Guesthouse vacation rentals in Mount Pleasant
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Top-rated guesthouse rentals in Mount Pleasant
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mount Pleasant guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
Dec 8 – 15
Guesthouse in North Charleston
5.0 out of 5 average rating, 110 reviewsThe Park Circle Clerestory Studio Guest House
Jun 20 – 27
Guesthouse in Mount Pleasant
4.85 out of 5 average rating, 218 reviewsClose to beach , downtown and Shem creek
Jun 4 – 11
Guesthouse in Charleston
4.93 out of 5 average rating, 708 reviewsCharleston's Coolest Neighborhood
Aug 8 – 15
Guesthouse in Summerville
4.98 out of 5 average rating, 642 reviews★Delightful guest house near historic plantations★
Oct 30 – Nov 6
Guesthouse in Charleston
4.95 out of 5 average rating, 331 reviewsThe White House of Avondale
Oct 13 – 20
Guesthouse in Ridgeville
4.82 out of 5 average rating, 212 reviewsPond House Bungalow at Natural Gathering Grounds
Oct 29 – Nov 5
Guesthouse in Charleston
4.91 out of 5 average rating, 647 reviewsIsland Oasis—Near Downtown
Oct 21 – 28
Guest house rentals with a patio
Guesthouse in Charleston
4.98 out of 5 average rating, 121 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Jan 13 – 20
Guesthouse in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
Oct 7 – 14
Guesthouse in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
Apr 13 – 20
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 25 reviewsCoastal Charm: Village Hideaway
Dec 14 – 21
Guesthouse in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
Aug 6 – 13
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 71 reviews*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
Aug 20 – 27
Guesthouse in Mount Pleasant
4.88 out of 5 average rating, 16 reviewsAdorable guest house with private backyard/patio
Sep 23 – 30
Guesthouse in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
Jun 18 – 25
Guest house rentals with a washer and dryer
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 253 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Feb 6 – 13
Guesthouse in Summerville
4.97 out of 5 average rating, 215 reviewsTiny Oak Cottage in Historic Downtown Summerville
Nov 7 – 14
Guesthouse in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
Jan 23 – 30
Guesthouse in Charleston
4.9 out of 5 average rating, 547 reviewsCute, Cozy, Charleston Cottage
Aug 12 – 19
Guesthouse in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
Oct 2 – 9
Guesthouse in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
Jul 14 – 21
Guesthouse in Charleston
4.99 out of 5 average rating, 141 reviewsLarge Guesthouse with Private Dock & Marsh Views
Dec 3 – 10
Guesthouse in Charleston
4.99 out of 5 average rating, 205 reviewsRedesigned suite! 12min to city, pet-friendly
Nov 14 – 21
Quick stats about guesthouse rentals in Mount Pleasant
Total rentals
60 properties
Popular amenities
Kitchen, Wifi, and Pool
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
5.7K reviews
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