House vacation rentals in Mesilla
Find and book unique houses on Airbnb
Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesilla house rentals
House rentals with a pool
Home in Las Cruces
4.93 out of 5 average rating, 266 reviewsCasita at the Mediterranean Palms Estate
Jul 25 – Aug 1
Home in Las Cruces
4.87 out of 5 average rating, 120 reviewsDesert Pool Oasis
Aug 13 – 20
Home in Las Cruces
4.94 out of 5 average rating, 174 reviewsPet Friendly Luxury Oasis With Pool and Hot-tub!EV
Mar 27 – Apr 3
Home in Las Cruces
4.97 out of 5 average rating, 37 reviewsCottage Noz
Feb 26 – Mar 5
Home in Las Cruces
4.96 out of 5 average rating, 72 reviewsDesert Oasis with Pool
Feb 5 – 12
Home in Las Cruces
5.0 out of 5 average rating, 60 reviewsLUXURy, Heated POOl, Sunset Views, Early Check-in
Oct 26 – Nov 2
Home in Las Cruces
5.0 out of 5 average rating, 15 reviewsDesert Paradise, with hot tub
Apr 11 – 18
Home in Las Cruces
4.95 out of 5 average rating, 19 reviewsNear Organ National Monument & NMSU Golf Course
Aug 8 – 15
Weekly house rentals
Home in Las Cruces
4.99 out of 5 average rating, 118 reviewsWelcome to Casa Stagecoach, kids and dogs welcome!
Jul 25 – Aug 1
Home in Las Cruces
4.99 out of 5 average rating, 120 reviewsHome in Las Cruces Casa de Flores Near NMSU
Jan 3 – 10
Home in Las Cruces
4.95 out of 5 average rating, 180 reviewsCozy & Comfortable New Mexico Home
Sep 14 – 21
Home in Las Cruces
5.0 out of 5 average rating, 141 reviews"Casa de Maíz" centrally located - close to NMSU
Aug 11 – 18
Home in Las Cruces
4.87 out of 5 average rating, 120 reviewsDarling Southwest style casita
Jul 25 – Aug 1
Home in Las Cruces
4.99 out of 5 average rating, 150 reviewsSunset Views, Gym, & Bball - Secluded 3BR/2BA Gem!
Aug 17 – 24
Home in Las Cruces
4.88 out of 5 average rating, 152 reviewsTuscan Villa Outdoor Living, Jacuzzi & Gym
Oct 19 – 26
Home in Las Cruces
4.91 out of 5 average rating, 140 reviewsExecutive Hills
Sep 9 – 16
Private house rentals
Home in Las Cruces
4.92 out of 5 average rating, 147 reviewsAdobe Loft with yard, free parking, pets welcome!
Aug 21 – 28
Home in Las Cruces
4.84 out of 5 average rating, 141 reviewsVIGIL-INN High Desert Escape in Quiet Neighborhood
Jun 1 – 8
Home in Las Cruces
5.0 out of 5 average rating, 12 reviewsQueen Suite at Josefina's in Mesilla Plaza
Jul 16 – 23
Home in Las Cruces
4.92 out of 5 average rating, 24 reviewsCharming Adobe Casita in Old Mesilla - near NMSU
Aug 29 – Sep 5
Home in Las Cruces
4.96 out of 5 average rating, 72 reviewsChic Downtown Bungalow Minutes from Old Mesilla
Jul 16 – 23
Home in Las Cruces
4.96 out of 5 average rating, 25 reviewsConway Cottage 5-1
Aug 18 – 25
Home in Las Cruces
4.96 out of 5 average rating, 56 reviewsSouthwestern Comfort Stay 2
Apr 9 – 16
Home in Mesilla Park
4.78 out of 5 average rating, 91 reviewsQuaint southwest home with old charm vibes
Jul 20 – 27
Quick stats about house rentals in Mesilla
Total rentals
20 properties
Wifi availability
20 properties include access to wifi
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
1.8K reviews
Nightly prices starting at
€ 56 before taxes and fees
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