Vacation rentals in Depew

eye pleaser

Enjoy a stylish experience at this centrally-located home. Many guests come for the Buffalo Bills games. 25 minute ride to Highmark Stadium. 7 minutes from airport. 20 minutes to downtown Buffalo. Walking distance to the village of lancaster. The village offers restaurants, bars, shopping, coffee shop, barber shop etc. around the corner from the home offers a grocery store, liquor store, consumer beverages, and a gym. Enjoy our out door patio with grill, fire pit, as well as covered side patio.

Mid-Century Modern Upper Unit

Experience the small-town charm in this centrally located Village of Lancaster property. Lancaster’s up-and-coming vibrant downtown offers access to local taproom and bodega, ample restaurant choices, and boutique shopping – all within walking distance! Looking for something to do outside the Village? This property is perfectly situated close to all of Buffalo’s Best Attractions: Bill’s Stadium - 21 mins; Airport - 12 mins; Buffalo Outer Harbor/Downtown - 22 mins; Chestnut Ridge Park - 25 mins

Serene, Renovated 2BR near Airport w/ Yard

Welcome to our bright and freshly renovated single-level home central to all in Buffalo, NY! This cozy home offers a serene and relaxing atmosphere, perfect for a short-term stay and loaded with amenities. Whether you're here for business or pleasure, our home provides all the comforts you need for a memorable stay. Book now and experience the best of Western New York! ** Mins from Buffalo Niagara Airport ** 1 mi to Walden Galleria Mall ** 9 mi to downtown Buffalo ** 10 mi to Highmark Stadium

Convenient cozy two bedroom apartment

Convenient newly furnished 2 bedroom apartment near Buffalo Airport, Centrally located near Buffalo and Niagara Falls. Close to University at Buffalo. Five minutes to Buffalo International Airport. Enjoy this private 2 bedroom apt. steps from a walking park & playground. Enjoy Buffalo cuisine from many local restaurants. Come cheer on the Bills or Sabres or attend one of the many festivals and music events Buffalo has to offer. The Galleria Mall is minutes away as well as supermarkets.

Bungalow near BuffaloNiagara International Airport

Relax and unwind at this peaceful bungalow in suburban Buffalo. Comfortable 3-bedroom house located 2 miles from airport, 13.4 miles from Bills Stadium, 24 miles from Niagara Falls and only 15-minute drive from downtown Buffalo, NY. Two of the bedrooms are equipped with a queen-sized bed and the 3rd bedroom has a full sized bed. With plenty of storage space in the dressers and closets. Full kitchen/dining area. Laundry is available on site with a washer and dryer located in the basement.

Cozy & Modern House in a Peaceful Neighborhood

Welcome to your home away from home. This beautifully maintained ranch-style residence offers the perfect balance of comfort, space, and modern convenience—ideal for both short getaways and extended stays. Located in a quiet, welcoming neighborhood, this single-family home features 1,327 sq. ft. Open-concept living space. The home includes three well-appointed bedrooms—one with a king bed and two with queen beds—making it a comfortable choice for families, groups, or business travelers.

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Clean + Efficient! Airport - 10 Min Downtown - 20

PLEASE READ ALL LISTING DETAILS Great for 1-2 people traveling for business or visiting family and friends. Centrally-located and just a few blocks from The Lancaster Village, this location has shops, restaurants and parks nearby - and is only 10 minutes to the airport and thruway access. NOTE: Apartment is accessible only by a sharply pitched staircase with narrow steps and limited foot space. Individuals with balance or mobility limitations may find them challenging.

Sharun’s Vacation House Near Niargafalls/Buffalo

Spacious 3-bedroom home in a prime location! Just 30 mins to Niagara Falls, 20 mins to Highmark Stadium, and within 5 mins walking distance to shops, restaurants, and all amenities. Perfect for families, groups, or long-term stays, this home offers a full kitchen, cozy living and dining areas, WiFi, smart TV, free parking, and a relaxing porch with outdoor space. Enjoy comfort and convenience while exploring all that Western New York has to offer.

Garden House Apartment

This lovely apartment has an open layout that includes a full kitchen and comfortable living space complete with a sofa-bed and large-screen TV . There is a private bedroom with a queen size bed. The decor is an eclectic collection of color, comfort and class. This decor was chosen with the intention that you, our guests will have a cozy experience when you choose The Garden House Apartment at Old Orchard Estate.

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Modern 2-bedroom upper apartment with free parking

Enjoy a stay in our updated, modern apartment! This is the perfect place for professionals on business or for couples or families visiting the area. Conveniently located within 10 minutes of the Buffalo Airport and the Galleria Mall and within 20 minutes of KeyBank Center and Highmark Stadium. You're guaranteed a great stay in our cozy modern space! Apartment comfortably sleeps four.