Vacation rentals in Issaqueena Falls

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Issaqueena Falls

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Guest favorite
An aerial view of the modern cabin, surrounded by vibrant fall foliage. The expansive deck features a hot tub and various seating areas, with a stunning landscape of trees and mountains in the background, demonstrating a seamless connection to nature.
Shipping container in Clarkesville
4.94 out of 5 average rating, 116 reviews

Oakey Mountain Mirror Haus

Nestled in the heart of Clarkesville, GA, Oakey Mountain Mirror Haus offers a tranquil escape where nature meets modern luxury. This cozy, thoughtfully designed tiny home is a haven for those seeking serenity. With reflective exterior walls that blend seamlessly into the lush forest surroundings, you’ll feel at one with nature while enjoying upscale amenities. Perfect for couples or solo travelers, this unique retreat invites you to unwind, recharge, and connect with the beauty of the mountains.

Guest favorite
A custom-built cabin is positioned under a canopy of trees, with a spacious porch extending towards the serene lake. The natural wood exterior complements the surrounding greenery, while the tranquil water reflects the blue sky and foliage. A gravel path leads up to the entrance.
Cabin in Mountain Rest
4.87 out of 5 average rating, 157 reviews

Mountain Cabin w/ Hot Tub + Pvt. Deck

*** Due to urgent dam repairs, the lake will be drained and not usable from June 15, 2026 through May 2027.*** An adventurous holiday at this phenomenal charming rustic custom-built cabin in a private, gated community! This outdoorsy getaway is close to many outdoor opportunities like hiking and biking trails and fly fishing. There is also a fire pit, fireplace, hot tub, and deck! When you're not soaking up the sun curl up on the hammock and relish the peace and quiet of this secluded property.

Top guest favorite
The treehouse rests elevated among dense trees, featuring a wooden deck with railing and steps leading to the ground. A circular stone fire pit is located at the base, surrounded by gravel, providing an inviting outdoor gathering space.
Treehouse in Seneca
5 out of 5 average rating, 74 reviews

Treehouse at Keowee Hollow

Welcome to the treehouse at Keowee Hollow!!! A CHARMING space nestled in a hollow - with a view of Lake Keowee - perfect for a ROMANTIC getaway or a peaceful retreat. This COZY, brand new, 1 bedroom, 1 bath treehouse offers rest and relaxation. Perfect location. We are minutes from Seneca, 10 miles from Clemson, under an hour to downtown Greenville, Highlands or Cashiers. The outdoor seating area is a perfect place to unwind at the end of a busy day, also features a fire pit & outdoor grill.

Guest favorite
Dome in Salem
4.88 out of 5 average rating, 392 reviews

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Top guest favorite
A spacious deck features two wicker chairs overlooking a panoramic view of rolling green mountains. The horizon is defined by soft peaks and valleys under a clear blue sky, creating a serene outdoor space perfect for relaxation.
Cabin in Sylva
5 out of 5 average rating, 41 reviews

NC Mountain Escape (4x4 or AWD)

Enjoy some of the best views of Western NC mountains in this modern well-equipped cabin. RELAX and take in the scenery in all directions while enjoying a cup of coffee, glass of wine, star gazing, or just sitting around the campfire. Situated near many popular destinations and towns if wanting to explore. Opportunities near by for rafting, hiking, waterfalls, antiquing and scenic drives. One hour away from Smoky Mountain National Park. 2br/ 2bath and one game room 4x4 or AWD vehicles required

Top guest favorite
Home in Walhalla
4.98 out of 5 average rating, 93 reviews

Valhalla: Cliff-Edge Suite · Forest Views · Tub

VALHALLA – The Ultimate Romantic Retreat 🏔️🥂✨ Perched above it all, Valhalla is romance elevated. Sip cocktails at your private sky bar with jaw-dropping mountain views that stretch for miles. Soak in a clawfoot tub with breathtaking scenery right outside your window. Snuggle up for movie nights on the large screen TV. Fall asleep under the stars, wake up to misty mountain mornings. 💕 Add champagne, wine & chocolates to make it unforgettable. (upon request for an additional charge)

Top guest favorite
A vibrant scene showcases two golden retrievers playing in a shallow stream, surrounded by lush green foliage. Behind them, a cascading waterfall flows over rocky tiers, creating a soothing sound and enhancing the natural beauty of the forested landscape.
Cabin in Oconee County
4.99 out of 5 average rating, 393 reviews

Secluded Waterfall Cabin.

Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

Top guest favorite
Cabin in Clayton
5 out of 5 average rating, 249 reviews

Luxury Cabin- Hot Tub/Mtn Views/Min to Clayton

Sassy Cabin is a stunning mountain retreat just minutes from downtown Clayton—yet feels a world away. Set on a private, wooded lot with gorgeous views from every window, this professionally designed retreat invites you to relax and recharge. Soak in the hot tub beneath the stars, relax under magical outdoor lighting, and enjoy serene, minimalist interiors that let nature take center stage. Easy access w/ all paved roads. Three bedrooms, all with private bathroom. Fully loaded for kids + pets.

Top guest favorite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5 out of 5 average rating, 482 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Top guest favorite
A charming cabin is nestled among tall trees, accessed by a stone path. Warm string lights adorn the porch area, creating a welcoming glow. Fallen leaves blanket the ground, complementing the natural surroundings and inviting a sense of tranquility.
Cabin in Pickens
4.98 out of 5 average rating, 299 reviews

The Romantic Greystone Cottage

Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Top guest favorite
Home in Lake Toxaway
4.99 out of 5 average rating, 374 reviews

Cabin I Private hiking trails | Hot Tub I Sauna

Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Guest favorite
Home in Westminster
4.94 out of 5 average rating, 300 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Popular amenities for Issaqueena Falls vacation rentals