Vacation rentals in Osborn Medical Center, Phoenix

4.93 out of 5 average rating, 804 reviews

A light-filled living area features a modern gray sofa paired with a textured black and white rug. A minimalist coffee table rests in front, while a sleek kitchen is visible in the background with bar seating. A vibrant piece of art adorns the wall, adding character.

Home in Encanto

Relax in an Elegant and Bohemian Phoenix Bungalow

This home was initially built in 1943 and has since been completely gutted with all new building systems, finishes, windows, doors, the works! We want to ensure our guests are as comfortable as possible with amenities like Hilton-standard Serta mattresses, Nespresso machine, and Apple TV for streaming Netflix and cable programs. We also strive to include local touches including a rotating art gallery of local artists. Guests will also be in walking distance to more than five local restaurants. Guests have access to the entire property. We love getting to know our guests. Should you need to know where the best restaurants in town are, coffee shops, things to do just ask and we will be happy to provide you with all our favorite places in Phoenix. Coronado Historic District is home to a warm and quiet community of young families, artists, and Phoenix natives with several restaurants and coffee shops within walking distance. Entry into the home is gained via a digital lockbox. A unique code will be given to each guest via email just one hour prior to check in. We kindly ask that guests inquire with us regarding holding any sort of photo shoot, event or party at the Coronado Casita prior to their stay. If a different check-in or checkout time is desired, please consult with us upon booking. We will need to coordinate with our cleaning crew in order to accommodate you and need time to do so.

A historic guesthouse is framed by a mix of stone and soft greenery. The outdoor area features a stone pathway, bordered by low shrubs, leading to a covered seating area under a wooden gazebo. Sunlight fills the scene, highlighting the inviting residence.

4.96 out of 5 average rating, 183 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

The interior space features an open layout with a cozy sitting area, including a brown couch adorned with white pillows, and a coffee table. The kitchenette is equipped with a refrigerator and modern cabinetry. Natural light enters through large windows, enhancing the warm ambiance.

4.98 out of 5 average rating, 105 reviews

Spacious Midtown guesthouse with full privacy

Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

4.98 out of 5 average rating, 252 reviews

A well-furnished living room features a comfortable gray sofa and a light blue accent chair. Natural light enters through the white-framed windows, illuminating a colorful artwork hung on the wall. A modern ceiling fan and a glass-top side table with decorative items enhance the inviting atmosphere.

Home in Encanto

No Cleaning Fee!-Midtown Oasis-Great Outdoor Space

Perfectly located, this Central Phoenix retreat is a remodeled, immaculately kept, Central Phoenix home built in 1944. It is beautifully furnished with everything you need for a comfortable stay. Included is a relaxing outdoor space to enjoy morning coffee or BBQ dinner. It is on a quiet street on the grand canal, walking distance to the light rail, restaurants, cafes, bars, museums, Steele Indian School Park (one of the largest parks in Phoenix), and all the attractions in downtown Phoenix.

A bedside table features a Smart Home device, providing convenient voice control. The stylish headboard frames a spacious bed adorned with crisp white bedding. Soft lighting enhances the clean and modern decor of the room, creating an inviting atmosphere.

4.97 out of 5 average rating, 191 reviews

PHX's Modern Midtown Carriage House, Free Parking

Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious queen bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

A swimming pool surrounded by a white wall features a pebble tech finish. Two lounge chairs are positioned on the edge of the pool, with green grass along one side. Bright sunlight reflects off the water, creating a shimmering effect.

4.96 out of 5 average rating, 110 reviews

Poolside Guesthouse with Private Patio in Midtown

Welcome to the Poolside Guesthouse! Everything has been designed with you in mind to help you enjoy your time in Phoenix! Furniture and fixtures have been selected for your comfort and to help maximize the space. The Poolside Guesthouse has fantastic outdoor spaces for you to enjoy our beautiful weather & offers one of the best central locations with easy access to the airport, shopping, arts district, museums, bars and restaurants. TPT License #21525000 City of Phoenix License #2023-4161

The exterior of a charming studio guesthouse is visible, showcasing a brown brick facade and a well-kept entrance. A small pathway leads to the door, and palm trees can be seen in the background against a bright blue sky.

4.97 out of 5 average rating, 1,242 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

4.99 out of 5 average rating, 334 reviews

A cozy bedroom featuring a spacious bed with a custom leather headboard. A large black and white mural of cacti adds character to the room. A modern pendant light hangs above, complementing the warm tones of the wooden bed frame and the textured beige bedding.

Guest suite in Encanto

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

A communal living space features a comfortable sofa adorned with various textured cushions. A chalkboard wall displays creative messages, while a vibrant red kitchen cabinet adds visual interest. Sunlight enters through double French doors, enhancing the overall ambiance.

5 out of 5 average rating, 351 reviews

Urban Green House The Garden House

The Urban Green House brings farm life to the urban core. We offer fresh eggs from our backyard hens and gardens for guests to enjoy. We also live green-using solar panels, recycling, and composting. Sarah and Ryan live locally and are available to meet any needs that arise. We are located in a quiet and safe 1950s neighborhood, close to local restaurants, coffee shops, Encanto park, direct access to both the I-10 and I-17 freeways, and only 8 miles from Phoenix Sky Harbor Airport.

Guesthouse in Central City

The studio features an open layout with a spacious bed dressed in crisp linens. A small kitchen area equipped with a refrigerator and induction cooktop stands adjacent to a dining space with bar stools. Large sliding doors open to a private outdoor patio with a stone pathway.

4.94 out of 5 average rating, 1,022 reviews

Studio B industrial design

A contemporary industrial designed studio with sealed distressed cement floors and exposed pipes. A grey water system irrigates the lush southwest gardens. Be adventurous and choose the outdoor shower in the enclosed back patio to fully appreciate the warm weather! Tucked away in the historic F.Q. Story Neighborhood in downtown Phoenix. You are surrounded by charming historic homes as you walk the neighborhood. Close to local eats, parks, and museums. EVERYONE is welcome at Studio B!

4.89 out of 5 average rating, 1,002 reviews

An outdoor seating area is shaded by a large red umbrella. A round table with two chairs is accompanied by a cushioned chair, surrounded by vibrant flowering plants. A small statue and a chalkboard are visible against the textured wall, enhancing the inviting ambiance.

Cottage in Encanto

Private studio cottage, charming, downtown

This is a 100 year old quaint historic home located in downtown Phoenix area. Encanto Park established in 1935 is right across the street, enjoy the duck ponds, paddle boating, 18 hole Encanto golf course within walking distance, Pool directly across the street during summer only. friendly park and neighborhood! Bikes are available for borrowing. Several restaurants, museum, theatre within 2 miles. Sky Harbor Airport within 7 miles, Highway I17, I10 within 2 miles.

A cozy studio space is featured, showcasing a queen bed with plush pillows and a decorative headboard. A small dining area with elegant plates is positioned nearby, complemented by a kitchenette stocked with essential items. Light fixtures add a subtle ambiance to the room.