Vacation rentals in Depew

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Top-rated vacation rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A living area is furnished with a light gray sectional sofa adorned with patterned pillows. A dark armchair complements the space, which is brightened by natural light from large windows. A woven basket holds decorative items, and a subtle area rug adds texture to the floor.
Home in Lancaster
4.98 out of 5 average rating, 57 reviews

eye pleaser

Enjoy a stylish experience at this centrally-located home. Many guests come for the Buffalo Bills games. 25 minute ride to Highmark Stadium. 7 minutes from airport. 20 minutes to downtown Buffalo. Walking distance to the village of lancaster. The village offers restaurants, bars, shopping, coffee shop, barber shop etc. around the corner from the home offers a grocery store, liquor store, consumer beverages, and a gym. Enjoy our out door patio with grill, fire pit, as well as covered side patio.

Top guest favorite
A living room is depicted featuring a white brick fireplace as a focal point, with a dark television mounted above. Grey sofas are positioned around a small wooden table, and bright plants add a touch of greenery. A large window allows light to fill the space.
Home in Lancaster
5 out of 5 average rating, 21 reviews

Mid-Century Modern Upper Unit

Experience the small-town charm in this centrally located Village of Lancaster property. Lancaster’s up-and-coming vibrant downtown offers access to local taproom and bodega, ample restaurant choices, and boutique shopping – all within walking distance! Looking for something to do outside the Village? This property is perfectly situated close to all of Buffalo’s Best Attractions: Bill’s Stadium - 21 mins; Airport - 12 mins; Buffalo Outer Harbor/Downtown - 22 mins; Chestnut Ridge Park - 25 mins

Top guest favorite
The kitchen features modern stainless-steel appliances and a spacious wooden island with seating for three. Bright lighting enhances the clean lines of the white cabinetry and subway tile backsplash. Sliding glass doors provide access to the outdoor space, allowing natural light to fill the room.
Home in Cheektowaga
4.96 out of 5 average rating, 55 reviews

Serene, Renovated 2BR near Airport w/ Yard

Welcome to our bright and freshly renovated single-level home central to all in Buffalo, NY! This cozy home offers a serene and relaxing atmosphere, perfect for a short-term stay and loaded with amenities. Whether you're here for business or pleasure, our home provides all the comforts you need for a memorable stay. Book now and experience the best of Western New York! ** Mins from Buffalo Niagara Airport ** 1 mi to Walden Galleria Mall ** 9 mi to downtown Buffalo ** 10 mi to Highmark Stadium

Superhost
Home in Depew
4.75 out of 5 average rating, 12 reviews

Cozy, pet friendly, clean, quiet, close to airport

Home away from home! 1400 sq ft home with fenced in yard. Central to everything! 3mi to Airport. Close to Stadium, Arena, Niagara Falls, Downtown Buffalo, Waterfront, Wedding Venues, etc! Quiet and safe village home. Walk to the near by park that has in-ground pools, playground, volleyball and more! Upstairs loft with 2 twins and a Queen bed. Downstairs King bed suite and full bed in spare bedroom. Bring the whole family. Pet friendly! 1.5 baths. Long term stays welcome! Everything you need!

Top guest favorite
The living room features a flat-screen television mounted on the wall, with a modern black entertainment center and a small side table. Natural light enters through a window adorned with light curtains, while a patterned rug and various furnishings add to the space.
Apartment in Cheektowaga
5 out of 5 average rating, 33 reviews

Convenient cozy two bedroom apartment

Convenient newly furnished 2 bedroom apartment near Buffalo Airport, Centrally located near Buffalo and Niagara Falls. Close to University at Buffalo. Five minutes to Buffalo International Airport. Enjoy this private 2 bedroom apt. steps from a walking park & playground. Enjoy Buffalo cuisine from many local restaurants. Come cheer on the Bills or Sabres or attend one of the many festivals and music events Buffalo has to offer. The Galleria Mall is minutes away as well as supermarkets.

Top guest favorite
A single-story bungalow is showcased with a well-maintained lawn. The brick exterior is complemented by large windows that allow natural light. Neatly trimmed bushes and shrubs frame the entrance, while a pathway leads to the front door. A lamp post stands to the right, adding subtle illumination.
Home in Cheektowaga
4.94 out of 5 average rating, 103 reviews

Bungalow near BuffaloNiagara International Airport

Relax and unwind at this peaceful bungalow in suburban Buffalo. Comfortable 3-bedroom house located 2 miles from airport, 13.4 miles from Bills Stadium, 24 miles from Niagara Falls and only 15-minute drive from downtown Buffalo, NY. Two of the bedrooms are equipped with a queen-sized bed and the 3rd bedroom has a full sized bed. With plenty of storage space in the dressers and closets. Full kitchen/dining area. Laundry is available on site with a washer and dryer located in the basement.

Top guest favorite
Home in Depew
5 out of 5 average rating, 18 reviews

*HOME GYM in Neighborhood home Near Airport*

New Listing with Superhost Co-Host! Relax and unwind in this private and comfortable, home away from home, located in a quiet family-friendly neighborhood. You’ll be close to anything and everything you may need while staying in the Buffalo area! Buffalo Niagara International Airport: 10 min Wegmans: 4 min Village of Williamsville: 10 min Buffalo Niagara Medical Campus: 13 min Downtown Buffalo: 15 min KeyBank Center: 18 min Highmark Stadium: 23 min (Go Bills! 🏈) Niagara Falls: 32 min

Guest favorite
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 425 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Guest favorite
A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.
Guest suite in Lancaster
4.96 out of 5 average rating, 202 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

Superhost
A living room area features a light-colored sofa set arranged around a circular glass-top table. A dark-patterned area rug is positioned beneath the furniture. A flat-screen television rests on a simple stand against the wall, while warm light emanates from a lamp on a side table.
Apartment in Depew
4.82 out of 5 average rating, 22 reviews

Sharun’s Vacation House Near Niargafalls/Buffalo

Spacious 3-bedroom home in a prime location! Just 30 mins to Niagara Falls, 20 mins to Highmark Stadium, and within 5 mins walking distance to shops, restaurants, and all amenities. Perfect for families, groups, or long-term stays, this home offers a full kitchen, cozy living and dining areas, WiFi, smart TV, free parking, and a relaxing porch with outdoor space. Enjoy comfort and convenience while exploring all that Western New York has to offer.

Superhost
Apartment in Bowmansville
4.73 out of 5 average rating, 158 reviews

Garden House Apartment

This lovely apartment has an open layout that includes a full kitchen and comfortable living space complete with a sofa-bed and large-screen TV . There is a private bedroom with a queen size bed. The decor is an eclectic collection of color, comfort and class. This decor was chosen with the intention that you, our guests will have a cozy experience when you choose The Garden House Apartment at Old Orchard Estate.

Guest favorite
A modern living area features a dark sofa adorned with decorative cushions. A large television is mounted on a media console, while two abstract art pieces hang on the wall. Natural light enters through the nearby doorway, highlighting the warm wood flooring.
Apartment in Depew
4.86 out of 5 average rating, 78 reviews

Modern 2-bedroom upper apartment with free parking

Enjoy a stay in our updated, modern apartment! This is the perfect place for professionals on business or for couples or families visiting the area. Conveniently located within 10 minutes of the Buffalo Airport and the Galleria Mall and within 20 minutes of KeyBank Center and Highmark Stadium. You're guaranteed a great stay in our cozy modern space! Apartment comfortably sleeps four.

Popular amenities for Depew vacation rentals

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