
House vacation rentals in Guadalupe
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Top-rated house rentals in Guadalupe
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Luxury Surfhouse 5Min to Pismo Walk to Restaurants
Modern open-air retreat, minutes from Pismo Beach and walking distance to restaurants, shops, coffee and entertainment. Bright and spacious, our Airbnb was carefully designed for comfort and connection, wrapped in a coastal luxury vibe. Families love the surf lounge, games, fire pit, and beach gear. Our one-of-a-kind Airbnb is fully stocked with everything you need, making your stay relaxing and stress-free. With a short drive to SLO or Avila, your next unforgettable coastal getaway begins here.

Beach-themed farmhouse with indoor fireplace
As 13-time Superhosts- we welcome you to the perfect place to relax & unwind after your day. This stylish and spacious home offers a sunny deck, surrounded by trees for sunbathing or watching the sunset. The huge 2nd bdrm is a great place for reading in our hammock chair or for a quiet work space. Downstairs the fully equipped kitchen has everything you need for cooking meals. Outdoor patio is a nice place to bbq & relax as you listen to the hawks, owls, & other birds in this country setting.

Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Hillside view with hot tub too
This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.

Gateway to SLO County with Pickleball & Game Room
Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

Casa Del Mar
Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Bungalow by the Bay
Our cute & rustic Single Bungalow is seen in the background behind the red Bougainvillea flowers. We're in an excellent quiet location, just one block from the Bay, Audubon Lookout, Farmers Market, and unique restaurants. Only a five-minute drive to the MUST-SEE Montana de Oro State Park. We include kayaks, family bikes, and a private little deck with a Weber grill. Check out our YouTube Videos; "Los Osos Tourism Advertisement" and "Quirk - Nine Palms". Sorry no pets

Pleasant hills, king suite, EV Charger
Come relax and enjoy our peaceful home and outdoor spaces. We are located halfway between Los Angeles and San Francisco. Here you can experience the beautiful Central Coast including wineries, Beaches, Cal Poly and golf courses. We are located in a quiet neighborhood adjacent to an organic blackberry farm. Easy access to the 101 Freeway, where you can easily visit Santa Barbara or Paso Robles wine regions. Our home is FULLY Air Conditioned for your comfort.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Garden Room Central Coast Wine Country
Lovely private one bedroom with private entrance and contactless check-in, private bath and kitchenette, in one of the original Victorian homes of Lompoc built in 1879. The renovated landmark is set in a spacious, quiet, beautifully manicured Victorian Gardens in the heart of Central Coast Wine Country! (No pets.) Two triplexes with six renters are also on property.

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views
Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge
Popular amenities for Guadalupe house rentals
House rentals with a pool

Indoor Private Pool Close to the Beach

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious 4bd Home w/ Pool, Spa. Pet Friendly!

Fairway to Heaven

Mountain Sanctuary, Saltwater Pool

Getaway at the Highlands+Heated Pool+Hot Tub

FairView Lavender Estate
Weekly house rentals

Western Village

Pacific Coast Highway Milkhouse

Back Bay Getaway - Dog Friendly - Home in Los Osos

Beach, Wine Country, & Golf adjacent home for 8

Luxury Village Home

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views

The Downtown House SLO with Private Parking

Coastal cottage in Pismo beach
Private house rentals

Centennial House - Old West meets Modern Farmhouse

Family Retreat | Stunning Views | Modern Amenities

Cozy Plant-Filled Loft in Orcutt

Pelican Cove Vacation Rental at the Back Bay

1 Block from Beach with long driveway for parking

Elegant retreat on the Central Coast

Blue Wave of Avila

Family Home with Playground close to Beach
Destinations to explore
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- Cayucos Beach
- Captain State Beach
- Montaña de Oro State Park
- Natalie's Cove
- Arroyo Quemada Beach
- Gaviota Beach
- Morro Strand State Beach
- B & E Vineyard & Winery
- Refugio Beach
- Cayucos State Beach
- Mission San Luis Obispo de Tolosa
- Dairy Creek Golf Course
- Morro Rock Beach
- Seal Beach
- Pirates Cove Beach
- Morro Bay Golf Course
- Sand Dollars
- Point Sal State Beach
- Spooner's Cove
- Baywood Park Beach
- Olde Port Beach
- Allegretto Wines
- Bianchi Winery
- Bovino Vineyards




