Guesthouse vacation rentals in San Luis Obispo
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Luis Obispo
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Luis Obispo guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Arroyo Grande
4.95 out of 5 average rating, 547 reviewsHidden oasis..escape to tranquility..
Oct 31 – Nov 7
Guesthouse in Morro Bay
4.88 out of 5 average rating, 612 reviewsPERFECT LIL SURF SHACK
Feb 9 – 16
Guesthouse in San Luis Obispo
4.85 out of 5 average rating, 393 reviewsThe Lincoln Street Cottage | SANITIZED & SAFE!
Jul 10 – 17
Guesthouse in Santa Maria
4.99 out of 5 average rating, 1445 reviewsFrench Country Casita - Breakfast Included
Oct 23 – 30
Guesthouse in Cayucos
4.98 out of 5 average rating, 614 reviewsCayucos Paradise in the Country
Jul 30 – Aug 6
Guesthouse in Morro Bay
4.94 out of 5 average rating, 448 reviewsMarshall's place; remodeled with bay view.
Nov 21 – 28
Guesthouse in San Luis Obispo
4.94 out of 5 average rating, 236 reviewsWine Country Casita
Nov 5 – 12
Guesthouse in Atascadero
4.96 out of 5 average rating, 113 reviewsWindmill Lane-Beautiful Country Tree-Lined Retreat
Jul 7 – 14
Guest house rentals with a patio
Guesthouse in Arroyo Grande
4.97 out of 5 average rating, 110 reviewsCentral Coast Guest House - Private entrance
Nov 7 – 14
Guesthouse in Baywood-Los Osos
4.98 out of 5 average rating, 114 reviewsCasita By the Sea: Secluded and Serene
Aug 12 – 19
Guesthouse in Templeton
4.96 out of 5 average rating, 122 reviewsSip and Stay: Countryside Paso Robles Wine Region
Dec 11 – 18
Guesthouse in Paso Robles
4.97 out of 5 average rating, 113 reviewsDeerfield Cottage on Paso's wine road
Oct 23 – 30
Guesthouse in Arroyo Grande
4.97 out of 5 average rating, 116 reviewsHummingbird Cottage: Private & Quiet Getaway
Jul 18 – 25
Guesthouse in San Luis Obispo
4.85 out of 5 average rating, 41 reviewsBright & roomy SLO Studio, 8 min walk to downtown
Jul 25 – Aug 1
Guesthouse in Atascadero
4.93 out of 5 average rating, 43 reviewsCentral Coast Casita
Apr 20 – 27
Guesthouse in Baywood-Los Osos
4.83 out of 5 average rating, 36 reviewsThe Shed
Jan 6 – 13
Guest house rentals with a washer and dryer
Guesthouse in Atascadero
4.92 out of 5 average rating, 193 reviewsHistoric 1919 carriage house
Dec 12 – 19
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 479 reviewsDowntown Historic District Sunset Studio
Jun 29 – Jul 6
Guesthouse in Atascadero
4.99 out of 5 average rating, 177 reviewsRomantic Getaway at a Guesthouse near Downtown Atascadero
Feb 17 – 24
Guesthouse in Arroyo Grande
4.9 out of 5 average rating, 221 reviewsHoney's Cottage
Jan 16 – 23
Guesthouse in Morro Bay
4.98 out of 5 average rating, 342 reviewsThe Little House
Oct 20 – 27
Guesthouse in Arroyo Grande
4.93 out of 5 average rating, 289 reviewsMesa View Ranch Lemons
Jun 21 – 28
Guesthouse in San Luis Obispo
5.0 out of 5 average rating, 109 reviewsDowntown SLO Abode- Walk downtown & close to Poly
May 14 – 21
Guesthouse in Arroyo Grande
5.0 out of 5 average rating, 121 reviewsCentral Coast Country Retreat
Dec 3 – 10
Quick stats about guesthouse rentals in San Luis Obispo
Total rentals
30 properties
Popular amenities
Kitchen, Wifi, and Pool
Wifi availability
30 properties include access to wifi
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Total number of reviews
4.9K reviews
Nightly prices starting at
€ 74 before taxes and fees
Destinations to explore
- Big Sur Vacation rentals
- Santa Barbara Vacation rentals
- San Jose Vacation rentals
- Santa Monica Vacation rentals
- Anaheim Vacation rentals
- San Diego Vacation rentals
- Palm Springs Vacation rentals
- Malibu Vacation rentals
- Beverly Hills Vacation rentals
- Los Angeles Vacation rentals
- Joshua Tree Vacation rentals
- San Francisco Vacation rentals
- Guesthouse rentals United States
- House rentals United States
- House rentals California
- Guesthouse rentals California
- House rentals Santa Barbara
- Guesthouse rentals Santa Barbara
- Pet-friendly rentals San Luis Obispo
- House rentals San Luis Obispo
- Hotel rentals San Luis Obispo
- Rentals with an EV charger San Luis Obispo
- Rentals with a hot tub San Luis Obispo
- Rentals with outdoor seating San Luis Obispo
- Rentals with breakfast San Luis Obispo
- Monthly Rentals San Luis Obispo
- Cabin rentals San Luis Obispo
- Cottage rentals San Luis Obispo
- Rentals with beach access San Luis Obispo
- Kid-friendly rentals San Luis Obispo
- Rentals with a patio San Luis Obispo
- Rentals with a fire pit San Luis Obispo
- Apartment rentals San Luis Obispo
- Rentals with pools San Luis Obispo
- Family-friendly rentals San Luis Obispo
- Rentals with a washer and dryer San Luis Obispo
- Rentals with a fireplace San Luis Obispo
- Private suite rentals San Luis Obispo
- Guesthouse rentals Big Sur
- House rentals Big Sur
- Guesthouse rentals Montecito
- House rentals Montecito
- Guesthouse rentals San Luis Obispo County
- House rentals San Luis Obispo County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom