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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 32 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Top guest favorite
Home in Yuma
5 out of 5 average rating, 160 reviews

Desert Escape Heated Pool/2king beds/ Toy parking

Year-Round Comfort and Relaxation in Yuma Escape the summer heat or bask in the warm winter sun in this private, tranquil retreat. This spacious home offers everything you need to unwind and enjoy your time in Yuma. 2 king beds & 2.5 baths there is plenty of space. Conveniently located close to I-8 shopping, dining, and fuel. Whether you are looking to relax in the sun, cool off in the pool, or enjoy time with family and friends, this is the perfect place to make the most of your stay in Yuma.

Guest favorite
Apartment in San Luis
4.96 out of 5 average rating, 141 reviews

Heated Pool, 2 Queen beds private apartment Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Top guest favorite
A private outdoor space showcases a wood gate framed by lush greenery, including climbing vines and shrubs. The ground is paved, and seating is arranged nearby, offering a place to relax. The area is well-maintained, providing a serene environment.
Home in Yuma
4.98 out of 5 average rating, 235 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Guest favorite
Tiny home in Yuma
4.87 out of 5 average rating, 159 reviews

Santa Fe 4 Tiny Studio

Welcome to Casa Santa Fe #4! "This boutique hotel-themed house" offers everything from single to double rooms. Santa Fe #4 is a cosy one-room studio that's fully equipped for a wonderful stay. Our fantastic communal pool area is all set for enjoyment! Just a quick note, if you fancy a dip in the jacuzzi, it does come with an extra fee of $40 USD. We've tailored everything here to provide you with a serene and peaceful stay. We're so excited for your visit!

Top guest favorite
Home in San Luis Río Colorado
4.97 out of 5 average rating, 114 reviews

Casa Victoria, It's a pleasure to welcome you

Enjoy comfort, privacy, and a prime central location at Casa Victoria. A modern 2-story home (2 years old), perfect for families, couples, travelers, and pets. Sleeps up to 6 guests in a quiet, safe neighborhood—ideal for relaxing or exploring the city. Amenities: 🏡 2-story private home 🛏️Sleeps 6 guests 🚗 Covered parking for 2 cars 🔥 Gas BBQ grill ☕ Coffee station 🌅 Balcony 🐾 Pet-friendly 📍 Central location 🔒 Safe & peaceful area

Top guest favorite
Apartment in Yuma
4.96 out of 5 average rating, 133 reviews

Peaceful Yuma Stay

Welcome to your peaceful stay at Yuma 1 bed Apt. A charming apartment to fit comfortably up to 4 people. Perfect for short or long stays. Enjoy lazy afternoons in the shared pool and backyard. Located in a quiet, peaceful and safe neighborhood. Pool is not heated but is available all year. This apartment is adjacent to another airbnb property. Complete apartment is 100% private.Access to shared pool and backyard

Guest favorite
Home in Yuma
4.94 out of 5 average rating, 405 reviews

LUXURY Living!

You will enjoy your stay at this fully furnished LUXURY rental. It has 4 bedrooms, 2 bathrooms and is located on a quiet cul-de-sac. Relax on the large covered patio, next to the pool, or by fire pit. Great location in the center of town near the hospital, golf courses, shopping, and restaurants. You are just a short drive away from Mexico, Colorado River, sand dunes, and hiking.

Top guest favorite
A cozy sleeping area features a spacious bed with soft gray bedding and multiple plush pillows. A decorative wall map is displayed above the headboard, and a bedside lamp provides soft lighting. A small plant and a framed picture add subtle touches to the room.
Apartment in San Luis Río Colorado
4.97 out of 5 average rating, 100 reviews

Comfortable SLRC Apartment

Keep it simple at this peaceful and centrally-located place. Located in the geographic center of San Luis Rio Colorado, very close to the main shops, schools, and workplaces. 10 minutes from the international border crossing. This apartment is attached to a single-family house but has a separate entrance, private bathroom and a parking space in a closed garage.

Guest favorite
A single-story house features a light-colored exterior and a dark wooden front door. Two windows are positioned symmetrically on either side of the entrance. A stone pathway leads up to the door, surrounded by gravel and bordered by a wooden fence.
Guesthouse in San Luis
5 out of 5 average rating, 47 reviews

Warm & Modern | Casa Luna w/ Patio & Kitchen

Welcome to Casa Luna! Casa Luna is your cozy and peaceful retreat ✨ A spacious bedroom, private bathroom, fully equipped kitchen, and comfy living room all in one open, inviting space ☕️🛏️ Whether you’re here to relax or explore, you’ll have everything you need for a comfortable and memorable stay. We can’t wait to welcome you! ❤️🏡

Superhost
Guesthouse in Somerton
4.78 out of 5 average rating, 319 reviews

Full Studio In a Ranch

Enjoy your stay in a quiet and peaceful Studio in the Counties/outskirts of Yuma and Somerton . You will see my Rottweiler Dog in the backyard as well listen to the roosters sing in the morning. You can walk around the block peacefully. Enjoy your fully fenced private yard area

Guest favorite
Home in San Luis
4.7 out of 5 average rating, 10 reviews

Desert Escape-Minutes From MX Border

Welcome to Desert Escape! Enjoy a quiet and relaxing stay in the heart of San Luis. Whether you’re visiting for work or leisure, this comfortable retreat is close to everything while giving you the peace and quiet you deserve 🌵

Popular amenities for San Luis vacation rentals

When is the best time to visit San Luis?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in San Luis?

    San Luis has more than 120 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in San Luis?

    Experience the best of San Luis with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis?

    Four-legged friends are welcome in San Luis. Choose from more than 70 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in San Luis?

    Yes! Work meets play with ease at over 90 vacation rentals in San Luis featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there San Luis vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 vacation homes with pools in San Luis, available on Airbnb. Make a splash and soak up the sun in style!

  • Where should I stay in San Luis?

    Make yourself at home in San Luis by choosing from our most frequently booked neighborhoods. We have over 190 vacation rentals in Comercial, over 190 vacation rentals in Frontera Estates, and over 190 vacation rentals in Parque Industrial.

  • Do house rentals in San Luis have air conditioning?

    Absolutely! We offer over 100 house rentals with air conditioning in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have a kitchen?

    Absolutely! We offer over 100 house rentals with a kitchen in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have wifi?

    Absolutely! We offer over 100 house rentals with wifi in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have free parking?

    Absolutely! We offer over 100 house rentals with free parking in San Luis. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in San Luis

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis

  • Verified guest reviews

    Over 4,870 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 70 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

  1. Airbnb
  2. United States
  3. Arizona
  4. Yuma County
  5. San Luis