
Guesthouse vacation rentals in Santa Cruz de la Sierra
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Santa Cruz de la Sierra
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Cozy family home in Santa Cruz de la Sierra
Family house of 320 square meters, on the second floor, with all the utensils and home clothes, wonderful views from its 30 meters of terrace. Ideal for families who want to have a quiet stay of any duration in the City of Santa Cruz de la Sierra. Very well connected with several bus lines that take you to the entire city and surroundings and very close to the Santuario de Cotoca. Nearby has all kinds of services, breakfasts, meals, markets, shops, etc.

Horizontal duplex in backyard of house with pool
Enjoy a horizontal duplex (complete) in the backyard of my house. With its own entrance to the duplex, it shares entrance to the property. Located in a safe and quiet area easily accessible, close to shops, markets, supermarkets, pharmacy, public transportation (blocks from the main avenues), by car 10 min. from the center, 5 min. from the Fexpo, 30 to 40 min. from the airport, 1 block walk from the society of engineers SIB, clinic Montalvo and Urbari.

COTTAGE SURROUNDED BY NATURE
It is the second cabin on our land. It was an old house house, which we completely expanded and refurbished. You'll be independent of us in a totally safe environment. You also have other amenities, such as lavaropas, the pool and the aromatic herb garden. Obviously it has wifi (fiber internet) and TV. All windows have mosquito mesh, so these insolent bugs don't disturb your sleep.

Room in the center, two minutes away from everything!
Experience staying in the heart of Santa Cruz, just 3 blocks from the main square. Our bright and cozy room awaits you in a safe and lively area: museums, cafes, bars, shops, and historical spots are just a few steps away. Ideal for those looking for comfort, style and an unbeatable location. With WiFi, details designed for your rest and attention that will make you feel at home.

Spacious house with a patio and parking
Guest house, with a large patio and grill (churrasquera), in a very quiet area. Air conditioning in all environments, thermotanque (hot water), spacious living room. Suite with private bathroom. Common bathroom, sofa bed and spacious sofa on the ground floor. (Can sleep comfortably up to 4 people) Address: km 8, Barrio 14 de Agosto, Calle 3 Between double guard and 17 ½ and 5 ½

Complete centric apartment with garden and pool
Complete centric apartment with an enormous garden and pool. Private apartment with fully staffed kitchen, private bathroom and a bedroom with a queensized bed. You'll also have access to the big garden and the pool to relax and refresh yourself. By choosing our accommodation, you’re also supporting Ñañope, a local NGO dedicated to empowering household workers in Santa Cruz.

Double or Full Room in Downtown
New and elegant building located just 2 blocks from the main square, surrounded by shopping malls, restaurants, cafes, jewelry, perfumerias, perfumerias, it is located a couple of blocks from the house of culture, the cathedral, museums, 1 block, banks, 7 street market and various shops and locals.

room #4 with private bathroom
Enjoy the simplicity of this quiet and centrally located place. 5 blocks from the monument "El Cristo" and five minutes from the city center. 50 meters from the main avenue Cristo Redentor, where multiple transport lines pass.

Private Apartment In Downtown
Welcome to our cozy guest house in one of the most beautiful and safe areas of the center! Just 6 blocks from Plaza 24 de Septiembre, our historic neighborhood offers you a unique experience.

Casa Portal Holístico # 1
Enjoy this mystical space of tranquility and harmony where your nights will be restored and revitalizing with the energy of the Holistic Portal

department to share TamisaIII
Disfruta de la sencillez de este alojamiento tranquilo y céntrico.

Apartment-style room
Disconnect from your concerns in this spacious and serene space.
Popular amenities for Santa Cruz de la Sierra guesthouse rentals
Family-friendly guest house rentals

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

New independent house 5 rooms

Cozy family home in Santa Cruz de la Sierra

COTTAGE SURROUNDED BY NATURE
Guest house rentals with a patio

Room #7 with a private bathroom.

El Peregrino 2 Inn

Mirador del Cielo - Boutique Apart Hotel 2

El Peregrino 3 Inn

Room #6 with private bathroom

family home to share

El Peregrino 4 Inn

Bedroom #2 with a private bathroom.
Other guesthouse vacation rentals

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

New independent house 5 rooms

Cozy family home in Santa Cruz de la Sierra

COTTAGE SURROUNDED BY NATURE
Quick stats about guesthouse rentals in Santa Cruz de la Sierra

Total vacation rentals
Explore 50 vacation rentals in Santa Cruz de la Sierra

Nightly prices starting at
Santa Cruz de la Sierra vacation rentals start at € 9 per night before taxes and fees

Verified guest reviews
Over 350 verified reviews to help you choose

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Santa Cruz de la Sierra vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals
Destinations to explore
- Cochabamba Vacation rentals
- Sucre Vacation rentals
- Tarija Vacation rentals
- Oruro Vacation rentals
- Samaipata Vacation rentals
- Uyuni Vacation rentals
- Potosí Vacation rentals
- Trinidad Vacation rentals
- Buena Vista Vacation rentals
- Villa Tunari Municipality Vacation rentals
- Colinas del Urubó Vacation rentals
- Roboré Vacation rentals
- Rentals with breakfast Santa Cruz de la Sierra
- Hotel rooms Santa Cruz de la Sierra
- Family-friendly rentals Santa Cruz de la Sierra
- Loft rentals Santa Cruz de la Sierra
- Rentals with a sauna Santa Cruz de la Sierra
- Rentals with an EV charger Santa Cruz de la Sierra
- Cottage rentals Santa Cruz de la Sierra
- House rentals Santa Cruz de la Sierra
- Rentals with a fireplace Santa Cruz de la Sierra
- Rentals with beach access Santa Cruz de la Sierra
- Fitness-friendly rentals Santa Cruz de la Sierra
- Rentals with a hot tub Santa Cruz de la Sierra
- Pet-friendly rentals Santa Cruz de la Sierra
- Rentals with lake access Santa Cruz de la Sierra
- Condo rentals Santa Cruz de la Sierra
- Beachfront rentals Santa Cruz de la Sierra
- Serviced apartment rentals Santa Cruz de la Sierra
- Rentals with a patio Santa Cruz de la Sierra
- Rentals with a home theater Santa Cruz de la Sierra
- Rentals with pools Santa Cruz de la Sierra
- Apartment rentals Santa Cruz de la Sierra
- Villa rentals Santa Cruz de la Sierra
- Smoking-friendly rentals Santa Cruz de la Sierra
- Rentals with a washer and dryer Santa Cruz de la Sierra
- Rentals with outdoor seating Santa Cruz de la Sierra
- Rentals with a fire pit Santa Cruz de la Sierra
- Guesthouse rentals Santa Cruz
- Guesthouse rentals Bolivia




