
Pet-friendly vacation rentals in Mesilla
Find and book unique pet-friendly homes on Airbnb
Quick stats about vacation rentals that are pet-friendly in Mesilla

Total vacation rentals
Explore 30 vacation rentals in Mesilla

Nightly prices starting at
Mesilla vacation rentals start at €34 per night before taxes and fees

Verified guest reviews
Over 2,920 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
30 of Mesilla vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated pet-friendly home rentals in Mesilla
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Ocotillo Casita in Historic Mesilla
Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Modern Farmhouse Near Bike Path
Enjoy complete solitude and coveted NM sunset's from this fully equipped 3 Br + 2 Bth farmhouse with office. Just 10 minutes from the Historic Old Mesilla Plaza and Downtown LC, this newly built oasis with mountain views is both convenient and private. Directly behind the home lies Outfall Channel bike path, spanning 4.4 miles through urban and agricultural settings. Pet friendly yard, fit with patio, hot tub, firepit, and cornhole allows every opportunity to enjoy our remarkable SW skies.

The Alamo on Ocotillo
Enjoy this secluded desert oasis at the Alamo on Ocotillo. This fabulous spacious home is nestled in a quiet neighborhood conveniently located less than 2 miles from the university. Relax in the seasonal pool, enjoy time with family and friends in the various cozy outdoor spaces and take in some shopping in old Mesilla. Numerous travelers love to explore the Dripping Springs trails with an invigorating day hike. You'll find this home to be the peaceful "get away" you are looking for.

Cozy condo in Mesilla, gated community.
UPDATED APPLIANCES AC, HEATER. RECLINER SOFA Located in Old Mesilla, my cozy, quiet condo is on the second floor nicely decorated Santa Fe style, 2 bedroom, 2 baths. The condo is within walking distance to the Plaza, and restaurants. Kids and dogs up to 20 lb are welcome. Come to enjoy the quietest condo in the complex. Our goal is to make feel our guests in a "Home sweet home". We warranty fresh linen and towels, squeaky and clean sanitized toilettes. and bathrooms.

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Pet Friendly Luxury Retreat W/ Heated Pool & Spa
Freshly remodeled luxury home in the heart of Las Cruces, located just 5 minutes from down town in a safe quite neighborhood! Enjoy local restaurants and bars just minutes away! Wood floors throughout the home, with granite countertops and brand new appliances!Massive open floor plan in the kitchen area with an 85 inch TV and surround sound system! Heated Pool and Spa for year round use! Pet friendly fully enclosed back yard! You will never want to leave this Luxury Oasis!

Cozy Casita w/private patio near Old Mesilla
This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

NEW! 5 Bedroom Mesilla St Charmer- Remodeled!
This newly updated 5 bedroom, 2 bathroom house is located in a quiet neighborhood close to Mesilla, Downtown Las Cruces, NMSU, dining and much more. This little gem is the perfect location for your next Las Cruces stay. This home has 5 bedrooms, all with TVs. Living room has large TV as well. One large bedroom also has a futon to accommodate two more people. The kitchen has seating for 14 total including the island. Enough glass and serve ware for 12.

4 Bedroom Contemporary Model home
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

Casita de Colibrí | Hot Tub • Walk to Old Mesilla
Escape to Casa de Colibrí, a private Southwest-inspired casita just a short walk from the historic Old Mesilla Plaza, restaurants, cafés, shops, and local attractions. Relax in your private hot tub, unwind on the peaceful patio, and enjoy a comfortable stay with fast Wi-Fi, a cozy bed, and thoughtful amenities. Whether you’re here to explore Las Cruces or simply relax, Casa de Colibrí is the perfect home away from home.

2 bed in Historic Mesilla, yard, pet friendly
Welcome to Casa de Sapo Verde! Nestled just outside the center of the historic Mesilla Plaza and on the edge of the area’s farmland, this cozy casita is the best of both worlds. Stay in this authentic Adobe home with vigas, coved ceilings, and brick floors and experience all Mesilla has to offer. Restaurants, galleries, and shops are all nearby, or you can stroll the ditch banks by neighboring farms.

Rustic Downtown Hideaway
This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.
Popular amenities for Mesilla pet-friendly home rentals
Pet-friendly house rentals

Mountain Views l White Sands NP l Luxury Getaway

Connie’s Cozy Abode

Shadow Mountain near NMSU

Executive Hills

Lus Solar Tranquila gated community/golf course

King Bed |Spacious house |Pets OK

New Modern/Cozy Spacious Home

3 Bedrooms Haciendas de Horacio in Mesilla.
Pet-friendly home rentals with a pool

Desert Peaks Casita

Year Round Heated Pool, Fast Wifi, Pet Friendly

[Pool open] Nature Retreat 12-min from Downtown

Sancho's Condo De Mesilla

Southwestern Hilltop Retreat

Private Oasis Near Old Mesilla with Pool/Spa

New Home with community pool and golf

Luxury Oasis Best Location • PingPong • CoffeeBar
Private, pet-friendly home rentals

The Stranded Time Traveler; a timeless experience!

Cul-de-sac Condo

Beautiful Mediterranean Home in Mesilla Park

Casitas @ Fort Fillmore (Unit 3)

Gary’s Full House sleeps 6

Casita; Peaceful, West of River, Dog Friendly

Casita de Sueños -Seen On Visit Las Cruces YouTube

Mountain-View Home, Coffee Lover’s Bar, Fast Wifi
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | €94 | €92 | €94 | €106 | €103 | €95 | €84 | €85 | €77 | €85 | €94 | €94 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Destinations to explore
- Tucson Vacation rentals
- Albuquerque Vacation rentals
- El Paso Vacation rentals
- Ciudad Juárez Vacation rentals
- Chihuahua Vacation rentals
- Santa Fe Vacation rentals
- Ruidoso Vacation rentals
- Las Cruces Vacation rentals
- Gilbert Vacation rentals
- Nogales Vacation rentals
- Midland Vacation rentals
- Carlsbad Vacation rentals
- White Sands National Park
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- El Paso Chihuahuas
- San Jacinto Plaza
- Sunland Park Racetrack & Casino
- Farmers And Crafts Market of Las Cruces
- New Mexico Farm & Ranch Heritage Museum
- Dripping Springs Natural Area
- Southwest University Park
- Western Playland
- Plaza Theatre
- Memorial Park
- Mesilla Plaza
- Casa de Juan Gabriel
- Museo de la Revolución en la Frontera
- Chamizal National Memorial
- El Paso Museum of Art
- La Rodadora Espacio Interactivo
- El Paso Zoo





