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Vacation rentals in Guadalupe

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Guadalupe

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A modern living area features a cozy gray couch with decorative cushions, accompanied by a small circular table. Framed artwork adorns the white walls, and natural light brightens the space. A bar with two stools is visible, leading into a kitchen area.
Tiny home in Guadalupe
4.85 out of 5 average rating, 65 reviews

Cozy Tiny House Near The Beach

Consider this studio your home away from home while you visit the BEAUTIFUL Central Coast. This cool and pleasant space features 1 queen bed in the bedroom and a cozy living room with a couch that can sleep an additional guest(s). The Living room and bedroom are equipped with 50-inch TV' connected to the Wi-Fi for YouTube etc. Enjoy the convenience of a shower, hair dryer, iron and Wi-Fi during your stay. The unit you will be staying in is equipped with a full kitchen. Dining table/Island for 2.

Guest favorite
Apartment in Santa Maria
4.89 out of 5 average rating, 104 reviews

Pet Friendly, Centrally Located w/ Shared Gym

Welcome to The Jungalow, a beautiful 1 bed/1bath apartment style home nestled in the “Loft District'' of Santa Maria! This home features an inviting bedroom and a spacious living area with ample natural light. You are minutes away from the 101, shopping, and local restaurants. Santa Maria is centrally located, just an hour from Santa Barbara and about 30 mins from San Luis Obispo, Solvang & Chumash Casino! Enjoy being close to beautiful beaches, hiking trails, golf courses & renowned wineries.

Guest favorite
Apartment in Guadalupe
5.0 out of 5 average rating, 10 reviews

All-Inclusive | Private Entry | Full KTCHN + W/D

All-Inclusive Pricing – Save on the Airbnb Service Fee. Travel Nurses, Military (Vandenberg SFB), & Contract Workers. Located off Highway 1 for quick access to Santa Maria/Lompoc. Secure parking, in-unit laundry, and fast Mbps WiFi."Ideal private home for Travel Nurses on assignment. We offer blackout curtains for day sleepers and "Perfect for Vandenberg Military TDY personnel. Quick 27-min commute to the gate. Enjoy the convenience of fully stocked kitchen for your long-term, 28+ night stay.

Guest favorite
A spacious kitchen area features rich wooden cabinetry and a large gas range beneath a sleek exhaust hood. A mosaic tile backsplash adds texture, while natural light streams in through nearby windows, illuminating the granite countertops and various kitchen appliances.
Home in Arroyo Grande
4.91 out of 5 average rating, 170 reviews

Beautiful Country Home

Bring your family and friends to this beautiful, country Home just ten minutes from the beach. Rancho de la Cabeza is a peaceful, rustic ranch nestled between world class wineries, orchards, farms, golf courses, and the amazing beaches on the Central Coast! Are you looking to host a larger group? We have a smaller house on the same property. Both houses combined can sleep 18 people. Up to two dogs are allowed. $25 per pet fee. Smaller house: airbnb.com/h/central-coast-peaceful-haven

Top guest favorite
A vibrant backyard playground features a converted lifeguard tower, providing a unique play area above. Below, a ball pit filled with blue balls awaits playtime, while bubbles drift through the air. The space is surrounded by green turf, enhancing the playful atmosphere.
Home in Arroyo Grande
4.98 out of 5 average rating, 105 reviews

OMG Playground, close to Beach, Family Fun

Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.

Superhost
A modern living room features a dark blue sectional sofa accompanied by two light-colored armchairs. A large television is mounted on the wall opposite the seating area. Natural light enters through a window adorned with white blinds, and decorative lamps provide additional illumination.
Guesthouse in Santa Maria
4.84 out of 5 average rating, 101 reviews

Modern Guest House, 20 Min. Pismo Beach & Wineries

Welcome to our beautiful 2-bedroom, 1-bathroom guest house in the heart of Santa Maria! Nestled in a safe residential neighborhood, our brand new construction guest house is the perfect retreat for families and friends looking to explore the local wineries and vineyards or simply enjoy some beach days. The guest house offers a prime location, minutes away from the 101 freeway, making it easily accessible for our guests. Book your stay with us today and let us exceed your expectations!

Top guest favorite
A spacious living area features a large sectional sofa in dark leather, situated near multiple windows allowing natural light. A wooden coffee table is placed at the center, accompanied by decorative items. A flat-screen TV is mounted on the wall, adding to the entertainment space.
Guesthouse in Santa Maria
4.97 out of 5 average rating, 156 reviews

Private top floor spacious 1 bedroom retreat

Forget your worries in this spacious and serene space. Following CDC guidelines, we make sure your stay is a safe & enjoyable one. Equipped with a gas range stove, microwave, and washer/dryer. Relax in a full size tub, walk-in closet & plenty of space to store your items & gear. Enjoy hiking, biking & disk golf at near by Waller Park! Private entrance & exit. Please read our rules below before booking: 2 guests max 1 car parking No Parties No Smoking No Pets Additional fees may apply

Top guest favorite
A single-story ranch house features a red-tiled roof and white stucco walls. Flanked by several trees, the entrance is accentuated by wooden double doors. The sky above is clear with soft clouds, contributing to the serene outdoor setting.
Home in Nipomo
4.9 out of 5 average rating, 176 reviews

Working Ranch~Golf, Beach,Wine/No smoking/Pet free

***At this time we are not set up to host weddings or public events.*** Escape the city to this ranch retreat surrounded by working farms. This 3-bedroom, 4-bath vacation home is on a full-time ranch in the heart of California’s Central Coast, halfway between Los Angeles and San Francisco, just 2 miles from Highway 101. Golf, wineries, and hiking are minutes away. Avila Beach, Pismo Beach, Cal Poly and San Luis Obispo are a 15–20 minute drive. Stays of 30+ days available upon request.

Guest favorite
Home in Santa Maria
4.92 out of 5 average rating, 26 reviews

2-Story Gem by the Coast & Vines

Unwind in this stylish 2-story gem in Santa Maria—ideally located between scenic beaches and Central Coast wine country. This spacious and thoughtfully furnished home offers comfort, convenience, and charm for families, couples, or remote workers. Enjoy cozy bedrooms, a full kitchen, reverse osmosis water filter, fast Wi-Fi, gas grill, a private outdoor space, patio table, and easy access to local wineries, restaurants, hiking, and more. Your perfect California getaway starts here.

Guest favorite
A clean, lightly decorated living area is shown, featuring a neutral-colored sofa adorned with plush, blue-accented pillows. A wooden coffee table sits in front, complemented by a decorative arrangement of flowers and candles. Soft lighting enhances the serene ambiance of the space.
Apartment in Arroyo Grande
4.93 out of 5 average rating, 94 reviews

The Loft at Callender Cove

As 23-time Superhosts we invite you to rest and relax in comfort and style. This beautifully furnished & squeaky clean apartment is comfortable, quiet & decorated in calming beach decor. You will love the upstairs view of the country & eucalyptus trees. Safe location with a separate & private entrance. The home is fully furnished with all kitchen supplies you could need including coffee maker, Britta filter, dishes, silverware, pots, pans, etc. Not child friendly for many reasons.

Top guest favorite
A well-appointed sleeping area features a spacious bed dressed in a light-colored patterned coverlet. Stylish decorative pillows are arranged neatly at the head of the bed. A round table with a single chair sits nearby, surrounded by floral drapes that frame the window.
Guesthouse in Santa Maria
4.99 out of 5 average rating, 1738 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Superhost
A modern two-story home is depicted, showcasing a light-colored exterior with dark trim. The front yard features low-maintenance landscaping with desert plants. A driveway leads to the garage, and neighboring homes are visible in a suburban setting under a clear blue sky.
Home in Guadalupe
4.85 out of 5 average rating, 274 reviews

Beach home near golf, wineries, dunes & Vandenburg

This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

Popular amenities for Guadalupe vacation rentals