Pet-friendly vacation rentals in Mesilla

Find and book unique pet-friendly homes on Airbnb

Quick stats about vacation rentals that are pet-friendly in Mesilla

  • Total vacation rentals

    Explore 30 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at €35 per night before taxes and fees

  • Verified guest reviews

    Over 2,920 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated pet-friendly home rentals in Mesilla

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
An inviting outdoor space features a sparkling heated pool surrounded by comfortable lounge chairs. Palm trees and landscaping enhance the private backyard atmosphere. The home is visible in the background, illuminated as twilight sets in, creating a tranquil setting for relaxation.
Home in Las Cruces
4.89 out of 5 average rating, 140 reviews

Sunsets In Sonoma W/Heated Pool! Pet Friendly

Experience luxury living in one of Las Cruces’s most upscale and desirable neighborhoods. Seconds away from Sonoma Ranch golf course and Country Club. You’ll enjoy magical sunsets while swimming in our year round heated pool. Large, completely enclosed back yard for privacy and pets. Complete with games and ping pong table.A stand alone Casita is available for an additional fee, including separate climate control TV and a queen sized sofa sleeper (there is no bathroom in casita).Vacation awaits!

Top guest favorite
A welcoming porch features two light blue chairs positioned beside a rustic table under a wooden beam ceiling. A ceiling fan hangs above, and a colorful door adds a touch of character. A dried chili pepper wreath decorates the entryway, enhancing the outdoor oasis.
Guesthouse in Mesilla
5.0 out of 5 average rating, 251 reviews

Ocotillo Casita in Historic Mesilla

Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Top guest favorite
A hot tub is situated under a wooden pergola, with warm water gently bubbling. The backdrop features an open sky transitioning to twilight, while cozy seating is arranged nearby on a grassy area, offering a tranquil outdoor space.
Home in Las Cruces
4.99 out of 5 average rating, 159 reviews

Modern Farmhouse Near Bike Path

Enjoy complete solitude and coveted NM sunset's from this fully equipped 3 Br + 2 Bth farmhouse with office. Just 10 minutes from the Historic Old Mesilla Plaza and Downtown LC, this newly built oasis with mountain views is both convenient and private. Directly behind the home lies Outfall Channel bike path, spanning 4.4 miles through urban and agricultural settings. Pet friendly yard, fit with patio, hot tub, firepit, and cornhole allows every opportunity to enjoy our remarkable SW skies.

Guest favorite
A warm-colored exterior of a one-story home is highlighted by evening sunlight. Lush green trees and desert plants are arranged around the entrance, while a gravel driveway leads up to the front door. A subtle rainbow can be seen in the sky, adding a serene touch.
Home in Las Cruces
4.84 out of 5 average rating, 193 reviews

The Alamo on Ocotillo

Enjoy this secluded desert oasis at the Alamo on Ocotillo. This fabulous spacious home is nestled in a quiet neighborhood conveniently located less than 2 miles from the university. Relax in the seasonal pool, enjoy time with family and friends in the various cozy outdoor spaces and take in some shopping in old Mesilla. Numerous travelers love to explore the Dripping Springs trails with an invigorating day hike. You'll find this home to be the peaceful "get away" you are looking for.

Top guest favorite
Condo in Las Cruces
4.92 out of 5 average rating, 102 reviews

Cozy condo in Mesilla, gated community.

UPDATED APPLIANCES AC, HEATER. RECLINER SOFA Located in Old Mesilla, my cozy, quiet condo is on the second floor nicely decorated Santa Fe style, 2 bedroom, 2 baths. The condo is within walking distance to the Plaza, and restaurants. Kids and dogs up to 20 lb are welcome. Come to enjoy the quietest condo in the complex. Our goal is to make feel our guests in a "Home sweet home". We warranty fresh linen and towels, squeaky and clean sanitized toilettes. and bathrooms.

Top guest favorite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 410 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favorite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.96 out of 5 average rating, 395 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Guest favorite
The kitchen features modern appliances, including an oven, microwave, and two-basin sink. Light-colored cabinets are complemented by a granite countertop. Essential utensils are organized in a holder, with a coffee maker and spice rack visible.
Home in Las Cruces
4.95 out of 5 average rating, 124 reviews

NEW! 5 Bedroom Mesilla St Charmer- Remodeled!

This newly updated 5 bedroom, 2 bathroom house is located in a quiet neighborhood close to Mesilla, Downtown Las Cruces, NMSU, dining and much more. This little gem is the perfect location for your next Las Cruces stay. This home has 5 bedrooms, all with TVs. Living room has large TV as well. One large bedroom also has a futon to accommodate two more people. The kitchen has seating for 14 total including the island. Enough glass and serve ware for 12.

Superhost
A spacious living area features a large gray sectional sofa with decorative cushions. A wooden coffee table sits in front, while light fixtures illuminate the room. The kitchen area is visible in the background, showcasing white cabinets and a decorative tile backsplash.
Home in Las Cruces
4.87 out of 5 average rating, 313 reviews

4 Bedroom Contemporary Model home

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Mesilla
4.99 out of 5 average rating, 273 reviews

Casita de Colibrí | Hot Tub • Walk to Old Mesilla

Escape to Casa de Colibrí, a private Southwest-inspired casita just a short walk from the historic Old Mesilla Plaza, restaurants, cafés, shops, and local attractions. Relax in your private hot tub, unwind on the peaceful patio, and enjoy a comfortable stay with fast Wi-Fi, a cozy bed, and thoughtful amenities. Whether you’re here to explore Las Cruces or simply relax, Casa de Colibrí is the perfect home away from home.

Guest favorite
A spacious outdoor area is captured, featuring a vibrant clay chiminea surrounded by gravel. Nearby, blue and terracotta pots add color. Lush greenery from trees and shrubs is visible, while a stone wall and gated entrance provide a sense of privacy and enclosure.
Home in Mesilla
4.89 out of 5 average rating, 152 reviews

2 bed in Historic Mesilla, yard, pet friendly

Welcome to Casa de Sapo Verde! Nestled just outside the center of the historic Mesilla Plaza and on the edge of the area’s farmland, this cozy casita is the best of both worlds. Stay in this authentic Adobe home with vigas, coved ceilings, and brick floors and experience all Mesilla has to offer. Restaurants, galleries, and shops are all nearby, or you can stroll the ditch banks by neighboring farms.

Top guest favorite
Guesthouse in Las Cruces
4.94 out of 5 average rating, 241 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Popular amenities for Mesilla pet-friendly home rentals

When is the best time to visit Mesilla?

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