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House vacation rentals in Mesilla

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Top-rated house rentals in Mesilla

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
An aerial view of a Pueblo Style home is presented, showcasing a serene pool surrounded by a spacious outdoor area. The home is set against a backdrop of rolling hills and a cloudy sky. Desert vegetation is seen throughout the landscape, enhancing the natural beauty.
Home in Las Cruces
4.97 out of 5 average rating, 151 reviews

Desert Oasis with Pool

Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Guest favorite
Home in Mesilla Park
4.94 out of 5 average rating, 145 reviews

Casita Conway 2

Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Top guest favorite
An outdoor seating area is highlighted by four Adirondack chairs arranged around a glowing gas fire pit. A stone wall forms the background, while a dining set is visible in the distance, with soft evening light creating a serene atmosphere.
Home in Las Cruces
4.96 out of 5 average rating, 137 reviews

Luxury Southwest Retreat

Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Top guest favorite
The exterior of a Southwestern home is showcased, featuring adobe-style architecture with a textured beige facade. A two-car garage is visible, along with a gravel front yard and desert landscaping, highlighted by rocks and sparse vegetation under a clear blue sky.
Home in Las Cruces
4.87 out of 5 average rating, 315 reviews

Casa Miranda, The Organ Mountains Looking House

Experience your clean, comfortable & spacious Southwestern home in Las Cruces, NM, now with a brand new refrigerated AC system. Your home has wonderful amenities: a fully stocked kitchen, washer/dryer, iron, comfortable beds (king & queen size), 65' flat screen TV in the living room with Wifi, secure two car garage, and a backyard with a breathtaking view of The Organ Mountains. Located minutes from both I-25/ US-70, easily get to downtown, Mesilla, NMSU, White Sands, and The Lincoln Forest.

Top guest favorite
A hot tub is situated under a wooden pergola, with warm water gently bubbling. The backdrop features an open sky transitioning to twilight, while cozy seating is arranged nearby on a grassy area, offering a tranquil outdoor space.
Home in Las Cruces
4.99 out of 5 average rating, 136 reviews

Modern Farmhouse Near Bike Path

Enjoy complete solitude and coveted NM sunset's from this fully equipped 3 Br + 2 Bth farmhouse with office. Just 10 minutes from the Historic Old Mesilla Plaza and Downtown LC, this newly built oasis with mountain views is both convenient and private. Directly behind the home lies Outfall Channel bike path, spanning 4.4 miles through urban and agricultural settings. Pet friendly yard, fit with patio, hot tub, firepit, and cornhole allows every opportunity to enjoy our remarkable SW skies.

Guest favorite
The historic adobe home is adorned with natural tones and rustic architecture. A welcoming entrance is framed by a decorative wrought iron gate, alongside a gravel pathway leading to the front door. Lush greenery and native plants enhance the inviting exterior.
Home in Las Cruces
4.94 out of 5 average rating, 222 reviews

Historic Adobe Home- Libélula (Dragonfly)

Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A ​5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

Superhost
The spacious living area features high ceilings with exposed wooden beams. Two plush sofas are positioned around a wooden coffee table, creating a comfortable seating arrangement. The open kitchen is visible in the background, showcasing wooden cabinetry and modern appliances.
Home in Las Cruces
4.86 out of 5 average rating, 305 reviews

Tuscan Villa Outdoor Living, Jacuzzi & Gym

This fully-furnished Tuscan style home is perfect for weekend getaways or longterm stays. With a jacuzzi and expanded outdoor living space the Greek-style Villa offers the comfort of home with a vacation vibe. Stream Netflix in the vaulted living room, soak in the outdoor hot tub, or enjoy your morning coffee lounging on the patio couch. This stylish space can be the romantic escape you're seeking or accommodate your group of 8. All this only minutes from all Las Cruces has to offer.

Guest favorite
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.94 out of 5 average rating, 349 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building is fully renovated with stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Guest favorite
An inviting outdoor space features a heated pool and spa surrounded by palm trees. The unique pool shape complements the natural stone walls, while the sunset sky adds a warm glow. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Home in Las Cruces
4.97 out of 5 average rating, 146 reviews

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Freshly remodeled luxury home in the heart of Las Cruces, located just 5 minutes from down town in a safe quite neighborhood! Enjoy local restaurants and bars just minutes away! Wood floors throughout the home, with granite countertops and brand new appliances!Massive open floor plan in the kitchen area with an 85 inch TV and surround sound system! Heated Pool and Spa for year round use! Pet friendly fully enclosed back yard! You will never want to leave this Luxury Oasis!

Guest favorite
Home in Las Cruces
4.9 out of 5 average rating, 114 reviews

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Top guest favorite
A spacious outdoor area showcases a desert landscape with gravel and low-lying plants. A large round table is accompanied by a bright red umbrella, offering shade. The casita's entrance features a patio with seating and a welcoming purple trim, enhancing the inviting exterior.
Home in Las Cruces
4.97 out of 5 average rating, 189 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Top guest favorite
An adobe-style home is displayed, featuring a gravel pathway leading to an entrance framed by wooden gates. Two turquoise chairs sit beside a small table under a budding tree. Planted flowers in bright pots add color to the exterior, enhancing the welcoming appearance.
Home in Mesilla
4.98 out of 5 average rating, 167 reviews

Sombra Del Valle in Historic Mesilla

Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Popular amenities for Mesilla house rentals

When is the best time to visit Mesilla?

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Avg. price€ 99€ 99€ 108€ 99€ 108€ 108€ 86€ 93€ 86€ 86€ 99€ 99
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Quick stats about house rentals in Mesilla

  • Total vacation rentals

    Explore 20 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at € 52 per night before taxes and fees

  • Verified guest reviews

    Over 1,970 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!

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