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Vacation rentals in New Melle

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Top-rated vacation rentals in New Melle

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A comfortable living room features a sectional couch, light hardwood flooring, and a patterned area rug. A flat-screen TV is mounted above a brick fireplace. Natural light enters through windows adorned with light curtains, while a dining area with chairs is visible in the background.
Home in Wentzville
4.93 out of 5 average rating, 131 reviews

Cozy Home in Wentzville Sleeps 6 + Game Room

Welcome to your home away from home in Wentzville, Missouri! Families and furry friends are welcome to our cozy, centrally located home. Sleeps 6- 1 King , 1 Queen, and 1 Sleeper Sofa Full sized bed Fully equipped Kitchen with everything you need to create a delicious meal, or a cup of coffee Game room and Laundry located in the basement- 60 game free play arcade machine and foosball! Roku friendly TV located in both bedrooms, living room and on the Patio Fully Fenced Yard with Fire Pit

Top guest favorite
A charming farmhouse is framed by lush green trees, displaying a welcoming front porch. The exterior showcases a muted gray siding with white accents, while a well-maintained lawn surrounds the home, enhancing the sense of tranquility in this rural setting.
Home in Augusta
4.99 out of 5 average rating, 276 reviews

Katy Trail Farmhouse - 3 bd/2.5 bath - Amazing!

DIRECTLY ON THE KATY TRAIL! Quaint 1943 farmhouse on 7 private acres in Missouri wine country - halfway between Klondike Park & the town of Augusta. Loads of farmhouse charm w/ the amenities & comforts of home. Spacious & well-appointed, 3 bedrms/2.5 baths. Walk-in/out or bike-in/out to KATY trail -- the location is perfect. Enjoy a sunset dinner & live music at one of the many wineries – or relax on one of the two screened-in porches & clear your mind. No other place like it in Augusta!

Top guest favorite
The charming front porch features a white wicker chair and a decorative wreath, inviting relaxation. Greenery surrounds the entryway, complemented by a well-maintained lawn. A gravel pathway leads from the porch to the driveway, creating a welcoming entrance to the guest house.
Home in Saint Charles
4.97 out of 5 average rating, 761 reviews

301 Guesthouse- Historic Main street-Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Top guest favorite
The outdoor pool area features a serene pool surrounded by a spacious deck. Lounge chairs are positioned around the pool, and a large umbrella provides shade over seating areas. Lush greenery borders the space, creating a peaceful atmosphere.
Home in Augusta
5 out of 5 average rating, 40 reviews

"The Villa" at Villa Augusta in MO wine country

Villa Augusta is a Tuscan inspired home atop a hill on 30 acres in beautiful MO wine country. The location is perfect to experience the best of wine country with many wineries just 5-10 miles away. There are 2 separate and private spaces for guests to enjoy Missouri Wine Country. Enjoy the 2BR/2BA known as "The Villa" on the entire 2nd floor, or check out "The Cellar." our other listing. Return from a day enjoying the wineries or biking the Katy Trail and relax in the pool, spa or fireside.

Guest favorite
Chalet in Innsbrook
4.95 out of 5 average rating, 132 reviews

Relaxing Lakefront Chalet in Innsbrook Resort

Nestled in the woods overlooking Foxfire Lake, this A-frame offers the perfect four-season escape. When the snow falls, it transforms into the quintessential winter retreat. Cozy up beside the stone fireplace, where views of the lake are framed by frosted trees. As the weather warms, the lake calls! Enjoy direct access to Foxfire Lake from our private dock. Spend your days fishing, swimming, or simply basking in the sun. This chalet will help you find joy and relaxation, whatever the season.

Guest favorite
Home in O'Fallon
4.93 out of 5 average rating, 57 reviews

Westhoff Cottage

Cozy 2BR O’Fallon home sleeps 6 adults plus children with 2 queen beds, pull-out sofa, floor mattress (great for kiddos!) & pack n play available upon request. Pet-friendly with large yard! Fast WiFi, fully stocked kitchen, flatscreens in every room. Super clean, quiet street, easy Highway 70 access and only 23 min to Lambert Airport. Perfect for families, business travelers, relocations & traveling nurses. Seamless check-in and affordable rates. Everything you need for a comfortable stay!

Top guest favorite
A treehouse-style rental is nestled among vibrant autumn foliage, with wooden steps leading up to the entrance. The structure features a private front porch, framed by surrounding trees and a gravel path, conveying a natural and serene atmosphere.
Guest suite in Dardenne Prairie
4.88 out of 5 average rating, 338 reviews

Treehouse Spa Suite

Treehouse Day Spa is nestled on 3 wooded acres in St.Charles County. There is a subdivision next to me but I have my trees!!! Get away from it all while being close to it all at the same time. Augusta wineries, Main Street St. Charles and the Streets of Cottleville are all within minutes of the location! There are two rental units in the treehouse: The spa suite and the penthouse. They each have a separate entrance and are private spaces. Recharge your battery! Regroup Relax Refresh

Guest favorite
Cabin in Defiance
4.95 out of 5 average rating, 144 reviews

Hillside Cabin on 43 Acres w/ Private Lake & View!

Free from modern distractions, this 1-bedroom, 1-bath cabin in the heart of wine country is the perfect place to unplug and reconnect with nature! Immersed in lush woodlands, this cabin comes with all the amenities needed for a peaceful retreat, including a fishing lake (no license required!), resident horses, and fully equipped kitchen. Watch the horses and sunrise from the porch swing before venturing off to the Katy Trail or head to one of the many wineries located just minutes away!

Top guest favorite
A comfortable leather futon is positioned in the living area, complemented by a wooden coffee table with storage. Decorative pillows add a touch of charm, while a wall clock and bicycle artwork provide visual interest. Warm lighting enhances the inviting atmosphere.
Guest suite in Wright City
4.83 out of 5 average rating, 137 reviews

Country Private Suite, L Level, Laundry, Hot Tub

Beautifully decorated warm cabin feel. Spacious bedroom with nice desk for your laptop work space. Bathroom has washer and dryer. Living room has thick-cushioned leather futon for second bed, counter space with microwave/air fryer, paper products, and kuerig coffee maker, new 5’ fridge, 50” flat screen TV. Access to outdoor hot tub. Internet was weak so affected some reviews but is super fast now. Near Cedar Lake Winery, Big Joel’s Safari, Long Row Lavender Farm, and Pumpkins Galore

Guest favorite
Home in Dittmer
4.96 out of 5 average rating, 628 reviews

Honeymoon Suite at Camp Skullbone In The Woods

Experience a romantic, quiet, and cozy chalet designed for two! This charming retreat features vintage décor and all the modern amenities you need for a comfortable stay. Unwind indoors by kicking back and watching a movie, surfing the web, curling up with a good book or a friendly board game, or sharing a drink with that special someone. In the evening, relax on the cozy deck under the stars, basking in the warm glow of the gas fire pit or unwinding in the inviting private hot tub!

Guest favorite
A modern living area features large windows allowing natural light and views of the surrounding trees. Plush seating surrounds a circular table, and a spiral staircase leads to the upper level. The outdoor space includes a grill and seating arranged around a fire pit.
Home in Gray Summit
4.96 out of 5 average rating, 52 reviews

Cabin+LAKE! Fish-swim-kayak*Near Purina & SixFlags

Are you looking for that perfect little spot for your romantic getaway? Maybe a girls trip, a weekend of fishing with the boys, or just need some family fun on the water? Then come check out our cabin and spot on the lake! You can get away from it all & still be close to everything STL has to offer. This home has been completely updated from top to bottom and you’ll have access to a 12 acre lake, perfect for soaking up some fun in the sun. Fish, swim, kayak, play - you deserve it :)

Top guest favorite
An open living space is highlighted by vaulted wooden ceilings and large windows allowing natural light to flood in. A stone fireplace acts as a focal point, complemented by modern furniture. A staircase leads to a loft area, while polished wooden flooring adds warmth.
Chalet in Innsbrook
4.98 out of 5 average rating, 146 reviews

Early Check-in, Late Check-out on Weekends 8AM-8PM

Just 45 minutes from St. Louis, Innsbrook Resort is a 7,500-acre woodland community with over 100 lakes. As a guest of Innsbrook, you'll have access to all of the resort amenities, entertainment, and dining areas. After a fun filled day of activities, you will enjoy unwinding at Ella's Roost, a two bedroom + sleeping loft, two-bathroom waterfront chalet. Both bedrooms have a queen size bed and the three-person sleeping loft offers a bunk bed and a futon.

Popular amenities for New Melle vacation rentals