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House vacation rentals in San Luis Obispo

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Top-rated house rentals in San Luis Obispo

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A quaint blue cottage is surrounded by vibrant landscaping featuring various colorful plants and natural stones. Wispy trees provide shade, while a fence adds a rustic touch to the serene setting. This exterior view highlights the cottage's inviting entrance and well-maintained garden.
Home in Los Osos
4.95 out of 5 average rating, 366 reviews

Baywood Park Garden Cottage

Cosy and cute, private one bedroom tiny cottage in Baywood Park. Just minutes to Morro Bay or explore the ocean bluffs, bay and hiking trails in Montana de Oro State Park. The tiny house cottage resides in a sunny semi-rural residential neighborhood, just minutes to the bay and Elfin Forest. Comfy queen size bed in the separate one bedroom, large shower, full kitchen and dining area, private deck to watch the sunrise or sunset. Perfect for a short stay or to finally finish that novel :)

Guest favorite
An open kitchenette features bright natural light from multiple windows, creating a welcoming space. A round wooden dining table with white chairs is accompanied by a leafy green plant. Cabinets and a stainless-steel dishwasher are visible, all arranged against a neutral-toned backdrop.
Home in San Luis Obispo
4.97 out of 5 average rating, 278 reviews

The Quailhouse on Ranch near Avila Beach

The Quailhouse is located on a gated, rural working Ranch in Avila Valley - San Luis Obispo. Avila Beach and downtown San Luis Obispo are just a 7 minute drive away. You are centrally located for enjoying the Central Coast, while being privately tucked away in nature from the hustle and bustle. Nearby are hiking/biking trails, beaches, wineries and restaurants. Enjoy a distinctive experience that includes locally sourced, environmentally friendly amenities while relaxing in a serene setting.

Top guest favorite
A fresh bedroom features exposed wooden beams and soft lighting. A spacious bed is centered against a wooden headboard, and light filters through a window adorned with subtle blinds. Simple artwork complements the light-colored walls, contributing to a calming environment.
Home in Los Osos
4.99 out of 5 average rating, 165 reviews

Back Bay Getaway - Dog Friendly - Home in Los Osos

Our peaceful home is located a short walk from the back bay of Los Osos. Its new design makes for a restful getaway with its luxurious bedroom, hot tub, and soothing bath. Our home is close to many local favorite hiking, biking, kayaking, surfing, and paddle boarding locations such as Montana de Oro and Morro Bay. The outdoor patio is the perfect setting for a family bbq with a lawn for your pets to play. A short distance away is delicious cuisine, coffee shops, golfing, and local art studios.

Top guest favorite
A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.
Home in San Luis Obispo
4.99 out of 5 average rating, 120 reviews

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Top guest favorite
A cozy seating area is presented, featuring two comfortable chairs on either side of a low table. A vase of sunflowers rests on the table, bringing a touch of warmth. The fireplace sits centrally against a light-colored wall, with windows allowing natural light to fill the space.
Home in Downtown SLO
4.91 out of 5 average rating, 317 reviews

Charming Bungalow In SLO MoJo District

COVid MEASUREMENTS IN PLACE: Additional days between guest stays before and after have been instituted to thoroughly clean and disinfect. This charming bungalow is within easy walking distance to Historic Mission and downtown, Cal Poly, restaurants and dining, art and culture, shopping, parks, and easy driving distance (15-30 min.) to four spectacular nearby beaches, wine tasting, hiking trails, biking, natural environments and great views. Reserved guest parking for one car in driveway.

Top guest favorite
A backyard patio features a circular fire pit surrounded by comfortable seating. String lights hang overhead, providing a warm glow. Greenery lines the perimeter, and the space is paved with stone tiles, creating an inviting area for relaxation and socializing.
Home in Downtown SLO
5 out of 5 average rating, 183 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Sit back next to the fire pit in the backyard, it's just a 7 min. walk to downtown & next to 5 restaurants including Sally Lou's coffee shop, Terrace Hill trail head & the train station. Experience SLO's charm like never before with this perfect location home. Book a stay!

Guest favorite
The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.
Home in Downtown SLO
4.84 out of 5 average rating, 163 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Guest favorite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.85 out of 5 average rating, 109 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 340 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Superhost
A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.
Home in Downtown SLO
4.76 out of 5 average rating, 170 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

Top guest favorite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in Downtown SLO
4.96 out of 5 average rating, 421 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 258 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Popular amenities for San Luis Obispo house rentals

Quick stats about house rentals in San Luis Obispo

  • Total vacation rentals

    Explore 180 vacation rentals in San Luis Obispo

  • Verified guest reviews

    Over 14,890 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    180 of San Luis Obispo vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

  • 4.9 Average rating

    San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!

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