
House vacation rentals in James Island
Find and book unique houses on Airbnb
Top-rated house rentals in James Island
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island house rentals
House rentals with a pool

LONGWAY~family home with pool, hot tub & game room

2500SF Downtown 1849 home w/ pool!

Private Entrance Suite w/ pool, 5 min from beach

Hammock Haus -cozy firetable- 10 min to downtown

Beautiful 2BD/2BA Seabrook Island Villa

Blue Bungalow- 22 min to beach with huge yard

Park Circle Private Pool, Putting Green, & 3 Kings

Family Retreat | Pool | Game Room | Fenced Yard
Weekly house rentals

The Perfect Charleston Oasis

Pelicans Perch! Beach chairs included

Waterfront Home 5 minutes From Downtown Charleston

Charming 2 Bed/2Bath Newly Renovated-Location!

Santorini Cottage

James Island Creek Retreat | On the Water |

Renovated - 3 Bed Home - 10 Minutes to Downtown!

Charming 2 Bedroom Charleston Cottage!
Private house rentals

Teal Door Inn

Charleston Waterfront Retreat w/ Deep Water Dock

Life's Good! mins to Folly and 15 min to downtown

Centrally Located Home | 10 min to DT & Folly

Coastal Retreat Near Folly Beach

James Island Retreat

Casa Zoë | Historic Garden Carriage House CHS

Pet Friendly ~ Fenced Yard ~ Fully Loaded
Destinations to explore
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- Kid-friendly rentals James Island
- Rentals with a hot tub James Island
- Beachfront rentals James Island
- Guesthouse rentals James Island
- Rentals with a kayak James Island
- Townhouse rentals James Island
- Pet-friendly rentals James Island
- Family-friendly rentals James Island
- Waterfront rentals James Island
- Rentals with a washer and dryer James Island
- Apartment rentals James Island
- Rentals with pools James Island
- Rentals with a fireplace James Island
- Rentals with beach access James Island
- Villa rentals James Island
- Rentals with breakfast James Island
- Rentals with outdoor seating James Island
- Condo rentals James Island
- Rentals with an EV charger James Island
- Bed and breakfasts James Island
- Rentals with a patio James Island
- Private suite rentals James Island
- Rentals with lake access James Island
- Rentals with a fire pit James Island
- Fitness-friendly rentals James Island
- House rentals Charleston County
- House rentals South Carolina
- House rentals United States
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- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
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- Private Island Rentals United States
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- Cabin Rentals Australia
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- Big House Rentals United States
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- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Middleton Place
- Hampton Park
- The Golf Club at Wescott Plantation
- James Island County Park
- The Charleston Museum
- Harbor Island Beach
- Yeamans Hall Club
- Shem Creek Park
- Angel Oak Tree
- Waterfront Park
- Bull Point Beach
- Secession Golf Club
- Seabrook Beach
- Gibbes Museum of Art
- White Point Garden
- Morris Island Lighthouse
- Isle of Palms Beach
- Hunting Island Beach
- The Beach Club
- Seabrook Island Beach
- Driftwood Beach
- Cougar Point Golf Course
- Things to do James Island
- Sports activities James Island
- Nature and outdoors James Island
- Tours James Island
- Things to do Charleston County
- Art and culture Charleston County
- Food and drink Charleston County
- Nature and outdoors Charleston County
- Tours Charleston County
- Sports activities Charleston County
- Sightseeing Charleston County
- Things to do South Carolina
- Nature and outdoors South Carolina
- Entertainment South Carolina
- Art and culture South Carolina
- Sports activities South Carolina
- Tours South Carolina
- Sightseeing South Carolina
- Food and drink South Carolina
- Things to do United States
- Sightseeing United States
- Entertainment United States
- Sports activities United States
- Nature and outdoors United States
- Wellness United States
- Art and culture United States
- Tours United States
- Food and drink United States