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Vacation rentals in Depew

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Top-rated vacation rentals in Depew

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Top guest favorite
A living area is displayed, featuring a dark sofa alongside a patterned armchair. A decorative area rug covers the wooden floor. The background shows a kitchen space with bar seating and modern appliances, contributing to a welcoming atmosphere.
Apartment in Cheektowaga
4.95 out of 5 average rating, 240 reviews

Close to Niagara Falls and Airport, Mall nearby

Niagara Falls is only 30minutes away.Very nice neighborhood. 4minutes from Galleria Mall.Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 plus we have a clean pack and play for your little one. Has own keypad entrance. Full sleeper sofa in living room. One bedroom has a queen bed and tv. The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly. Pets can do their business out front. There are dogs that use the back yard.

Top guest favorite
The exterior showcases a charming entrance with large windows and a covered porch. A white wicker chair with colorful cushions is positioned beside a small side table. The surrounding yard features greenery, providing a peaceful outdoor space.
Guest suite in Buffalo
4.99 out of 5 average rating, 346 reviews

Suite Sherry's - Your home away from home!

Come feel at home in this quiet & cheery private suite setting attached to the rear of our home and enjoy the view of park like yard. Quiet residential area located in Erie County! Only 20 Min. to downtown Buffalo, Peace Bridge (Canada), Buffalo Airport and the Galleria Mall. 10 minutes to New Era stadium (Buffalo Bills) or to Harvest Hill Golf Course or Chestnut Ridge park, 15 min to Woodlawn beach, 15 min to Hamburg Fair, 15 min to Basilica & Botanical Gardens, 25 miles to Niagara Falls.

Superhost
A comfortable living area is displayed, featuring a large sectional sofa with decorative cushions and a wooden coffee table. A 50" Smart 4K TV is positioned on a stand, showcasing a scenic landscape. The space is illuminated by natural light from the adjacent kitchen.
Apartment in Depew
4.91 out of 5 average rating, 117 reviews

Fireman's Park View

Book your stay at our homey and welcoming 3 bedroom space, designed for guests to enjoy. We are a short 10 min drive from the Buffalo Airport. There is plenty to do during your stay: downtown Buffalo and Niagara Falls are both a 20 min drive, and our quiet, safe neighborhood is the perfect place to relax for the evening. We suggest taking a walk at Reinstein Woods nature preserve. With a park in the backyard and access to an abundance of restaurants and shops nearby, you will love this space!

Guest favorite
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 417 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Top guest favorite
An open living space features a round wooden dining table set for two, accompanied by a decorative plant. A gray couch is positioned to one side, with soft light illuminating the area. The room connects to the kitchen and a bathroom area is visible in the background.
Guest suite in Buffalo
4.99 out of 5 average rating, 137 reviews

Carriage house 1-bedroom at Glen Falls

Make yourself at home in this clean 1-bedroom upper apartment in the village of Williamsville! Just a short distance from everything, including the Buffalo Airport, some of the best restaurants/pubs WNY has to offer, Niagara Falls, & downtown Buffalo. All basic amenities are provided: 55" Smart-TV, WIFI, full bathroom, full kitchen including a coffee station, stove, refrigerator, and microwave. Private entrance & driveway. Self check-in. Close to I-290 (Exit 7 Main Street)

Guest favorite
A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.
Guest suite in Lancaster
4.96 out of 5 average rating, 193 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

Guest favorite
A welcoming brick exterior of an upstairs apartment is shown, featuring a neatly manicured lawn. A small tree with white bark stands prominently in the front yard, surrounded by decorative stones. The entrance includes steps leading to a door with windows, reflecting natural light.
Apartment in Cheektowaga
4.85 out of 5 average rating, 102 reviews

Upstairs apartment near the airport

Cozy & stylish upstairs apartment in a quiet suburb. Less than three miles from the airport for stress-free travel! Less than one mile from the Walden Galleria Mall, one of the largest in NY state! Less than 10 miles from downtown Buffalo rich in culture, history, art, GREAT food, and night life. 24 miles to Niagara Falls for beautiful hikes and sight seeing. A fun 2 hour road trip to Toronto! Clean & comfortable with everything you need for a short or long-term stay!

Guest favorite
A modern dining area features a round wooden table surrounded by four white chairs. A stylish light fixture hangs above, complemented by green accent walls. The open layout connects to a well-equipped kitchen with white cabinetry and bar seating, illuminated by natural light from surrounding windows.
Apartment in Elmwood Village
4.88 out of 5 average rating, 231 reviews

Five Points Apartment- Upper Unit

Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking. In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls

Top guest favorite
The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.
Guest suite in Lancaster
4.91 out of 5 average rating, 192 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Top guest favorite
A charming exterior view showcases a white picket fence surrounding a well-kept yard. A lush green lawn is framed by flower beds, and a gazebo is visible in the background, complemented by mature trees providing shade.
Apartment in Williamsville
4.94 out of 5 average rating, 154 reviews

Cozy Williamsville apartment at Madison Place

Cozy 1 bedroom 2nd floor apartment Eat in kitchen with countertop height seating 2 Queen size beds (bed & fold out couch) Brand new built in dishwasher & microwave oven All cookware, silverware & kitchen appliances Fully furnished with all linens, towels and starter supply of soaps, shampoos. Ample closet space and storage Whole house water filter Laundry located in basement Off street parking for 2 cars

Guest favorite
A tranquil bedroom is presented with a spacious bed adorned with soft pillows and a light throw. Flanking the bed are two nightstands with lamps. The room features warm wooden floors and walls painted in a calming gray tone, while natural light filters through the window.
Home in Buffalo
4.92 out of 5 average rating, 153 reviews

Bright, Charming, Private Home

This corner-lot Cape Cod is the perfect spot for 1-6+ who are looking for a centrally-located stay in WNY. Our home is five minutes from the airport, 10 minutes to downtown/waterfront, 15 minutes to Highmark Stadium and 20 minutes to Niagara Falls. This space has been renovated over the past two years including an updated kitchen and bathroom, new floors and finished hardwood.

Guest favorite
A cozy corner features a brick fireplace, framed by decorative plants and two lace-covered windows. A small wooden table stands beside the fireplace, adorned with a candle and vintage items. Nearby, a set of folding chairs is positioned next to a framed floral artwork.
Apartment in Buffalo
4.92 out of 5 average rating, 282 reviews

Peaceful, spacious apartment. Non-smoking.

Traditional South Buffalo lower in the Irish Heritage District. NOT suitable for children aged 1-12. NOT pet-friendly. 10 minutes from Canalside, Key Bank Center, Sahlen Field, Harbor Center, Riverworks and downtown. 20 minutes from Highmark Stadium. 30 minutes from Niagara Falls. Stumbling distance from the Buffalo Irish Center.

Popular amenities for Depew vacation rentals

  1. Airbnb
  2. United States
  3. New York
  4. Erie County
  5. Depew