Apartment vacation rentals in Saint Charles

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Top-rated apartment rentals in Saint Charles

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The living area features a comfortable leather sofa with colorful accent pillows, set in front of a wooden coffee table. Natural light floods in through two large windows, illuminating the hardwood floor and a decorative rug. A television is mounted on the wall above a cabinet with plants.
Apartment in Maryland Heights
4.87 out of 5 average rating, 176 reviews

Stunning Modern Apt| Kingbed -5 min CreveCoeurLake

Discover your ideal retreat in this newly renovated 2-bedroom apartment, nestled in a charming and cozy building in Maryland Heights. Just moments from Creve Coeur Lake, West Port Plaza, Hollywood Casino & Amphitheater, and the historic charm of St. Charles, this inviting space offers easy access to top dining and entertainment options. Whether you're visiting for a weekend getaway or an extended stay, every detail has been thoughtfully designed to ensure your comfort, relaxation, and enjoyment.

Guest favorite
The living area features a comfortable sofa and a round coffee table, with a decorative plant placed on top. A large Samsung 4K TV displays a Netflix sign on the exposed brick wall. The kitchen is equipped with modern appliances and sleek cabinetry.
Apartment in Soulard
4.89 out of 5 average rating, 311 reviews

The Loft on 11th

This rustic themed modern Soulard home has brand new everything to the studs! Some of many features include: -65in Samsung 4K TV w FREE NETFLIX -Free next door shuttle to all home Cardinals, Blues, STL FC and Battlehawk games -Walk to Dukes sports bar, McGurks patio, Mollys night club, Chavas mexican, Goshen coffee, Hammerstones brunch, Famers Market, etc. -Walk in shower w custom tile, massive shower head + relaxing seat -Professionally designed -Fully equipped kitchen -In unit washer/ dryer

Guest favorite
A spacious living area features hardwood flooring and a cozy fireplace. A comfortable sofa and wooden coffee table are positioned near a rustic accent wall. The open kitchen is visible in the background, and large artwork depicting wildlife enhances the decor.
Apartment in Soulard
4.95 out of 5 average rating, 111 reviews

Soulard Lodge• Queen Bed • WiFi • Laundry • Patio

Rustic Retreat in Soulard – Walk to Bars & Farmers Market! Unwind in this cozy 1-bedroom escape in the heart of Soulard, where rustic charm meets modern comfort. Enjoy a plush Queen bed with premium linens, fiber WiFi (500 Mbps), and a fully stocked kitchen with Keurig. The spacious living area is perfect for relaxing, and the in-unit washer/dryer adds convenience. Just steps from Soulard’s vibrant nightlife, top restaurants, and the historic Farmers Market, with a Walk Score of 90. Book today!

Top guest favorite
A contemporary living area features a gray sofa and an accent chair with a glass coffee table at the center. Natural light filters through numerous windows, illuminating the space. A dining area is visible in the background, complete with a wooden table and stylish chairs.
Apartment in Central West End
4.83 out of 5 average rating, 219 reviews

Gorgeous condo in HEART of STL! Gourmet kitchen✨

This St. Louis Retreat has everything you need in a PRIME location! Enjoy shops, casual & fine dining, and more right outside your door. Just minutes away is Forest Park, public transportation, major hospitals, Saint Louis Zoo, & Washington University. ✨ All new designer finishes 🏨 Sleeps 4 with Queen bed and sleeper sofa 🌅 Lots of sunlight throughout 🏫 Desk/workspace ☕ Coffee maker 👕 Washer/Dryer in unit 📶 Wifi 📣 Secured entry with video-monitor intercom 🍝🍹Walk to restaurants & shops

Top guest favorite
A charming dining area is highlighted by a glass-top table surrounded by wooden chairs. A window with decorative glass provides natural light, framing a view of greenery outside. The shelves showcase a collection of vintage kitchenware and decorative roosters.
Apartment in Southwest Garden
4.92 out of 5 average rating, 648 reviews

Historic, great area, French country comfort

First, check out all 4 of our private 5 Star listings that creatively combines the old with the new. If one is unavailable, check the others by going to “My Profile” and scrolling down until you see all 4. This Historic building; built in 1896 has changed missions through the years; From church, to merc. Trade, to grocery store; quite the history have graced these walls. You’ll love our safe, Southwest Gardens area; next to the famous “Hill” offers unmatched restaurant, shops, bakeries.

Top guest favorite
A modern kitchen area features white cabinetry and a kitchen island with three cushioned stools. Pendant lights hang above the island, illuminating the space. A doorway leads to another room, with a glimpse of additional kitchen appliances visible in the background.
Apartment in St. Charles Historic District
4.94 out of 5 average rating, 388 reviews

Christmas Getaway in Historic Old St. Charles

Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.

Top guest favorite
A view from the living area into the bedroom, showcasing a serene space with a queen-size bed dressed in crisp white linens and accented by earthy throw pillows. Natural light illuminates the room, complemented by a ceiling fan and light-toned wooden flooring.
Apartment in North Hampton
4.99 out of 5 average rating, 185 reviews

The Zen Den - Centrally Located, Calm and Tranquil

The Zen Den was conceptualized out of a desire to create a calm and peaceful oasis centrally located in the North Hampton neighborhood of St. Louis where parks, cafés, restaurants, and entertainment are only minutes away. The space features modern appliances, contrasted with soft light features and natural building materials, such as reclaimed lumber, to convey a sense of calm and tranquility. Ideal for those guests seeking to retreat at the end of a busy day exploring or remote working.

Guest favorite
A light and airy living room is highlighted by a cozy white sofa adorned with various beige and cream throw pillows. A small side table holds a decorative tray with a plant and a soft throw blanket is draped over the arm of the sofa. Natural light enters through a nearby window.
Apartment in St. Louis
4.93 out of 5 average rating, 117 reviews

Charming Kirkwood (2) Bedroom

Welcome to this cozy home-away-from-home, designed with the Airbnb guest in mind! Minutes from downtown Kirkwood and 20 minutes from downtown STL it is perfect for those traveling for work or fun! Guests are provided internet, hotel linens, & laundry access. Settle in & enjoy cooking in the kitchen, relaxing in the living room, and resting in your hotel-inspired bedrooms. This listing was converted from a shared apartment to a full unit in August 2024. Prior reviews are for one bedroom.

Top guest favorite
A cozy living area features grey walls and stylish furnishings, including a dark leather sofa and a matching armchair. A geometric area rug adds subtle color underfoot. Natural light shines through the window, and a piece of wall art adds character to the space.
Apartment in Benton Park Historic
4.97 out of 5 average rating, 239 reviews

Cozy 1BR Apartment the "Ferner Flatette"

This unique, minimalistic apartment is located in the historic Benton Park neighborhood. A stroll away from restaurants, coffee shops, antique row and the park complete with lakes and walking paths. Recently renovated, its just minutes from downtown attractions: the Gateway Arch, Busch Stadium, Enterprise Center and Union Station Aquarium. Strict capacity of 2 persons. Window unit A/C, central heat. No pets, no smoking, no local guests. Government issued photo ID required prior to checkin.

Top guest favorite
A bright sleeping area features a spacious bed positioned against a soft blue wall. Two bedside tables with lamps flank the bed. A round mirror hangs above a small armchair in the corner, while a patterned area rug adds warmth to the wooden floor.
Apartment in North Hampton
4.94 out of 5 average rating, 101 reviews

Fresh Studio in North Hampton Neighborhood

Come solo or with a friend or partner and enjoy a stylish experience at this freshly renovated and centrally-located place. Quiet space within 15 minutes of the St. Louis Arch, Cardinals baseball, Blues hockey, and the night life of Downtown, Soulard, and The Hill to name a few. Perks: Free parking, high speed internet, queen size bed, coffee, and more. Thanks in advance for funding my addiction to the many flavors of gooey butter cake from Russell’s Cafe and Bakery.

Guest favorite
A modern kitchen area features light wood cabinetry and black appliances. Two upholstered stools are positioned at a counter, with a small desk and chair nearby. Natural light pours in through large windows, illuminating the hardwood floor and creating a bright space.
Apartment in LaSalle Park
4.93 out of 5 average rating, 526 reviews

Cozy One Bedroom Apt on Soulard

SOULARD - is one of the trendiest neighborhoods in STL. Cozy and updated one bedroom apartment is the perfect retreat if your looking to be in the heart of STL, without the cost of downtown w/ free parking! Minutes from Downtown/Busch Stadium & other lively neighborhoods. I have another AIRBNB one bedroom unit in this building so check that out that is a nightly rental. https://www.airbnb.com/rooms/14261370. NO one night LOCALS booking allowed.

Top guest favorite
A comfortable living room features a blue sofa, accompanied by a green chair and a wooden dining table. Natural light enters through a window with patterned drapes, illuminating the neutral walls and a decorative area rug. A wall clock and framed art complete the space.
Apartment in Lindenwood Park
4.88 out of 5 average rating, 221 reviews

Warriors Rest and Repose in St. Louis Hills

This first floor apartment is part of a 4-unit building on Jamieson. It is in St. Louis Hills neighborhood, a community with grocery and retail stores on the main drags – Chippewa and Hampton, with easy reach to city parks and the River Des Peres Greenway Trail. It is well-placed for all city visitors, here for excursions or family get-togethers, medical visits or business travelers, where visitors can rest and repose for another day of fun!

Popular amenities for Saint Charles apartment rentals

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Quick stats about apartment rentals in Saint Charles

  • Total vacation rentals

    Explore 40 vacation rentals in Saint Charles

  • Nightly prices starting at

    Saint Charles vacation rentals start at € 17 per night before taxes and fees

  • Verified guest reviews

    Over 3,030 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Saint Charles vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Saint Charles rentals

  • 4.8 Average rating

    Saint Charles stays are highly rated by guests—averaging 4.8 out of 5!