House vacation rentals in Santee
Find and book unique houses on Airbnb
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santee house rentals
House rentals with a pool
Home in Alpine
4.99 out of 5 average rating, 118 reviewsRancho Maderas Lodge- Solar Heated Pool, King Bed
Oct 20 – 27
Home in La Mesa
4.98 out of 5 average rating, 128 reviewsMid-Century Style Family House with Spa
May 31 – Jun 7
Home in San Diego
5.0 out of 5 average rating, 140 reviewsMidcentury Lux 4BR home with Pool, Spa & Cabana
Feb 12 – 19
Home in La Mesa
4.87 out of 5 average rating, 131 reviewsThe Queen House
Nov 23 – 30
Home in La Mesa
4.93 out of 5 average rating, 107 reviewsUpdated TownHome, Great Location, Fantastic Views
Jan 15 – 22
Home in La Mesa
4.81 out of 5 average rating, 134 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
Aug 18 – 25
Home in San Diego
4.87 out of 5 average rating, 143 reviewsBright and spacious home with views, pool & spa.
Aug 18 – 25
Home in San Diego
4.97 out of 5 average rating, 181 reviewsKids Paradise LUXURY RESORT POOL AC PLAYSET/TOYS
Sep 27 – Oct 4
Weekly house rentals
Home in San Diego
4.98 out of 5 average rating, 281 reviewsPenny's Place: Modern Oasis w Gorgeous Yard
Home in Lakeside
5.0 out of 5 average rating, 33 reviewsTerra Mesa - Charming Retreat
Nov 19 – 26
Home in Santee
5.0 out of 5 average rating, 4 reviewsSimple and Cozy home. Great for snowbirds.
Sep 11 – 18
Home in El Cajon
4.98 out of 5 average rating, 90 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
Aug 27 – Sep 3
Home in El Cajon
5.0 out of 5 average rating, 7 reviewsCozy 1BR Home with Lovely Front Yard
Dec 22 – 29
Home in Lakeside
5.0 out of 5 average rating, 14 reviewsSleeps 6 Casita - The Morey de Prieto Surf Ranch
Nov 6 – 13
Home in Lakeside
4.88 out of 5 average rating, 52 reviewsAnna’s Happy Place
Oct 19 – 26
Home in La Mesa
4.89 out of 5 average rating, 28 reviewsCasita De Grossmont Pool House
Feb 25 – Mar 4
Private house rentals
Home in Santee
5.0 out of 5 average rating, 11 reviewsHeated Pool, fire pit hot tub, views, Hiking
Oct 19 – 26
Home in El Cajon
5.0 out of 5 average rating, 42 reviewsCharming 1BR Getaway
Oct 12 – 19
Home in La Mesa
5.0 out of 5 average rating, 23 reviewsChic and Modern Luxury Private Guest House
Oct 22 – 29
Home in La Mesa
5.0 out of 5 average rating, 45 reviewsEscape to tranquility: the perfect retreat
Jul 5 – 12
Home in La Mesa
4.97 out of 5 average rating, 35 reviewsGarden Studio (40% long, 15% short term discount!)
Nov 8 – 15
Home in Spring Valley
4.87 out of 5 average rating, 15 reviewsIsabel's Private Studio
Sep 7 – 14
Home in Poway
4.98 out of 5 average rating, 64 reviewsFresh and Bright Private Home 1 bd & full bath
Oct 9 – 16
Home in Lakeside
5.0 out of 5 average rating, 15 reviewsLakeside Hilltop Retreat
Nov 12 – 19
Quick stats about house rentals in Santee
Total rentals
50 properties
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Rentals with a pool
20 properties have a pool
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
20 properties are a good fit for families
Total number of reviews
880 reviews
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