
Guesthouse vacation rentals in San Luis Obispo
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Luis Obispo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Luis Obispo guesthouse rentals
Family-friendly guest house rentals

Cozy Barn in Wine Country

Cedar Pines-Beautiful country getaway in the trees

Wine Country Casita

Wine Country Bungalow w/ Pool, Spa

Private SLO Lodge: Gym, Sauna, Views, Wineries!

Quaint cottage close to beach

The Lincoln Street Cottage | SANITIZED & SAFE!

Hidden oasis..escape to tranquility..
Guest house rentals with a patio

The Cozy Casita

Creekside guest house in SLO's historic district

The Shed

Unique Studio in Downtown SLO

Deerfield Cottage on Paso's wine road

McClellan Cottage - centrally located studio

Casita By the Sea: Secluded and Serene

Quiet country guest home
Guest house rentals with a washer and dryer

Renovated Private Hippy Beach Shack With Full Bath

Private top floor spacious 1 bedroom retreat

Bright, Airy and Beautifully Built!

Crooms Moonlight Ranch, Views and Amazing Sunsets!

Cottge On The Crt: Hike, Winery, Beaches 20 min

Maverick Bungalow

Central Coast Guest House - Private entrance

Petite Barn
Quick stats about guesthouse rentals in San Luis Obispo
Total rentals
30 properties
Nightly prices starting at
€ 68 before taxes and fees
Total number of reviews
5.1K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
30 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Destinations to explore
- Central California Vacation rentals
- Channel Islands of California Vacation rentals
- San Fernando Valley Vacation rentals
- Santa Monica Vacation rentals
- Los Angeles Vacation rentals
- San Francisco Peninsula Vacation rentals
- Stanton Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Francisco Vacation rentals
- Southern California Vacation rentals
- Gold Country Vacation rentals
- Northern California Vacation rentals
- Rentals with pools San Luis Obispo
- Family-friendly rentals San Luis Obispo
- Rentals with a fireplace San Luis Obispo
- Private suite rentals San Luis Obispo
- Kid-friendly rentals San Luis Obispo
- Apartment rentals San Luis Obispo
- Cottage rentals San Luis Obispo
- Rentals with a hot tub San Luis Obispo
- Beach house rentals San Luis Obispo
- Condo rentals San Luis Obispo
- Rentals with a fire pit San Luis Obispo
- Pet-friendly rentals San Luis Obispo
- Rentals with outdoor seating San Luis Obispo
- Rentals with a patio San Luis Obispo
- Rentals with beach access San Luis Obispo
- House rentals San Luis Obispo
- Rentals with breakfast San Luis Obispo
- Rentals with a washer and dryer San Luis Obispo
- Beachfront rentals San Luis Obispo
- Hotel rentals San Luis Obispo
- Rentals with an EV charger San Luis Obispo
- Guesthouse rentals San Luis Obispo County
- Guesthouse rentals California
- Guesthouse rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Cayucos Beach
- Cayucos State Beach
- Montaña de Oro State Park
- Morro Strand State Beach
- Natalie's Cove
- Dairy Creek Golf Course
- Hearst San Simeon State Park
- B & E Vineyard & Winery
- Moonstone Beach
- Pismo State Beach
- Mission San Luis Obispo de Tolosa
- Morro Bay Golf Course
- Spooner's Cove
- Allegretto Wines
- Pirates Cove Beach
- Morro Rock Beach
- Olde Port Beach
- Point Sal State Beach
- Baywood Park Beach
- Coon Creek Beach
- French Camp Vineyards
- Bovino Vineyards
- Seal Beach
- Bianchi Winery
- Things to do San Luis Obispo
- Things to do San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Food and drink San Luis Obispo County
- Things to do California
- Sightseeing California
- Food and drink California
- Entertainment California
- Wellness California
- Sports activities California
- Tours California
- Art and culture California
- Nature and outdoors California
- Things to do United States
- Food and drink United States
- Sightseeing United States
- Sports activities United States
- Entertainment United States
- Tours United States
- Art and culture United States
- Wellness United States
- Nature and outdoors United States