
Vacation rentals in Santa Cruz County
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Top-rated vacation rentals in Santa Cruz County
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
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Popular amenities for Santa Cruz County vacation rentals
Other great vacation rentals in Santa Cruz County
Guest favorite

Home in Tubac
4.93 out of 5 average rating, 29 reviewsTubac private getaway!
Guest favorite

Condo in Tubac
5 out of 5 average rating, 68 reviewsLovely two bedroom condo- Pool, spa, and gym.
Top guest favorite

Guesthouse in Patagonia
4.99 out of 5 average rating, 73 reviewsDream House
Guest favorite

Home in Tubac
4.96 out of 5 average rating, 25 reviewsStylish Townhome, 2BD, 2BA-Pool & Gym Access.
Guest favorite

Home in Tubac
5 out of 5 average rating, 9 reviewsMesquite Haven
Top guest favorite

Guesthouse in Patagonia
4.98 out of 5 average rating, 97 reviewsUniquely charming The Casita. Heart of Patagonia.
Top guest favorite

Guesthouse in Sonoita
4.98 out of 5 average rating, 59 reviewsKitty Casita
Top guest favorite

Home in Arivaca
5 out of 5 average rating, 16 reviewsTres Bellotas Cowboy House
Destinations to explore
- Rentals with a fireplace Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- House rentals Santa Cruz County
- Apartment rentals Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- Rentals with a washer and dryer Santa Cruz County
- Rentals with a patio Santa Cruz County
- Rentals with pools Santa Cruz County
- Rentals with a fire pit Santa Cruz County
- Kartchner Caverns State Park
- Reid Park Zoo
- Patagonia Lake State Park
- Tucson Botanical Gardens
- Arizona-Sonora Desert Museum
- Titan Missile Museum
- Tombstone Courthouse State Historic Park
- Mission San Xavier del Bac
- Tumamoc Hill
- Sonoita Vineyards
- Arizona Hops and Vines
- Callaghan Vineyards
- Charron Vineyards
- Rune Wines