Villa vacation rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Villa rentals with a pool
Villa in Seabrook Island
5.0 out of 5 average rating, 11 reviewsClose to beach, pools,golf & tennis+Amenity Card
Nov 22 – 29
Villa in Saint Helena Island
4.99 out of 5 average rating, 78 reviewsSandy Toes Condos
Oct 31 – Nov 7
Villa in Seabrook Island
4.83 out of 5 average rating, 59 reviewsPrivate island villa with luxury resort amenities!
Oct 15 – 22
Villa in Seabrook Island
4.9 out of 5 average rating, 31 reviewsUpscale Villa, Amenity Included! Dog Friendly
Nov 8 – 15
Villa in Seabrook Island
4.97 out of 5 average rating, 59 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Jan 3 – 10
Villa in Seabrook Island
4.85 out of 5 average rating, 33 reviewsSeabrook Golf View Villa: Pickleball, Pool & Bike
Oct 9 – 16
Villa in Seabrook Island
4.92 out of 5 average rating, 52 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Feb 26 – Mar 5
Villa in Folly Beach
4.84 out of 5 average rating, 61 reviews83 Waters Edge - Comfy Cool - Pool
Aug 18 – 25
Private villa rentals
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Oct 23 – 30
Villa in Kiawah Island
4.97 out of 5 average rating, 86 reviewsLagoon view villa with office, easy walk to beach!
Dec 9 – 16
Villa in Edisto Island
4.73 out of 5 average rating, 52 reviewsLoft-e-Lagoon *No Cleaning Fee*
Nov 12 – 19
Villa in Kiawah Island
4.93 out of 5 average rating, 96 reviewsClean & Comfortable! Steps to the beach!
May 15 – 22
Villa in Edisto Island
4.97 out of 5 average rating, 36 reviewsRelax in a Happy Place
Mar 3 – 10
Villa in Seabrook Island
4.86 out of 5 average rating, 51 reviews711 Spinnaker centrally located to EVERYTHING!
Jan 21 – 28
Villa in Saint Helena Island
4.92 out of 5 average rating, 38 reviewsBeachfront Oasis: Condo w/ Deck + Pool Access
Oct 20 – 27
Villa in Mount Pleasant
4.94 out of 5 average rating, 16 reviewsCoastal 3BR in Old Village with patio & yard
Jul 12 – 19
Luxury villa rentals
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Oct 5 – 12
Villa in Seabrook Island
4.9 out of 5 average rating, 10 reviewsLuxury Seabrook Isl Beach Condo
Aug 11 – 18
Villa in Kiawah Island
Oceanfront! Renovated Mariners Watch
Oct 10 – 17
Villa in Sullivan's Island
4.57 out of 5 average rating, 21 reviewsHaven by AvantStay | Luxury Beachfront Retreat
Nov 17 – 24
Villa in Kiawah Island
5.0 out of 5 average rating, 15 reviewsOceanfront Windswept Villa
Aug 23 – 30
Villa in Isle of Palms
5.0 out of 5 average rating, 4 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Dec 25 – Jan 1
Villa in Kiawah Island
5.0 out of 5 average rating, 18 reviewsLuxury Penthouse 2 BR 3 Bath Villa with Ocean View
Dec 27 – Jan 3
Villa in Kiawah Island
4.94 out of 5 average rating, 52 reviewsOpen floor plan 2 Bedroom Turtle Cove Villa
Jul 5 – 12
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
€ 159 before taxes and fees
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- Beach condo rentals Isle of Palms
- Family-friendly rentals Isle of Palms
- Rentals with pools Isle of Palms
- Rentals with beach access Isle of Palms
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- Rentals with a patio Isle of Palms
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