Vacation rentals in San Luis Obispo

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Top-rated vacation rentals in San Luis Obispo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.
Guesthouse in San Luis Obispo
4.97 out of 5 average rating, 620 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Top guest favorite
A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.
Home in San Luis Obispo
4.99 out of 5 average rating, 123 reviews

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

Guest favorite
A vintage-inspired kitchen features white cabinetry and open shelving displaying a variety of decorative dishware. A well-appointed stove and sink are included, along with subtle decor elements such as potted plants and a floral arrangement, creating a warm and welcoming environment.
Apartment in Downtown SLO
4.98 out of 5 average rating, 306 reviews

Eclectic apartment in the heart of downtown SLO.

This charming, newly updated, 1 BR apartment is part of an 1883 Folk Victorian in the heart of SLO's downtown historic district and was recently added to the California Master List of Historic Resources as 'The D.M. & Carrie Proper Meredith House'. This cozy apartment offers convenience, style, safety, and privacy - all while being just a two-minute walk to all your favorite bars, restaurants, cafes, movie theatres, and shops. Your hosts aim to provide you with an amazing 5-star experience!

Top guest favorite
A spacious bedroom is equipped with a large bed draped in a decorative quilt, complemented by colorful pillows. Two bedside tables with lamps are placed beside the bed. A small dining table and chair set sits by a window, allowing natural light to illuminate the room.
Apartment in San Luis Obispo
4.97 out of 5 average rating, 363 reviews

Mountain View Studio - No Cleaning Fee!

Your home away from home is close to Cal Poly, hiking, art and culture, great views, restaurants, wineries, and several beaches. This spacious studio apartment has a super-comfy bed and is located in a quiet neighborhood with easy access to all things SLO. We use only natural, organic cleaning products, and all sheets and towels are of high-quality cotton. Kitchenette stocked with coffee, tea, etc. Smart TV. Licensed in the city of SLO ( #113984), so a required 13% lodging tax is included.

Top guest favorite
Barn in Atascadero
4.99 out of 5 average rating, 192 reviews

The Barn at Old Morro

The Barn at Old Morro is a refreshing and beautiful space centrally located to all the Central Coast has to offer! Tastefully appointed and well stocked, the barn is the perfect getaway for Paso Robles wine country, the Cayucos/Cambria/Morro Bay Coast, San Luis Obispo shopping or exploring the gorgeous Big Sur coastline! Set in a beautiful spot at the lower end of our property under a mature and majestic grove of oak trees with overhead twinkling bistro lights.

Guest favorite
A charming Craftsman home is presented with a welcoming front porch. Stone accents and vibrant greenery surround the entrance, adding character to the exterior. The clean lines of the architectural features are complemented by large windows that allow natural light to fill the interior.
Bungalow in Downtown SLO
4.93 out of 5 average rating, 124 reviews

Cozy Historic Craftsman Bungalow

Located in SLO's Old Town Historic District, featuring beautifully restored Victorian and Craftsman homes, this two bedroom Craftsman is less than a 5 minute walk to downtown shops/restaurants/nightlife. Despite its central location, the house is situated on a quiet street without heavy traffic. The property includes a private yard with a large (8 person) hot tub and grill. The kitchen is well stocked with everything you need for gourmet or casual cooking.

Guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 344 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Top guest favorite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in Downtown SLO
4.96 out of 5 average rating, 424 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 264 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favorite
The exterior of the handcrafted timber-frame barn is presented, featuring a set of stairs leading to the entrance. Decorative railings adorn the upper level, while a small seating area with a round table and chairs is visible in the foreground. Surrounding trees add greenery to the landscape.
Barn in San Luis Obispo
5 out of 5 average rating, 124 reviews

Loft in Barn on Olive Farm

This beautiful loft apartment is located in a handcrafted timber-frame barn. Many artistic touches make this space cozy and unique. Surrounded by oak trees and gorgeous landscape, this setting is a perfect getaway spot. Whether you choose to unwind in the serenity that surrounds our olive farm or venture out to experience all that SLO County has to offer, you'll be in the perfect spot.

Top guest favorite
A cozy studio space is presented with a spacious bed adorned in white bedding. A rattan chair is positioned next to a large window offering natural light, while a small table rests nearby. A decorative wall piece adds a touch of personality to the room.
Guest suite in San Luis Obispo
4.92 out of 5 average rating, 446 reviews

Harris House

A private 250 sq/ft studio space right in downtown San Luis Obispo. Located in an updated 1935 home, the private entrance leads you upstairs to your own space complete with bathroom, reading nook, and kitchenette area with a microwave, electric kettle, mini refrigerator, and pour over coffee. This is a great launching pad for exploring all around San Luis Obispo.

Top guest favorite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 125 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Popular amenities for San Luis Obispo vacation rentals

When is the best time to visit San Luis Obispo?

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Frequently Asked Questions

  • Where should I stay in San Luis Obispo?

    Make yourself at home in San Luis Obispo by choosing from our most frequently booked neighborhoods. We have over 370 vacation rentals in Japantown, over 370 vacation rentals in Meadow Park, and over 370 vacation rentals in Downtown SLO.

  • Are there vacation rentals with a dedicated workspace in San Luis Obispo?

    Yes! Work meets play with ease at over 200 vacation rentals in San Luis Obispo featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis Obispo?

    Four-legged friends are welcome in San Luis Obispo. Choose from more than 110 vacation rentals for guests traveling with pets.

  • Are there San Luis Obispo vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 30 vacation homes with pools in San Luis Obispo, available on Airbnb. Make a splash and soak up the sun in style!

  • How much does it cost to stay in guesthouse rentals in San Luis Obispo?

    Experience the best of San Luis Obispo with our guesthouse rentals, starting at about $80 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there family-friendly vacation rentals in San Luis Obispo?

    San Luis Obispo has more than 170 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do house rentals in San Luis Obispo have a bbq area?

    Absolutely! We offer over 50 house rentals with a bbq area in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis Obispo have self check-in?

    Absolutely! We offer over 60 house rentals with self check-in in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • Do hotel rentals in San Luis Obispo have a gym?

    Absolutely! We offer over 10 hotel rentals with a gym in San Luis Obispo. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for House Rentals in San Luis Obispo?

    Enhance your stay in our House Rentals with the most popular amenities: over 50 homes with a bbq area, over 60 homes with self check-in, and more. Indulge in the ultimate retreat, tailored to your preferences.

All about San Luis Obispo

An equal distance from the wildlife haven of Morro Bay and laid-back Pismo Beach, the small city of San Luis Obispo sits midway between Los Angeles and San Francisco in California’s central coast region. As one of the state’s oldest communities, it’s filled with culture and history, featuring a 19th-century city center surrounded by a restored 18th-century mission, and local homes and businesses often have a Spanish architectural influence.

Aside from dreamy views of the Santa Lucia Mountains and coastline, a major draw in San Luis Obispo is its location in the state’s third-largest wine-producing county, and you can pair your local albariño with dinner made with ingredients sourced from the numerous local farmers markets. Vacation homes here are also well positioned for exploring the local art scene — you’ll find pop-up galleries sitting alongside permanent exhibitions — and kayaking, swimming, and hiking are all within easy reach.

What are the top things to do in San Luis Obispo?

Edna Valley

Just a short drive south from San Luis Obispo is Edna Valley, a region known for its cluster of wineries and award-winning pinot noir — you’ll find established brands and under-the-radar producers offering tastings at their vineyards. Visit the Old Edna Townsite for a picnic with wine and cheese or nearby Arroyo Grande Valley to browse the local markets.

San Luis Obispo Museum of Art

Perched on Monterey Street downtown, the San Luis Obispo Museum of Art showcases California artists across three galleries, focusing on contemporary works. Head to SLOMA, as the locals call it, for a taste of local prints, sculptures, and paintings. If you time your visit right, you can join one of the monthly talks that take you through the exhibits.

Montaña de Oro State Park

Ten miles west from the city is Montaña de Oro State Park, a popular spot thanks to its abundance of trails for cyclists and hikers, beautiful peaks, and sandy beach. Nature lovers are also drawn here for the seabirds and otters. Take one of the coastal trails by Spooner’s Cove for views of the ocean and unique rock formations.

Quick stats about vacation rentals in San Luis Obispo

  • Total vacation rentals

    Explore 400 vacation rentals in San Luis Obispo

  • Verified guest reviews

    Over 39,400 verified reviews to help you choose

  • Family-friendly vacation rentals

    170 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 110 rentals that welcome pets

  • Vacation rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    200 properties have a dedicated workspace

  • Wi-Fi availability

    390 of San Luis Obispo vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Self check-in, Beachfront, and Gym across San Luis Obispo rentals

  • 4.9 Average rating

    San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!

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