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Family-friendly vacation rentals in Cayce

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Cayce

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
A dining area is presented with a round table surrounded by four wooden chairs. A delicate chandelier provides overhead lighting, while a window with sheer curtains allows natural light to enter. A soft-colored wall enhances the serene space, complemented by a wall art piece.
Home in West Columbia
4.92 out of 5 average rating, 279 reviews

Lucy’s Place

This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Top guest favorite
The studio features a spacious bed with white bedding, complemented by a green accent pillow. A cozy seating area includes two armchairs and a small coffee table. The kitchenette is visible in the background, enhancing the open layout of the space.
Guest suite in Columbia
4.99 out of 5 average rating, 1,069 reviews

Private Studio Apartment

Crisp and cozy, modern studio apartment with private entrance, and access to park-like backyard, located right in the center of the Columbia, Irmo and Ballentine areas of SC. Quiet and tidy neighborhood, with free off-street parking for up to two vehicles. Just minutes from Lake Murray, Saluda Shoals Park and River, shopping and restaurants, approximatly 15-20 minutes from down town Columbia, the Vista, U of SC & CIU campuses, Williams-Brice Stadium, and about 20-25 minutes from Fort Jackson.

Top guest favorite
A well-arranged bedroom features a spacious bed dressed in white linens and a grey throw blanket. Two reading lamps are positioned on either side of the headboard. Carpeting covers the floor, and natural light filters through a window dressed with white curtains.
Apartment in Columbia
4.96 out of 5 average rating, 101 reviews

Heathwood 2Br/1Bath Cozy Home

Close to everything when you stay at this centrally located duplex. Close to the grocery store and restaurants. Five Points (1.5 miles), the Vista (2.5 miles), Township Auditorium (2 miles), USC (2 miles), and Ft Jackson (3 miles). This freshly renovated unit includes 2 bedrooms, 1 bath, fully equipped kitchen (including a k-cup coffee maker), washer and dryer. Both bedrooms have memory foam beds (1 King & 1 Queen). Keyless entry. Off street parking for 2 cars. COC Permit STRN-001336-10-2026

Guest favorite
The exterior of a well-maintained mobile home showcases a welcoming entrance with wooden steps leading up to the door. Symmetrical windows are framed by shutters, and decorative landscaping features manicured shrubs along the foundation, contributing to a tidy and inviting appearance.
Tiny home in West Columbia
4.95 out of 5 average rating, 239 reviews

Supersized Tiny House in Rest Haven MH Park

Enjoy the convenience of this tiny home nestled in a neighborhood with shops, restaurants, and attractions nearby. Nearby: Local hospital: Just 3 blocks away Riverbanks Zoo & Gardens: A quick 4-mile drive Fort Jackson: 11 miles Congaree National Park: 22 miles University of South Carolina: 6.5 miles Interstate 26 (3 blocks) Exit 110 Located within an adult mobile home community with onsite management. Ensuring a peaceful and secure environment, surrounded by friendly older residents.

Guest favorite
A charming outdoor space is surrounded by lush greenery, featuring a table with chairs and a wooden bench. The cottage is visible with vibrant yellow doors, while the nearby building provides additional context. Colorful flowers are arranged in pots throughout the garden.
Guesthouse in Elmwood Park
4.89 out of 5 average rating, 968 reviews

Lizzi & Scott’sTiny Guest House secluded USC-Vista

Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in. STRO-000579-03-2024

Top guest favorite
The exterior of a detached studio apartment is shown, featuring a light-colored façade and a charming blue door. Two large windows provide natural light, while a shaded carport is visible on the left. Lush greenery surrounds the entrance, contributing to a serene environment.
Guesthouse in Cayce
4.89 out of 5 average rating, 152 reviews

The Avenues Bungalow

This space is great for a solo traveler or a couple! Great location, quiet neighborhood, close to everything. Mile and a half from USC campus (Carolina Baseball stadium, Colonial Life Arena and State house). Five miles from airport. Three miles from Williams-Brice Stadium. Three Miles from 5 points. Music venues, restaurants and riverwalk around the corner! Please note: This is a studio apartment in the back of a single family home. Private driveway, entrance and space.

Top guest favorite
A cozy dining area features a round wooden table surrounded by a mix of modern and rustic seating. Natural light is welcomed through nearby windows, and warm lighting is provided by hanging pendant fixtures. A decorative storage unit displays various items, adding character to the space.
Home in Cayce
4.96 out of 5 average rating, 157 reviews

High-styled Historic - (UofSC)

Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

Top guest favorite
Guest suite in Columbia
4.95 out of 5 average rating, 238 reviews

Farmhouse Chic

Welcome to your cozy home-away-from-home in Columbia, South Carolina — where southern charm meets modern comfort. Whether you’re in town for a loved one’s graduation at Fort Jackson, exploring the natural wonders of Congaree National Park, or soaking in the culture and cuisine of Downtown Columbia, you’ve found the perfect base. Book now and experience the best of Columbia, where city life, military pride, and natural beauty come together in perfect balance.

Guest favorite
A bright living area features a soft color palette with a cozy rug underfoot. A pair of comfortable sofas are positioned around a wooden coffee table. Light from windows illuminates the space, enhancing the welcoming atmosphere, and an open archway leads to the dining area.
Home in Cayce
4.96 out of 5 average rating, 101 reviews

In Columbia Metro! Easy drive to Fort Jackson/USC

Metro Columbia. 1.5 miles to USC. 9 miles to Fort Jackson! Entire single family home. Two bedrooms. One has a KING bed and the other has a QUEEN bed. One bath. Additional rollaway bed in an enclosed sunroom. Includes linens, sofa, loveseat, refrigerator, dishwasher, garbage disposal, wash machine, dryer, outdoor covered patio with rocking chairs and dining table overlooking the huge fenced, private backyard. Bright, comfortable, quiet. Plenty of parking.

Guest favorite
A charming brick exterior features a welcoming entrance with steps leading to a covered porch adorned with plants. Large windows allow natural light to brighten the interior. Surrounding greenery provides a tranquil setting in a peaceful residential neighborhood.
Apartment in Earlewood
4.93 out of 5 average rating, 304 reviews

The Toad Abode Studio

Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.

Guest favorite
A spacious sleeping area features a large bed adorned with a floral patterned coverlet. Two nightstands with lamps flank the bed, and windows are positioned on either side, allowing soft natural light. A bathroom entrance can be seen in the background, framed by green walls.
Guest suite in Columbia
4.94 out of 5 average rating, 151 reviews

Cozy Rosewood Bungalow

Keep it simple at this peaceful and centrally-located place. Rosewood is convenient to so much of Columbia - and our place is in a super-walkable location! Publix is about 2 blocks away, and there are quite a few restaurants (and a brewery) within walking distance. We're also quite convenient to Fort Jackson and MUSC. The street is quiet, and the entrance and parking for the bungalow are behind a 6-foot fence, so it offers great security too.

Guest favorite
A small guesthouse is depicted with a light-colored exterior and a single door. Lush greenery surrounds the entrance, including various potted plants. A simple pathway leads to the door, creating a welcoming approach.
Guesthouse in Shandon
4.78 out of 5 average rating, 401 reviews

Writer's haven in private guesthouse.

Cozy guesthouse makes an ideal writer's retreat! Located in an attractive, quiet neighborhood close to dining and shopping. On-street parking on non-busy side street. Hosts will work with you on creating fun rewards for writing goals. Space has a microwave, refrigerator, coffee maker, and electric kettle, and hosts will provide coffee, tea, wine, bottled water, and snacks, as well as continental breakfast.

Popular amenities for Cayce family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Cayce

  • Total vacation rentals

    Explore 240 vacation rentals in Cayce

  • Nightly prices starting at

    Cayce vacation rentals start at € 35 per night before taxes and fees

  • Verified guest reviews

    Over 14,690 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 100 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    150 properties have a dedicated workspace

  • Wi-Fi availability

    240 of Cayce vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Cayce rentals

  • 4.8 Average rating

    Cayce stays are highly rated by guests—averaging 4.8 out of 5!