Villa vacation rentals in Panama City

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Top-rated villa rentals in Panama City

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Superhost

A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.

Villa in Panamá

4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Guest favorite

A tranquil beachfront scene features several hammocks strung between palm trees on soft sand. Blue lounge chairs are positioned alongside the water, with gentle waves lapping at the shore under a clear sky.

Villa in Chame

4.86 out of 5 average rating, 230 reviews

Surf Relax Play Pacific Ocean View Villa

White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Superhost

The outdoor area features a swimming pool with sun loungers arranged around it. Umbrellas provide shade, and the surrounding greenery enhances the space. In the background, the ocean and sky create a scenic backdrop, with the villa positioned to the left.

Villa in Chame

4.84 out of 5 average rating, 111 reviews

Ocean Pergola Villa (C10-PBB) 2 bed, 2 bath

Unique place steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

Top guest favorite

A modern outdoor area features a turquoise swimming pool surrounded by lush greenery. The space includes a partially covered patio with seating options and an outdoor bar area. Tall buildings are visible in the background against a clear blue sky.

Villa in Santa Cruz De Chinina

5 out of 5 average rating, 24 reviews

5BR House in Panama City w/ Pool & King Beds

Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

Guest favorite

A multi-story mansion is showcased overlooking a vibrant swimming pool, adorned with inflatable toys including a pink flamingo and a whale. Bright umbrellas provide shade over red loungers, all set against a backdrop of lush greenery and a partially cloudy sky.

Villa in Panamá

4.97 out of 5 average rating, 59 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

A large pool serves as the centerpiece, surrounded by lounge chairs and shaded by a large umbrella. Lush greenery and vibrant flowers border the area, enhancing the tranquil atmosphere. Visible in the background are palm trees and clear blue skies.

Villa in Santa Cruz De Chinina

4.9 out of 5 average rating, 31 reviews

Beachfront 5BR Villa in Punta Chame ~Pool ~Rooftop

Relax in this spacious beachfront villa with a private pool, rooftop terrace, and palm-lined path straight to the beach. Perfect for families, groups, or special events — whether you’re sharing BBQ nights, watching sunsets on the rooftop, or simply soaking up the tropical atmosphere. Just 2 hours from Panama City and 5 mins to Punta Chame Beach! • Beachfront Villa with Direct Access • Private Pool + Palm Garden • Rooftop with 360° Sunset Views • Fast Wi-Fi & Dedicated Workspace

Guest favorite

A spacious swimming pool is framed by lounge chairs, with a bright pink float positioned in the water. The villa's exterior is visible in the background, showcasing a large parking area and covered terrace with a red roof, surrounded by greenery.

Villa in Portobelo

4.92 out of 5 average rating, 25 reviews

Villa with a swimming pool, soccer field, and stream

Quiet and spacious villa in Portobelo, Buenaventura. Enjoy a villa with a giant garden, river, soccer court, pool with waterfall and slide , 2 boyos, barbecue areas, terrace. 1 Master Bed with King Bed and Private Bathroom 2 bedrooms with 2 full beds. 1 bathroom in the room. 1 bathroom in the pool area and external shower. Living Room, Dining Room. Cable TV. Equipped kitchen. Hammocks. * The house is equipped with beds for 10 people, bring air mattresses with sheets.

Top guest favorite

A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.

Villa in Portobelo

5 out of 5 average rating, 74 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favorite

The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.

Villa in Santa Cruz De Chinina

4.97 out of 5 average rating, 132 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favorite

A bright living area features a neutral-colored sofa adorned with a decorative throw. A round coffee table occupies the center, while a television is mounted on a wooden accent wall. A dining table with black chairs is visible in the background, along with an open kitchen.

Villa in Chame District

4.97 out of 5 average rating, 30 reviews

Villa Playa Caracol, 3 Bedrooms, Pet Friendly

¡Welcome to your perfect beach getaway! This charming ground-floor villa awaits you just 100 meters from the golden sand and refreshing waves of the sea. This home offers an ideal retreat for families and groups of friends looking to relax and enjoy the sun and sea breeze. Enjoy the pool right in front of the villa, where you'll also find a playground for everyone to enjoy. ¡Book now and experience a dreamy seaside vacation!

The villa features an expansive front facade, showcasing a blend of architectural styles with arched windows and a tiled roof. Lush palm trees frame the entrance, enhancing the peaceful ambiance. A paved driveway leads to the open carport on the left.

Villa in Mechi

4.6 out of 5 average rating, 15 reviews

Caribbean Beach House with Pool

Perfect location for family gatherings in a gated community , 24 hour security , beautiful villa with Pool . 200 meters from beach. Located one hour , 15 minutes away from international Airport . Located 50 minutes away from Portobelo. 5 minute drive from playa Angosta and twenty five minutes away from Isle Grande. Minutes away from the best scuba diving excursions on the Caribbean coast.

Top guest favorite

A cozy bedroom features a spacious bed with a patterned coverlet, complemented by a bedside table and a lamp. A wardrobe is positioned nearby, and curtain panels frame the window, allowing natural light to filter in. The minimalist decor creates a serene atmosphere.

Villa in Panamá

5 out of 5 average rating, 13 reviews

Villa Helena Studio 1 Apt Cerro Azul

One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.