University and Downtown! Whether you're in town for work or a vacation or just visiting friends and family this place will feel like home. We provide coffee and popcorn to save you a trip to the store, if you need anything though there is a Dollar General and Grocery Store less than a mile from the place. I offer instant booking. And self check-in for guests.

Top guest favorite
The image features a hot tub with bubbling water, surrounded by a stone patio. In the background, a dining area is seen with a table, four chairs, and a patio umbrella. Soft lighting enhances the ambiance, along with decorative planters placed nearby.
Home in Florence
4.98 out of 5 average rating, 260 reviews

Charming River Rock house/hot tub & backyard oasis

Embrace the charm of this renovated 2-bed, 1-bath River Rock house. Relax in the private backyard oasis with a hot tub, dining area, patio umbrella, heater, lighting, and a seasonal outdoor shower (shower closed Oct. - May). Ample off-street parking, perfect for boats and RVs. Security cameras are located outside with a monitor to view the cameras located in the laundry room. Minutes from downtown and Muscle Shoals, this retreat offers modern comfort in a convenient location.

Guest favorite
The exterior of the retreat features a charming white façade with decorative trim. A light purple front door welcomes guests, framed by large windows with flower boxes. A lush green lawn and a well-established tree enhance the serene outdoor setting.
Home in Florence
4.99 out of 5 average rating, 118 reviews

The Pine Spring Knoll

Welcome to the Pine Spring Knoll! This European inspired retreat offers a luxurious 2-bed, 1-bath experience with curated design touches throughout. Unwind and enjoy the private balcony, gather around the fire pit for a cozy evening under the stars, relax in the soaking tub, cuddle up in the living room with a book or watch your favorite movie. Experience the perfect blend of comfort and style in this charming getaway right in downtown Florence.

Top guest favorite
A comfortable sitting room features a light-colored sofa adorned with various textured cushions. A rustic coffee table is centered in the space, complemented by a decorative bowl. Natural light enters through large windows, enhancing the cozy seating arrangement and warm wooden accents.
Home in Florence
4.97 out of 5 average rating, 105 reviews

Sandstone Cottage in Downtown Florence

The Sandstone Cottage is located in downtown Florence, Alabama minutes away from the University of North Alabama, 7 points, and Court Street. It includes a sitting room, cozy den, spacious kitchen, 3 bedrooms, and 2 full baths, as well as a private backyard complete with a covered deck and outdoor seating. Kick back and relax in this newly renovated and styled home designed to provide a unique and relaxing space to enjoy the best of the Shoals!

Guest favorite
A spacious room features two twin beds adorned with neutral bedding, flanked by wooden nightstands and lamps. A small table sits between the beds. A light-colored area rug covers the floor, and a window provides natural light, complemented by wall-mounted lighting.
Home in Florence
4.78 out of 5 average rating, 130 reviews

Historic Court St Home steps from UNA and downtown

This home has a long and unique history dating back to the 1800's. It is practically on UNA's campus, just a 2 minute walk to Starbucks & Chick-fil-A to the north, and a 5 minute walk to the restaurants and shops of downtown Florence to the south. Upstairs, there are 2 bedrooms, 1 bathroom and a coffee nook with microwave and fridge. Downstairs there is more living space with a dining table and living room. New cleaning company as of 11/24!

Guest favorite
A well-lit bedroom contains two beds, one framed and the other a twin. Neutral bedding complements the warm wood flooring. Soft red curtains frame the window, while a small mirror and bedside table add functionality. A ceiling fan provides additional comfort.
Home in Florence
4.92 out of 5 average rating, 103 reviews

Button House- 7 Points.

This house is cute as a button! Welcome to our cozy and comfortable vacation home. We are located just minutes from the up-and-coming 7 Points area, downtown Florence, and University of Alabama. Muscle Shoals, Huntsville and other places of interest are just an easy drive away. Our home is the perfect place to relax and unwind after exploring North Alabama, located in a quiet neighborhood close to great restaurants and charming shops.

Popular amenities for Muscle Shoals house rentals

Quick stats about house rentals in Muscle Shoals

  • Total vacation rentals

    Explore 10 vacation rentals in Muscle Shoals

  • Nightly prices starting at

    Muscle Shoals vacation rentals start at € 78 per night before taxes and fees

  • Verified guest reviews

    Over 500 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Muscle Shoals vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Muscle Shoals rentals

  • 4.9 Average rating

    Muscle Shoals stays are highly rated by guests—averaging 4.9 out of 5!

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