Hotel vacation rentals in Missouri

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Top-rated hotel rentals in Missouri

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Guest favorite

A charming outdoor area features a wooden pergola draped with greenery and hanging plants. A turquoise door adds a pop of color, while a vintage bicycle leans against the structure. The surrounding space includes potted plants and outdoor tables, creating an inviting atmosphere.

Hotel room in Ironton

5 out of 5 average rating, 10 reviews

The King Suite at Pickle & Perk

Located on Main Street in the heart of The Valley. Tucked above our locally loved coffee bar, a cozy king suite perfect for solo travelers or couples looking for a quaint, bed-and-breakfast style escape. Featuring a plush king bedroom, a full private bathroom with a stand-up shower, and a kitchenette equipped for light bites and midnight snacks. A private entrance opens directly into our caged courtyard, giving you a quiet, off-the-street entrance and a peaceful nook to enjoy your morning brew.

Guest favorite

A well-lit bedroom features a spacious bed with minimalist bedding. A flat-screen TV is mounted above a sleek nightstand. A small desk and chair are positioned near the window, which provides access to a large balcony. The walls are adorned with framed artwork, enhancing the room's décor.

Hotel room in Washington

4.95 out of 5 average rating, 126 reviews

River Sirens Hotel Deluxe Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.

Guest favorite

A modern bathroom is presented, featuring a white countertop with a sleek sink and large mirror. Soft towels hang on the wall alongside a fluffy rug on the floor. A cabinet with storage space adds functionality, while bright overhead lights provide ample illumination.

Private room in Gerald

4.9 out of 5 average rating, 164 reviews

Enjoy your stay at the Rock Island Whistle Stop.

You will enjoy this cozy get away. The retro kitchen and new upscale bath blends into down home comfort. Records playing and Roku streaming offer a bit of the old and new in a quaint studio apartment. Awesome sunrises and starry nights, crackling fire on the patio, in two acres of woods, creates a step back into nature. Just one block off US Hwy 50, by the Rock Island Trail State Park, it is the perfect B & B. For guests staying Saturday and Sunday, breakfast is included at our Gerald Cafe.

Guest favorite

The rooftop hot tub is set against a vibrant sunset sky, creating a serene atmosphere. An expansive view of the surrounding cityscape is visible from the tub, emphasizing a tranquil space for relaxation.

Hotel room in St. Louis

4.97 out of 5 average rating, 35 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Top guest favorite

The covered outdoor area is adorned with string lights, creating a warm ambiance. Picnic tables and colorful chairs invite social gatherings. A nearby green garden hose rests beside a decorative orange rain barrel, with the backdrop of a well-kept yard and a visible kitchen counter.

Hotel room in Springfield

4.94 out of 5 average rating, 216 reviews

“Camp Rockwood”at Rockwood Motor Court on Route 66

Rockwood Motor Court, on historic Route 66, was built in 1929. Each room is themed and furnished to the era of Route 66. Camp Rockwood pays homage to the important history of motor courts along the road. It is decorated with historic photos of Rockwood and other courts and motels. Newly renovated in 2019, you’ll enjoy clean and comfortable room amenities while experiencing authentic motor court lodging. Need more space? We have larger rooms or can package multiple rooms for your group.

Guest favorite

A walk-in rain shower features contemporary gray tile walls and a textured tile floor. Clear glass doors provide an open view of the spacious shower area. A shelf for toiletries is mounted on the wall, and natural light enters through a nearby window.

Hotel room in St. Louis

4.85 out of 5 average rating, 765 reviews

The Maple Room Queen Bed at BnB in CWE!

A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Guest favorite

A spacious studio features high ceilings and large industrial windows that allow natural light to fill the room. Modern furniture includes a comfortable sofa and a bed with a striped blanket. The kitchen area is equipped with black appliances, showcasing sleek cabinetry and a dining table.

Hotel room in St. Louis

4.91 out of 5 average rating, 121 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Guest favorite

The room features a wooden bed frame with a soft mattress, adorned with a plaid blanket. Exposed brick walls provide a rustic backdrop, complemented by two framed artistic pieces. A cozy seating area is visible, with a small ottoman adding functionality.

Hotel room in Hannibal

4.96 out of 5 average rating, 134 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Top guest favorite

A group of people gather around a firepit, roasting marshmallows. The warm glow from the fire contrasts with the twilight sky. Stone seating is arranged around the fire, and a deck is visible in the background.

Hotel room in Preston

5 out of 5 average rating, 27 reviews

Front Motel Room

You won’t want to leave this charming, one-of-a-kind place. Ample parking for trailers! We’re located 2.5 mi from the Weathered Wisdom barn, 10 mi from Pomme De Terre lake, 14 mi from Lucas Oil Speedway! Enjoy your own Motel room with outside entrance only, with a full private bath and queen bed.. The property is quiet and nestled in the woods.. We have 2 motel rooms and a bunkhouse available! Enjoy a morning cup of coffee on our deck! Look for the White Oaks signs!

Top guest favorite

The entrance of the room features an antique-style table with decorative items and a lamp. A round mirror hangs above the table, reflecting the warm light. The door, labeled '7,' provides access to the room, with a soft carpeted area nearby.

Hotel room in Eldon

4.95 out of 5 average rating, 44 reviews

#8 A 1930’s Motor Court, Historic Randles Court

Family owned and operated! Built in the early 1930s, our recently restored rooms will take you back to simple times. The days of bus & railway rest stops, road-trips in the family car, and the quintessential motor court. Our town is alive with new and old businesses alike - places to eat, shop, and play for everyone in the family! We’re centrally located in downtown Eldon-just 15 minutes from the Lake of the Ozarks and 30 minutes from Jefferson City.

Top guest favorite

The bathroom features a spacious jacuzzi tub surrounded by dark blue tiles, complemented by a small decorative plant and a vase with fresh flowers on the window sill. Natural light enters through the window, which is dressed with muted shades, adding a serene touch.

Hotel room in Ste. Genevieve

4.97 out of 5 average rating, 32 reviews

Dr. Hertich’s House - The Governor's Suite

Enjoy easy access to popular shops and restaurants from this charming place to stay. Step back in time and discover the enchanting history of the Dr. Hertich House with a cozy stay at The Hertich House Heritage Hotel in Ste. Genevieve, MO. The Governor's Suite welcomes guests with a blend of old-world charm and modern comforts, such as a private jacuzzi tub and romantic fireplace.

Top guest favorite

A modern bathroom is presented with a sleek, tiled design in neutral tones. A white bathtub is positioned against one wall, complemented by a handheld showerhead and a wall-mounted shower fixture. Functional storage niches are built into the wall for toiletries.

Hotel room in Blackwater

5 out of 5 average rating, 47 reviews

Cozy Coffee Shop Stay!

You won’t want to leave this charming, one-of-a-kind place. Located above an award winning coffee shop in beautiful, picturesque Blackwater, MO. This 1 bed, 1 bath rental is located in a historic building. This is an old building so it will have imperfections, but what it lacks in perfection, it makes up for in charm.