Family-friendly vacation rentals in Mission Bay

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Top-rated family-friendly rentals in Mission Bay

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A bright living space features a large sectional sofa adorned with orange cushions, complemented by a colorful area rug. A wooden coffee table sits in front, and a wall-mounted art piece adds a touch of elegance. Large windows provide skyline views and abundant natural light.
Loft in South of Market
4.98 out of 5 average rating, 140 reviews

Inspiring Skyline Views From a Hip Loft in SoMa

Brew coffee in a kitchen with bold wood cabinets, then curl up with a book on a cushioned bench set along floor-to-ceiling windows offering skyline views. Modern furnishings and colorful decor forge a trendy vibe within this bright loft apartment. The loft has all imported fixtures and finishes from Italy. It has Ralph Lauren deep brown carpet on the stairs and in the bedroom/office and polished concrete on the main level. There is also remote controlled blinds on the main windows and skylights. Access to the whole area described in the Summary. I can be available 24/7 at least the first and last day of their stay. Though likely at all times. The South of Market (SoMa) neighborhood has a lot of restaurants, bars and night clubs to enjoy. It is also very close to the Moscone Center. 3 1/2 blocks away from Civic Center BART/Muni Station. 20 minute walk to downtown. 4 blocks away from Moscone Center. 20 minute walk to AT&T Park SoMa is a hip neighborhood with a ton of restaurants to choose from, bars and night clubs, start-up companies around, close to the Moscone Center.

Top guest favorite
A spacious bedroom is illuminated by natural light, featuring a minimalist wooden bed with gray bedding. A large artwork hangs above the bed, while a potted plant and small reading lamp add detail. A desk and chair are positioned nearby, enhancing the workspace.
Guest suite in Mission
4.99 out of 5 average rating, 196 reviews

Large Light Filled Quiet Artist built 2BR Apt

Large, light filled, quiet, private 2 bedroom apartment/guest suite with split bathroom (toilet and sink in one room, soaking tub/shower and sink in other), kitchenette, and ceilings up to 16'. We have been working on this space for the last 2 years to get the details just right, including hand built furniture and art by local artists. Above the din of the Mission, this apartment is a unique space built in the attic of a large Edwardian house run by artists Laurel Roth Hope and Andy Diaz Hope .

Top guest favorite
A tranquil garden area features lush greenery, with tropical plants surrounding a private hot tub. Soft lighting highlights the space, creating a serene ambiance. A pathway leads to the entrance of the suite, ensuring privacy and easy access for guests.
Guest suite in Mission
4.98 out of 5 average rating, 267 reviews

Mission Private 1BR/BA Garden Suite Separate Entry

Luxury garden suite w/ private entrance, private bathroom, and hot tub in one of SF's hottest neighborhoods - the Mission. No shared spaces in this quiet Inner Mission one-bedroom w/ large living room, Xfinity, Apple TV, hi-speed Wi-Fi. Lots of room to spread out & relax. Strict cleaning regimen incl 30-min UVC light treatment per room, min 24-hour vacancy, sterile wipe down of all common surfaces. Please check our location on map relative to places you plan to visit in SF. Please: no smoking.

Guest favorite
A fully equipped kitchenette features a blue retro-style refrigerator and a stainless-steel sink with a modern faucet. Natural light enters through two windows overlooking a shared garden, while a door provides direct access outside, enhancing the airy atmosphere of the space.
Apartment in Portola
4.91 out of 5 average rating, 232 reviews

Garden studio oasis w/ kitchenette & private entry

Cosy, comfortable, and quiet unit with direct access to a lovely garden. 10 min. from the airport, 30 min. from downtown via express bus. Well-connected, sunny neighborhood. Free street parking. Views of the bay, mature redwood trees, easy to get to attractions. Walking distance to bustling food corridor, with restaurants, cafes, grocery stores, ATMs, pharmacy, salons, library, and more. Blocks from largest park in the city with sweeping views, historic greenhouses, and unique Freeway Greenway.

Top guest favorite
A cozy living area features wooden walls and vibrant floral curtains. A comfortable sofa in light grey is adorned with patterned cushions. A small table sits in the center, complemented by a softly lit floor lamp. Large glass doors open to a lush garden space.
Guest suite in Mission
4.95 out of 5 average rating, 133 reviews

Stylish Garden Suite with a dash of Vintage

SO CLOSE to SO MUCH...ice cream, coffee, food, cocktails, murals, markets, music, etc. You’ll love my place because its location is in heart of the Mission. The in-law unit is cozy, comfortable, and stylish. The garden is lovely! It's great for couples, mini-sized families, solo adventurers, and business travelers. This is a very walkable neighborhood. Note: Although private, this unit is below my house and connects by a shared laundry area and hallway. See House Manual and images for details

Top guest favorite
A bright living area features large bay windows fitted with bamboo shades, allowing natural light to flood the space. A plush sectional sofa is complemented by a round glass table and artful decor, including framed artwork and decorative urns on pedestal shelves.
Apartment in Mission Bay
4.98 out of 5 average rating, 566 reviews

Fabulous Artist Flat in the Heart of Potrero Hill

Decorated in the eclectic bohemian spirit of San Francisco, the living space is filled with original artwork, vibrant colors and souvenirs from travel. The flat, with its easy-going creative vibe, could be the place you discover inspiration for your next project. The flat is clean, comfortable and filled with eclectic artistic touches to the delight of our guests. Please no shoes worn inside. *Note there is temporary construction in basement of the building, which can be noisy 10:30am-5pm.

Top guest favorite
A compact kitchen showcases modern amenities, including a sink, induction hotplate, microwave, and mini fridge. A wooden breakfast bar is equipped with two stools, and a large window allows natural light to illuminate the space while providing a view of the outdoors.
Guest suite in Bernal Heights
4.97 out of 5 average rating, 540 reviews

Live like a local and try tiny living

At just over 100 sq ft, experience tiny living in our cozy space. The small space is priced accordingly, we are one of the cheaper places to stay in SF. You'll have a private room with a bathroom and queen Murphy bed that pulls over a couch. We are in the middle of Bernal Heights, a quiet and quaint neighborhood with amazing views of downtown San Francisco from the top of the hill. We are two blocks away from shops, cafes and restaurants, it's very walkable. Come stay and live like a local!

Top guest favorite
A modern studio space showcases a comfy bed adorned with neutral-toned bedding. A small dining table is accompanied by stylish chairs. Large windows allow for ample natural light, while greenery is visible outside. A sleek couch and minimalist decor complete the welcoming atmosphere.
Guest suite in San Francisco
4.95 out of 5 average rating, 198 reviews

Modern Bernal Heights studio-Private outdoor patio

Welcome to my modern studio with private entrance, walk-in closet, bathroom, kitchenette, and peaceful outdoor space with outdoor dining set, grill, and lounge chairs. Located on a quiet street in the Bernal Heights area and a 5min walk to Bernal Hill outdoor space, 20min walk to the shops, bars/restaurants on Cortland Avenue, 10min walk from Precita Park with local cafes, grocery store, & beautiful Park. It’s HILLY Note. kitchenette is outside the unit in private closed-off space in garage

Guest favorite
A spacious bedroom is featured with a large bed covered in a colorful patterned blanket. Two lamps are positioned on each side of the bed, and artwork depicting the Golden Gate Bridge adorns the walls. Natural light streams in through a window dressed with white curtains.
Home in Portola
4.91 out of 5 average rating, 537 reviews

Spacious & Clean Apartment on Traditional SF Hill

Downstairs unit/private entrance Bright downstairs unit w/master bedroom & living room or bedroom-you choose. Private entrance. Private bath. Fridge, but no kitchen. High-speed Wi-Fi, & antenna TV. Perfect for larger groups & can sleep 5. Parking is FREE in the neighborhood & the home is located in the transitioning, yet up & coming Portola neighborhood, which is 21 min. to downtown & 16 min. from the airport! Please Note: We live in upstairs unit & you can hear our footsteps at times.

Guest favorite
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.85 out of 5 average rating, 126 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Top guest favorite
A charming two-story house is presented, featuring a striking grey exterior with white trim. Double garage doors are visible at the base, and a series of steps lead to a welcoming front porch. Large windows enhance natural light, and greenery adds a touch of warmth.
Guest suite in San Francisco
4.93 out of 5 average rating, 403 reviews

Live Like a Local in Sunny Bernal Heights

Located close to the Mission and Potrero Hill, our 2 bedroom (approx 1000 sq.ft.) rental is near great restaurants, unique shopping, and the newly opened Chase Center. This 2 bedroom unit is well-stocked with everything you'll need to have a relaxing and fun-filled stay in San Francisco. There's easy access getting into and out of our neighborhood and our street has ample parking. We love to host and are excited to meet new people eager to explore all that the Bay Area has to offer!

Top guest favorite
A comfortable seating area features a light-colored sofa adorned with decorative cushions and a wooden coffee table. A beige armchair complements the space, while a bookcase showcases various items and framed art adds a personal touch against the soft yellow walls.
Guest suite in Bernal Heights
4.93 out of 5 average rating, 337 reviews

Audrey & Nick's Place

Audrey and Nick’s place is a comfortable, spacious studio with a private entrance, and all the comforts of home. It is located in the renovated basement of a 19th century farmhouse and is fully apportioned with a queen size bed, a large bathroom with a deep tub and access to both front and back yards. It has all the basics, and then some. It is a perfect base of operations for days and nights on the town or around the Bay and a great place to stay in and get things done.

Popular amenities for Mission Bay family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Mission Bay

  • Total vacation rentals

    Explore 20 vacation rentals in Mission Bay

  • Nightly prices starting at

    Mission Bay vacation rentals start at € 129 per night before taxes and fees

  • Verified guest reviews

    Over 250 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Mission Bay vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission Bay rentals

  • 5 Average rating

    Mission Bay stays are highly rated by guests—averaging 5 out of 5!