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Vacation rentals in Santa Cruz de la Sierra

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
An infinity pool reflects the city skyline, featuring sleek high-rise buildings in the background. The pool's calm waters create a serene environment, while green foliage frames the area, enhancing the visual appeal of this outdoor space.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Movie view, spacious, Tina, balcony and garage

Upon entering, you appreciate the elegance and style of decoration, high ceilings that provide a feeling of spaciousness and luminosity. The living room is spacious and comfortable, with a luxury built-in kitchen that adds a touch of warmth and elegance. Social areas to impress, with designer and high quality furniture. Churrasquera and a wonderful infinity pool. But what really stands out about this apartment is the breathtaking view that is enjoyed from the terrace or the balcony.

Guest favorite
A modern condominium building is situated at the corner of a quiet street, featuring multiple floors with large balconies. Green landscaping surrounds the property, and a clear blue sky provides a bright backdrop, highlighting the building’s contemporary architecture.
Loft in Santa Cruz de la Sierra
4.91 out of 5 average rating, 178 reviews

Modern Studio Apartment near Zoo - Fast WiFi

Bienvenido a tu hogar en Santa Cruz! Disfrutá un monoambiente moderno, seguro y totalmente equipado, a pasos del Zoológico. Ideal para parejas, ejecutivos o nómadas digitales. Ofrecemos Internet de alta velocidad, estación de trabajo, cocina equipada y atención personalizada para una estadía inolvidable. Ubicación estratégica en zona tranquila, con self check-in y WiFi rápido. Totalmente equipado y perfecto para largas estadías, garantizando tu confort y seguridad. Te esperamos!

Guest favorite
Condo
5 out of 5 average rating, 5 reviews

The Jewel of Equipetrol

Welcome to our 2 bedroom 3 bathrooms apartment, recently renovated, located in the heart of Equipetrol in the new Sky Condominium. The flat offers two spacious rooms, one of which can be used as an office. Each room has its own bathroom, and there's additionally a guest toilet. Moreover, an elegant American kitchen welcomes you to the home. The bright living room receives a lot of natural light and has a Smart-TV. The flat has two balconies with a beautiful view to the city.

Top guest favorite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 25 reviews

Green Tower - 26th Floor Spectacular Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a pool, steam sauna, spectacular views from the 26th floor to the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 8 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy top-notch cuisine in the same building, in Jardines de Asia, Caudilla, and the impressive Sky bar, as well as free access to the pool, sauna, barbecues and the Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Top guest favorite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 42 reviews

Modern Apt WiFi, AC, Kitchen, Pool, Washer, Parkng

✨ A space designed for your comfort and relaxation. Located in a safe and quiet area, this modern apartment combines style, convenience, and technology to offer you a unique experience. Perfect for business travelers, couples, or small families, this accommodation features high-speed WiFi, air conditioning, and premium entertainment, along with access to a pool, gym, and free parking. 📌 Enjoy an unforgettable stay with all the amenities you deserve!

Top guest favorite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 34 reviews

Elegante departamento familiar en Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Guest favorite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Condo in Santa Cruz de la Sierra
4.88 out of 5 average rating, 224 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favorite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 108 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favorite
A compact living area features a dark blue sofa facing a flat-screen TV mounted on the wall. A modern dining table with two chairs is positioned near the kitchen, which includes sleek cabinetry and stainless steel appliances. Natural light brightens the space through a large window.
Apartment in Santa Cruz de la Sierra
4.9 out of 5 average rating, 105 reviews

Hermoso Apartamento 1 dormitorio Equipe

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Top guest favorite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 123 reviews

Comfortable and modern studio - beautiful view

Bienvenidos a la zona más activa de Santa Cruz! El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi y tv cable con canales nacionales y extranjeros y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Top guest favorite
A large rooftop pool is framed by vibrant greenery, reflecting the clear blue sky and surrounding skyline. Modern buildings can be seen in the distance, providing a sense of the urban environment while inviting relaxation and leisure.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

Modern Studio | Prime Location

Modern and comfortable studio in the heart of Equipetrol, steps from top cafes, restaurants, and a major shopping mall. The building offers a large pool, fully equipped gym, steam and dry sauna, and a game room with pool and foosball tables. Ideal for business or leisure stays in a vibrant and secure area of Santa Cruz.

Popular amenities for Santa Cruz de la Sierra vacation rentals

Quick stats about vacation rentals in Santa Cruz de la Sierra

  • Total rentals

    4.5K properties

  • Nightly prices starting at

    € 9 before taxes and fees

  • Total number of reviews

    52K reviews

  • Family-friendly rentals

    1.3K properties are a good fit for families

  • Pet-friendly rentals

    1.2K properties allow pets

  • Rentals with a pool

    3.1K properties have a pool

Frequently Asked Questions

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has a tropical savanna climate. During the wet season from November to March, temperatures range from 68°F to 86°F (20°C to 30°C). In the dry season from April to October, temperatures vary between 59°F and 79°F (15°C to 26°C).

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Visitors often explore the Guembe Biocenter, stroll around Plaza 24 de Septiembre, shop at La Recova Market, or take a tour of the Cathedral of Santa Cruz. Outdoor enthusiasts frequently choose to visit the Santa Cruz Zoo or the Botanical Gardens.

  • What is the best time of year to visit Santa Cruz de la Sierra?

    The most frequented time to visit Santa Cruz de la Sierra is during the dry season from April to October. The International Baroque Music Festival in April and the Santa Cruz Carnival in February are popular local events.

  • What are the best places to stay in Santa Cruz de la Sierra?

    Many visitors choose to stay in areas such as Equipetrol, a modern, upscale neighborhood, or the city center with its colonial architecture and vibrant markets. For a quieter stay, Urubó is a residential area with lush green spaces.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Visitors often explore the Metropolitan Cathedral, the Noel Kempff Mercado Museum, and the Artecampo Gallery. The Jardín de las Delicias water park and the Arenal Park are also frequently suggested spots.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Although Santa Cruz de la Sierra is largely flat, the Amboró National Park, about a two-hour drive from the city, has numerous hiking trails through diverse ecosystems, including rainforest and cloud forest.

  • What are some family activities to do in Santa Cruz de la Sierra?

    Families usually enjoy a day at the Guembe Biocenter with its butterfly house and orchidarium, exploring the Santa Cruz Zoo, or picnicking at the Lomas de Arena Regional Park. A visit to the Interactive Science Museum can also be fun for kids.

  • What are some of the best day trip ideas in Santa Cruz de la Sierra?

    Popular day trips from Santa Cruz de la Sierra include exploring the diverse flora and fauna at Amboró National Park, visiting the Jesuit Missions of Chiquitos, or discovering the sand dunes at Lomas de Arena Regional Park.

  • How much does it cost to stay in tiny house rentals in Santa Cruz de la Sierra?

    Experience the best of Santa Cruz de la Sierra with our tiny house rentals, starting at about $10 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there Santa Cruz de la Sierra condo rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 530 condo rentals with pools in Santa Cruz de la Sierra, available on Airbnb. Make a splash and soak up the sun in style!

Destinations to explore