Vacation rentals in Depew

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Top-rated vacation rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The front entrance of the property features a welcoming porch with decorative railings and vibrant flower beds. A large American flag and other banners hang from the porch, while colorful flowers provide a lively accent. The pathway is well-maintained, leading to the main door.
Guest suite in Buffalo
4.99 out of 5 average rating, 956 reviews

Sleep Under The Stars

Through hard work and dedication, my listing has been ranked in the TOP 1%🏆of all Airbnb listings worldwide. The space I offer is an ENTIRE 2nd floor "MINI SUITE". The living quarters include a PRIVATE BATHROOM, BEDROOM, DEN & CAFE'. The space is ALL YOURS to enjoy & the extras are plentiful. Coffee, water, fresh fruit, yogurt, & snacks/candy are available. My goal & Mission Statement is to provide a nice comfortable landing spot, & offer helpful advice & valuable insight to my cherished guests

Superhost
A cozy sleeping area features a spacious bed with a light-colored coverlet. Decorative pillows are arranged at the head of the bed, complemented by bedside tables and lamps. Natural light filters through sheer white curtains, enhancing the calming ambiance of the room.
Guesthouse in Cheektowaga
4.8 out of 5 average rating, 152 reviews

Warm & Cozy private Guesthouse/ Entire place.

Hi there! This is Aklima and Farhad, and we’re thrilled to have you stay at our guest house. It’s connected to our house, but both have their own private entrances. Just a friendly reminder, you might spot our kids playing in the backyard, so please be mindful of that. We love living here and meeting new people, which is why we started Airbnb. We’re committed to providing the best hospitality at an affordable price. This place is surrounded by nature and in a peaceful area! Enjoy your stay!

Guest favorite
A living area is displayed, featuring a dark sofa alongside a patterned armchair. A decorative area rug covers the wooden floor. The background shows a kitchen space with bar seating and modern appliances, contributing to a welcoming atmosphere.
Apartment in Cheektowaga
4.94 out of 5 average rating, 231 reviews

Close to Niagara Falls and Airport, Mall nearby

Niagara Falls is only 30minutes away.Very nice neighborhood. 4minutes from Galleria Mall.Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 plus we have a clean pack and play for your little one. Has own keypad entrance. Full sleeper sofa in living room. One bedroom has a queen bed and tv. The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly. Pets can do their business out front. There are dogs that use the back yard.

Top guest favorite
A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.
Guest suite in Lancaster
4.98 out of 5 average rating, 183 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our dog Toby & our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

Guest favorite
The living area is furnished with modern, comfortable seating arranged around a wall-mounted 55-inch smart TV. Two large windows allow natural light to fill the space, offering views of the outdoors. A small dining table is nearby, enhancing the open layout.
Apartment in Buffalo
4.94 out of 5 average rating, 108 reviews

Cozy stay in S. Buffalo • 10 min to Bills Stadium

Welcome to our cozy, fully remodeled upstairs studio in the heart of South Buffalo! Enjoy a prime location just 10 minutes from the Buffalo Bills Stadium, with concerts, nightlife, restaurants, casinos, and Niagara Falls all within a 10-20 minute drive. The apartment boasts a fully equipped kitchen, a comfortable pillow-top queen bed, a living area with a 55-inch smart TV and electric fireplace, and a spacious bathroom. Enjoy the convenience of a laundry room with a washer and dryer.

Superhost
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 409 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Top guest favorite
A comfortably arranged living area features two light gray sofas adorned with decorative pillows, set around a round black coffee table. Natural light enters through the large windows, illuminating a woven area rug on the hardwood floor, while lamps provide soft ambient lighting.
Guest suite in Williamsville
4.95 out of 5 average rating, 307 reviews

**Village Home In Buffalo- BEST LOCATION!**

Welcome “home” and discover why Buffalo is called the ‘City of Good Neighbors’! Whether it’s for a day, week, or even longer, feel comfortable and cozy, in this 1 bedroom apartment. Being less than 2 miles from the Buffalo Niagara Int’l airport, a quick Uber ride will bring you to Williamsville and offer you a true Buffalo experience. Enjoy the small town vibe of the village, and allow Williamsville to be your gateway to adventure! (Downtown Buffalo- 9mi, Niagara Falls- 17mi. )

Superhost
A living area is shown with a light-colored sofa and a brown ottoman placed in front. A dark armchair with a patterned cushion adds contrast. A tall green plant is positioned beside a window, enhancing the natural light in the room. Neutral wall colors contribute to a calm atmosphere.
Apartment in Depew
4.87 out of 5 average rating, 23 reviews

Clean + Efficient! Airport - 10 Min Downtown - 20

PLEASE READ ALL LISTING DETAILS Great for 1-2 people traveling for business or visiting family and friends. Centrally-located and just a few blocks from The Lancaster Village, this location has shops, restaurants and parks nearby - and is only 10 minutes to the airport and thruway access. NOTE: Apartment is accessible only by a sharply pitched staircase with narrow steps and limited foot space. Individuals with balance or mobility limitations may find them challenging.

Guest favorite
A spacious kitchen features warm wooden cabinetry and modern stainless steel appliances. Natural light floods through windows, illuminating the open layout that connects to a cozy living area. A decorative light fixture hangs from the vaulted ceiling, enhancing the inviting design.
Home in Buffalo
4.95 out of 5 average rating, 134 reviews

KING BED! Brand New! Fabulous & Fresh Farmhouse!

Top to bottom BRAND NEW home! Custom interior design & a relaxing, SPARKLING space! KING primary en-suite w/ walk in closet! 1st floor laundry, kitchen w/ every cooking amenity possible- coffee/tea bar, filtered water & ice on fridge, FREE parking & WIFI, private yard; deck w/ gas grill & fire pit, family friendly-high chair & pack n play available! Minutes from TONS of malls & yummy restaurants. Close to airport & train station. Dead End Street!

Top guest favorite
The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.
Guest suite in Lancaster
4.91 out of 5 average rating, 186 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Top guest favorite
A charming exterior view showcases a white picket fence surrounding a well-kept yard. A lush green lawn is framed by flower beds, and a gazebo is visible in the background, complemented by mature trees providing shade.
Apartment in Williamsville
4.95 out of 5 average rating, 146 reviews

Cozy Williamsville apartment at Madison Place

Cozy 1 bedroom 2nd floor apartment Eat in kitchen with countertop height seating 2 Queen size beds (bed & fold out couch) Brand new built in dishwasher & microwave oven All cookware, silverware & kitchen appliances Fully furnished with all linens, towels and starter supply of soaps, shampoos. Ample closet space and storage Whole house water filter Laundry located in basement Off street parking for 2 cars

Top guest favorite
A cozy corner features a brick fireplace, framed by decorative plants and two lace-covered windows. A small wooden table stands beside the fireplace, adorned with a candle and vintage items. Nearby, a set of folding chairs is positioned next to a framed floral artwork.
Apartment in Buffalo
4.92 out of 5 average rating, 270 reviews

Peaceful, spacious apartment. Non-smoking.

Traditional South Buffalo lower in the Irish Heritage District. NOT suitable for children aged 1-12. NOT pet-friendly. 10 minutes from Canalside, Key Bank Center, Sahlen Field, Harbor Center, Riverworks and downtown. 20 minutes from Highmark Stadium. 30 minutes from Niagara Falls. Stumbling distance from the Buffalo Irish Center.

Popular amenities for Depew vacation rentals

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