
House vacation rentals in San Luis Obispo
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Top-rated house rentals in San Luis Obispo
Guests agree: these houses are highly rated for location, cleanliness, and more.

Baywood Park Garden Cottage
Cosy and cute, private one bedroom tiny cottage in Baywood Park. Just minutes to Morro Bay or explore the ocean bluffs, bay and hiking trails in Montana de Oro State Park. The tiny house cottage resides in a sunny semi-rural residential neighborhood, just minutes to the bay and Elfin Forest. Comfy queen size bed in the separate one bedroom, large shower, full kitchen and dining area, private deck to watch the sunrise or sunset. Perfect for a short stay or to finally finish that novel :)

The Quailhouse on Ranch near Avila Beach
The Quailhouse is located on a gated, rural working Ranch in Avila Valley - San Luis Obispo. Avila Beach and downtown San Luis Obispo are just a 7 minute drive away. You are centrally located for enjoying the Central Coast, while being privately tucked away in nature from the hustle and bustle. Nearby are hiking/biking trails, beaches, wineries and restaurants. Enjoy a distinctive experience that includes locally sourced, environmentally friendly amenities while relaxing in a serene setting.

Back Bay Getaway - Dog Friendly - Home in Los Osos
Our peaceful home is located a short walk from the back bay of Los Osos. Its new design makes for a restful getaway with its luxurious bedroom, hot tub, and soothing bath. Our home is close to many local favorite hiking, biking, kayaking, surfing, and paddle boarding locations such as Montana de Oro and Morro Bay. The outdoor patio is the perfect setting for a family bbq with a lawn for your pets to play. A short distance away is delicious cuisine, coffee shops, golfing, and local art studios.

Hilltop Horizon: Centrally Located+Panoramic Views
Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Charming Bungalow In SLO MoJo District
COVid MEASUREMENTS IN PLACE: Additional days between guest stays before and after have been instituted to thoroughly clean and disinfect. This charming bungalow is within easy walking distance to Historic Mission and downtown, Cal Poly, restaurants and dining, art and culture, shopping, parks, and easy driving distance (15-30 min.) to four spectacular nearby beaches, wine tasting, hiking trails, biking, natural environments and great views. Reserved guest parking for one car in driveway.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Sit back next to the fire pit in the backyard, it's just a 7 min. walk to downtown & next to 5 restaurants including Sally Lou's coffee shop, Terrace Hill trail head & the train station. Experience SLO's charm like never before with this perfect location home. Book a stay!

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Cozy Retreat Walking Distance to Downtown
This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views

Casa de Almendras - Amazing Views of Paso Robles.

Spacious 4bd Home w/ Pool, Spa + Pet Friendly!

30 acre Estate 5 min to Lake Nacimiento ~Wow Views

Luxury Mountain View Retreat Pool/jacuzzi

Poolside Paradise+Views+Wineries+Spa+Game Room

Getaway at the Oaks +Heated pool+hot tub

Historic House near Paso Robles, Pool & Hot Tub
Weekly house rentals

Family Home Close to Downtown

4.5 Acre Farmhouse in Wine Country w/Hot Tub

Entire Hobby Farm, Surrounded by Vineyards

Pelican Cove Vacation Rental at the Back Bay

The Farm House,Paso Robles| Firepit| Pet Friendly

Herter House Beach Retreat

Wine Country Bungalow

Downtown | Hottub | Sleeps 6
Private house rentals

Mid-century home in the heart of Arroyo Grande.

Farmhouse Bungalow close to Downtown Paso Robles

Ocean's Calling Cottage Sleeps five. 2 bed/2bath

Atascadero Hideaway

Peace and Tranquility - Morro Bay

The Beach House - On Cayucos Beach

Hillside view with hot tub too

Stylish SLO Home|Epic Sunset Views & Near Cal Poly
Quick stats about house rentals in San Luis Obispo
Total vacation rentals
Explore 180 vacation rentals in San Luis Obispo
Verified guest reviews
Over 14,890 verified reviews to help you choose
Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities
Pet-friendly vacation rentals
Find 60 rentals that welcome pets
Rentals with dedicated workspaces
90 properties have a dedicated workspace
Wi-Fi availability
180 of San Luis Obispo vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals
4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
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- Cayucos Beach
- Moonstone Beach
- Hearst San Simeon State Park
- Montaña de Oro State Park
- Natalie's Cove
- Cayucos State Beach
- Morro Strand State Beach
- B & E Vineyard & Winery
- Mission San Luis Obispo de Tolosa
- Dairy Creek Golf Course
- Morro Rock Beach
- Seal Beach
- Sand Dollars
- Point Sal State Beach
- Pismo State Beach
- Pirates Cove Beach
- Olde Port Beach
- Baywood Park Beach
- Morro Bay Golf Course
- Bianchi Winery
- Paradise Beach
- Spooner's Cove
- Allegretto Wines
- Bovino Vineyards
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