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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy outdoor patio is furnished with a table and chairs, creating a relaxed dining space. The wall features decorative planters. In the background, the shared pool is visible, adding a refreshing element to the serene atmosphere.
Guesthouse in Yuma
4.94 out of 5 average rating, 108 reviews

Relaxing 2 Bedroom Attached Guest House

Stylish and relaxing attached 2Bedroom Guest house.Quiet neighborhood 5 min away from Onvida Yuma Regional center 4 min from Walmart,Starbucks and fast food restaurants. You will also have access to the shared pool and backyard.Pool is not heated but is available all year.Fully stocked kitchen,stacked washer & dryer in unit for your convenience.This apartment is adjacent to another airbnb property.Complete apartment is 100% private.Access to shared pool and backyard. Max guest occupancy 4 people

Guest favorite
A contemporary home features a warm wooden front door, complimented by stone accents. A well-maintained lawn with tiered landscaping leads up to the entrance. Large windows allow natural light to illuminate the interior, while a two-car garage is visible on one side.
Home in San Luis
5 out of 5 average rating, 33 reviews

Mi Bonita Coquette

This new home is welcoming the minute you walk in. Our home offers the opportunity for short or long term stays with all the essentials to make you feel right at home. The home offers a cozy environment in which you will be able to enjoy outdoor grilling and it is perfect for enjoying your favorite wine at the outdoor bar. Half bathroom at the backyard. This home is only 20 minutes away from Yuma, AZ. and 5 minutes away from our neighboring country, Mexico. Free parking space for 2- 3 cars.

Superhost
A modern single-story home features a light exterior with stone accents. A two-car garage is visible, accompanied by a neatly landscaped front yard with green grass and desert shrubs. The property is surrounded by a low wall, offering a sense of privacy.
Home in San Luis
4.83 out of 5 average rating, 18 reviews

Desert Oasis Minutes From MX Border

Relax with the whole family at this peaceful place to stay. Only minutes away from the US/Mexico border! Our home is located in a new construction neighborhood. Modernly decorated and cozy feel all throughout. Full access to 2 car garage, spacious rear patio and full kitchen. Nearby attractions include MX for some day shopping or tacos, Waylon's Water World, West Wetlands Park, Cocopah R.C Golf Course & Casino and let's not forget, many off roading areas if you want to bring off roading toys!

Guest favorite
Apartment in San Luis
4.96 out of 5 average rating, 141 reviews

Heated Pool, 2 Queen beds private apartment Enjoy

The property is divided in to two airbnbs with there own private entrence and private backyard grill outdoor dining and fire pit lounge area. None of the areas are shared they are 100% privateEnjoy your time at this stylish place make great memories at the poolside !! Pool is totally private for this unit in winter season pool temperature can vary depending on the weather outside it’s not a close pool heater is normally on from Nov to May. Enjoy your time in this special place.

Top guest favorite
A private outdoor space showcases a wood gate framed by lush greenery, including climbing vines and shrubs. The ground is paved, and seating is arranged nearby, offering a place to relax. The area is well-maintained, providing a serene environment.
Home in Yuma
4.98 out of 5 average rating, 237 reviews

Tuscany Style Casita

Discover a newly remodeled Tuscany-style casita that feels like a quiet Italian escape in the heart of Yuma. Thoughtfully furnished for up to four guests. This two bedroom casita is truly cozy and warm. The neighborhood is safe, quiet and well kept. We are centrally located with Onvida hospital 5 min away, 10 min to the airport, 10 min to Yuma Palms and downtown and just minutes from Sprouts, Starbucks, Bubba's 33, local restaurants and more. We offer gated private parking.

Top guest favorite
Place to stay in Yuma
4.92 out of 5 average rating, 182 reviews

Santa Fe #2 | Charming Guest Suite in Yuma

Welcome to Casa Santa Fe 🌿 — four unique apartments with one or two bedrooms, each featuring a private kitchenette 🍳, dining area 🍽️, and private terrace or patio. Designed for a serene and peaceful stay. ✨ Enjoy our stunning pool area featuring a pool bar 🍹, sunbeds ☀️, and grill 🔥 — perfect for relaxing and soaking up Yuma's beautiful weather. 🎖️ Military discount + one free night on 30-day stays. Thank you for your service! 💰 Extended stay discounts available!

Superhost
The exterior of the house is displayed, featuring a textured tile roof and light-colored walls. A spacious driveway leads to a closed garage, while neatly arranged palm trees and manicured grass flank the pathway, creating an inviting entrance.
Home in San Luis
4.87 out of 5 average rating, 68 reviews

Spacious house with a modern kitchen + 4 bedrooms

This Beautiful house is perfect to bring family , friends or for a couple . This house offers you comfort and is secure , with a spacious patio to relax and enjoy the outdoors . There's an emergency medical center just around the corner . Pleasant area to walk in the morning or just enjoy a delicious barbecue in the afternoon on the patio . It's a 10-minute drive to the Border Crossing and 5-minute drive to a supermarket , restaurants and gyms .

Guest favorite
A refreshing pool is surrounded by a spacious backyard, featuring a shaded seating area with comfortable blue furniture. String lights are overhead, and a small palm tree adds greenery. The yard is enclosed by a low wall, offering privacy.
Home in Yuma
4.88 out of 5 average rating, 40 reviews

Guest-Favorite 3-Bedroom charming Home with Pool

Bring the whole family/friends/coworkers to this great home with lots of room for fun or a nice warm stay, or even if you would like to be in one of the most secure and family friendly areas of town, also all your shopping needs, beauty salon, food variety & a gym is just a mile away & close to the interstate access. We are excited to have you in our beautiful home, for you to enjoy the space and make endless memories....

Guest favorite
Camper/RV in San Luis Río Colorado
4.89 out of 5 average rating, 135 reviews

Alebrije: Full of Life, Nature, and Color

Welcome to this place created especially for you. Enjoy a morning coffee in a space full of nature and tranquility. Our motorhome has all the amenities and you'll enjoy a pleasant rest. You can also enjoy a barbecue with your family while the warmth of the campfire lights up your evening. Alebrije has privacy as it is located on a fenced plot of land exclusively for the motorhome and an excellent neighborhood.

Top guest favorite
Apartment in San Luis Río Colorado
4.97 out of 5 average rating, 100 reviews

Comfortable SLRC Apartment

Keep it simple at this peaceful and centrally-located place. Located in the geographic center of San Luis Rio Colorado, very close to the main shops, schools, and workplaces. 10 minutes from the international border crossing. This apartment is attached to a single-family house but has a separate entrance, private bathroom and a parking space in a closed garage.

Guest favorite
A fully equipped kitchen is shown, featuring wooden cabinets, a refrigerator, and a gas stove. A microwave sits on the counter, along with a coffee maker. A dining table, with decorative placemats, offers seating for multiple guests.
Home in San Luis
4.94 out of 5 average rating, 52 reviews

Retro vacation house.

This Retro House is located in the heart of San luis Az, easy access to everything. Right across Walmart, Dollar tree, Carls JR, Starbucks, etc. Less than 5 mins from the San Luis Rio Colorado border. 20 min from Yuma & 10 mins from Somerton. Our place is perfect to host comfortably up to 6 people. Short and long stays are welcome.

Guest favorite
Home in San Luis Río Colorado
4.92 out of 5 average rating, 13 reviews

Casa Topaz, ideal for your stay, comfortable, safe

Enjoy the comfort of this quiet and centrally located accommodation. With an electric garage for your vehicle, and everything you need for a pleasant stay, we have a water pressure pump for uninterrupted bathing, an electric water heater that provides hot water quickly, as well as air conditioning and heating.

Popular amenities for San Luis vacation rentals

When is the best time to visit San Luis?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in San Luis?

    San Luis has more than 120 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in San Luis?

    Experience the best of San Luis with our house rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in San Luis?

    Four-legged friends are welcome in San Luis. Choose from more than 70 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in San Luis?

    Yes! Work meets play with ease at over 90 vacation rentals in San Luis featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there San Luis vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 vacation homes with pools in San Luis, available on Airbnb. Make a splash and soak up the sun in style!

  • Where should I stay in San Luis?

    Make yourself at home in San Luis by choosing from our most frequently booked neighborhoods. We have over 190 vacation rentals in Comercial, over 190 vacation rentals in Frontera Estates, and over 190 vacation rentals in Parque Industrial.

  • Do apartment rentals in San Luis have air conditioning?

    Absolutely! We offer over 40 apartment rentals with air conditioning in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have a kitchen?

    Absolutely! We offer over 100 house rentals with a kitchen in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have wifi?

    Absolutely! We offer over 100 house rentals with wifi in San Luis. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in San Luis have free parking?

    Absolutely! We offer over 100 house rentals with free parking in San Luis. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in San Luis

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis

  • Verified guest reviews

    Over 4,870 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 70 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis rentals

  • 4.8 Average rating

    San Luis stays are highly rated by guests—averaging 4.8 out of 5!

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