Skip to content
Sign up
Log in
Vacation rental beach houses in Isle of Palms

Vacation rental beach houses in Isle of Palms

Book beachfront vacation rental houses, apartments, and more on Airbnb

Top-rated houses in Isle of Palms

Guests agree: these stays are highly rated for location, cleanliness, and more.

Private Lowcountry Get-A-Way
SUPERHOSTPrivate room · 2 guests · 1 bed · 1.5 baths
Private Lowcountry Get-A-Way

The best of both worlds... a peaceful respite just minutes from historic downtown Charleston. Walk to Sunrise Park. Canoe the tidal creek. Visit Folly Beach (only 12 minutes!). Bicycle oak and azalea lined avenues. Relax on the back porch. Get-a-Way!

Historical Southern Charmer w/ Off Street Parking
SUPERHOSTEntire house · 4 guests · 1 bed · 1 bath
Historical Southern Charmer w/ Off Street Parking

Two blocks off King Street, Cayo Cañón is located in Charleston’s charming historic Cannonborough-Elliottborough (C-E) neighborhood. A traditional (1835) Charleston home, our listing features the home’s entire first floor (1100 sqft), one king bed, one sofa bed, a breakfast nook, deck, gated off street parking, and plenty of outdoor space. When staying at Cayo Cañón, you’ll find yourself steps away from the Holy City’s highest rated restaurants, bars, historical sites, parks, and shopping.

Private Lowcountry Cottage
SUPERHOSTEntire house · 4 guests · 2 beds · 1 bath
Private Lowcountry Cottage

The best of both worlds... a peaceful respite just eight minutes from historic Charleston. Walk to Sunrise Park. Visit Folly Beach. Bicycle oak and azalea lined avenues. Relax on the front porch. Come for a night or stay for a week... the cottage is yours!

Vacation rentals for every style

Get the amount of space that is right for you

  • Homes
  • Hotels
  • Unique stays

Popular house amenities in Isle of Palms

  • Pool
  • Pets allowed
  • Air conditioning
  • Wifi
  • Kitchen

Apartments in Isle of Palms

Old World Meets New Lux in an Historic Apartment
PLUSEntire apartment
Old World Meets New Lux in an Historic Apartment
Price:€214 / night
comfy cottage nestled in the old village
SUPERHOSTEntire apartment
comfy cottage nestled in the old village
Price:€89 / night
DOWNTOWN-14' CEILINGS 2BR, 2BA, AND OLD CISTERN
SUPERHOSTEntire apartment
DOWNTOWN-14' CEILINGS 2BR, 2BA, AND OLD CISTERN
Price:€75 / night
Modern cozy space on the outskirts of Park Circle
SUPERHOSTEntire apartment
Modern cozy space on the outskirts of Park Circle
Price:€73 / night
Cannon St. Suite D
SUPERHOSTEntire apartment
Cannon St. Suite D
Price:€102 / night
Steps from the beach - 1 bedroom - Folly Beach
SUPERHOSTEntire apartment
Steps from the beach - 1 bedroom - Folly Beach
Price:€115 / night
A Blend of Historic Charm and Modern Luxury
PLUSEntire apartment
A Blend of Historic Charm and Modern Luxury
Price:€146 / night
Relax with a Game of Darts at an Airy, Bohemian Loft
PLUSEntire apartment
Relax with a Game of Darts at an Airy, Bohemian Loft
Price:€142 / night
Taste Charleston -Lite-Cozy Studio
SUPERHOSTEntire apartment
Taste Charleston -Lite-Cozy Studio
Price:€91 / night
Charleston (downtown) next to Hampton Park
SUPERHOSTEntire apartment
Charleston (downtown) next to Hampton Park
Price:€86 / night
Low Country Casa!
SUPERHOSTEntire apartment
Low Country Casa!
Price:€33 / night
Southern Shangri-La in Cannonborough-Elliotborough
PLUSEntire apartment
Southern Shangri-La in Cannonborough-Elliotborough
Price:€171 / night
Show all

Pet-friendly houses

PetsOK-SmRm-PrivBa-PrivEntry-Kayaks-Fridge-Marsh
SUPERHOSTPrivate room
PetsOK-SmRm-PrivBa-PrivEntry-Kayaks-Fridge-Marsh
Price:€60 / night
Beach Life/City Life
SUPERHOSTEntire house
Beach Life/City Life
Price:€99 / night
Entire 5 Rooms W/Media Rm by Surf &City share/w us
Private room
Entire 5 Rooms W/Media Rm by Surf &City share/w us
Price:€72 / night
HIP DOWNTOWN 2BR BUNGALOW + PARKING
SUPERHOSTEntire house
HIP DOWNTOWN 2BR BUNGALOW + PARKING
Price:€118 / night
Beautiful Historic Home. One Block Off King Street.
PLUSEntire house
Beautiful Historic Home. One Block Off King Street.
Price:€491 / night
Seewee Cottage ( 1 blk from beach)
SUPERHOSTEntire house
Seewee Cottage ( 1 blk from beach)
Price:€173 / night
3BD/3BA HOUSE!  Walk to King St, 4 Queen Beds!
SUPERHOSTEntire house
3BD/3BA HOUSE! Walk to King St, 4 Queen Beds!
Price:€322 / night
PetsOK-LgRm-PrivEntry-PrivBath-Fridge-Kayaks-Marsh
SUPERHOSTPrivate room
PetsOK-LgRm-PrivEntry-PrivBath-Fridge-Kayaks-Marsh
Price:€77 / night
Salt Marsh Ranch
SUPERHOSTPrivate room
Salt Marsh Ranch
Price:€54 / night
Rosé Getaway: Live Like A Local in this Luxury 3BD Home
SUPERHOSTEntire house
Rosé Getaway: Live Like A Local in this Luxury 3BD Home
Price:€247 / night
Comfy & Cozy right Downtown. Permit OP2  019-00450
SUPERHOSTEntire house
Comfy & Cozy right Downtown. Permit OP2 019-00450
Price:€123 / night
Private getaway between downtown & Folly Beach
SUPERHOSTEntire house
Private getaway between downtown & Folly Beach
Price:€130 / night
Show all

Houses with pools

Coastal Family Getaway, Heated Pool
SUPERHOSTEntire house
Coastal Family Getaway, Heated Pool
Price:€326 / night
AMAZING Views. Safe/Clean Haven. Pool. On Marsh!
SUPERHOSTPrivate room
AMAZING Views. Safe/Clean Haven. Pool. On Marsh!
Price:€79 / night
4 BD/4BA- 1 MIN WALK TO BEACH, TENNIS, GOLF *NEW*
SUPERHOSTEntire house
4 BD/4BA- 1 MIN WALK TO BEACH, TENNIS, GOLF *NEW*
Price:€334 / night
Country In The City Room 2
SUPERHOSTPrivate room
Country In The City Room 2
Price:€60 / night
2500SF Downtown 1849 home w/ pool and roof deck!
SUPERHOSTEntire house
2500SF Downtown 1849 home w/ pool and roof deck!
Price:€520 / night
Close to Beach, Charming,Diamond Drive Mt Pleasant
SUPERHOSTEntire house
Close to Beach, Charming,Diamond Drive Mt Pleasant
Price:€171 / night
Spacious Custom Home with Pool 3 miles from Folly
SUPERHOSTEntire house
Spacious Custom Home with Pool 3 miles from Folly
Price:€524 / night
Riverland Ter/CHS, SC/HTD Pool/Spa-STR#4-19-210485
SUPERHOSTEntire house
Riverland Ter/CHS, SC/HTD Pool/Spa-STR#4-19-210485
Price:€221 / night
CASA INTRACOASTAL on Isle of Palms
SUPERHOSTEntire house
CASA INTRACOASTAL on Isle of Palms
Price:€800 / night
Charleston Southern Hospitality
SUPERHOSTPrivate room
Charleston Southern Hospitality
Price:€56 / night
Fred Street's Pool Oasis
SUPERHOSTEntire house
Fred Street's Pool Oasis
Price:€221 / night
Country In The City
SUPERHOSTPrivate room
Country In The City
Price:€60 / night
Show all