
Vacation rentals in Lee County
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Lee County
Guests agree: these stays are highly rated for location, cleanliness, and more.

Waterfront Hideaway
This picturesque Airbnb is a hidden gem nestled along a canal, one minute boat ride to the Caloosahatchee River. The living room, bathed in natural light is perfect for taking in the scenic views. The spacious bedroom has a king-size bed, ensuring a night of blissful rest. The full kitchen is equipped with all modern appliances. Close to Sanibel & Fort Myers Beach. Bring your boat & dock it on the seawall, ready to set sail whenever your heart desires. Book now - your coastal paradise awaits!
4.98 out of 5 average rating, 249 reviews
McGregor’s Gem• Heated Pool 3BR/2BA River District
🌴 Welcome to McGregor’s Gem—your ideal Southwest Florida retreat! Dive into relaxation in your private heated pool, spread out across three bedrooms and two baths, and enjoy the perfect blend of peaceful tree-lined neighborhood living just minutes from the charming Downtown Fort Myers River District, world-class beaches, and top local attractions.☀️ Whether you’re traveling with family, friends, or on business, this home offers all the modern comforts you need for a relaxing, stress-free stay
4.96 out of 5 average rating, 147 reviews
LUX Villa w/ Private Salt Water Pool, Lanai, Canal
Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!
4.99 out of 5 average rating, 266 reviews
Boater’s Paradise-Stunning Sunsets! Games Room!
Renovated lanai! This 3 bed/4 bath home is on the nicest canal with 200+ ft of frontage & gorgeous views of the canal & sunset. The pool, tiki hut & docks have full sun all day. Each bedroom has a private bath & there's a 2 pc powder room off the laundry. The primary has a king bed & walkout to pool. The 2nd bedroom has a queen bed & pool access. Bedroom 3 has a queen & private bath. Fully equipped kitchen with everything you need. And a games room! Enjoy stunning sunsets under the tiki hut.
4.97 out of 5 average rating, 146 reviews
Gulf Access | Heated Pool | Spa | 2x Kings Beds
Escape to this 5-bed, 3-bath oasis in Cape Coral’s canal system, just minutes from the Gulf of Mexico by boat. Relax in the lanai-covered saltwater pool and hot tub, surrounded by tropical landscaping. Perfect for families, pets, and biz travel, the home features a spacious kitchen, multiple TVs, cable TV, and water views. Just 5 mins to beaches, 10 mins to dining & shopping, and 35 mins to Fort Myers Airport—your ultimate Florida escape awaits! Moderate cancellation policy & no cleaning fee!
4.92 out of 5 average rating, 156 reviews
Paradise on Estero Bay
Welcome to Mullock Creek a Boater's dream! Southwest views boasting breathtaking sunsets overlooking gulf access canal from your spacious backyard, just minutes away from shopping and dining at Coconut Point, and Gulf Coast Town Center. This stunning Key West Style home has been beautifully maintained and updated offering a lovely front entrance, fully equipped kitchen, spacious Living Room, dining room, Wi-Fi, private driveway with access to the open garage, fully furnished and private pool.
4.94 out of 5 average rating, 163 reviews
Amazon Bungalow near Sanibel & Fort Myers Beach
Tropical setting. Peaceful/quite neighborhood. Bunche Beach 2 miles, Sanibel Island 3.5 miles, Fort Myers Bch 5 miles. Home is set up as a duplex, with TWO COMPLETELY SEPERATE & PRIVATE entrances, kitchens, living rooms, bedrooms, bathrooms & laundry rooms for COMPLETE PRIVACY. The Bungalow is a 1 King bed, 1 full bathroom & shower with large living room, kitchen & porch. Perfect for Couples! • 1/2 mile to Restaurants and Shopping • Close to Shellpoint Golf-Course • FREE Wi-Fi and Cable-TV
4.82 out of 5 average rating, 331 reviews
Heated Pool + Hot Tub |3BR | Large Pool|Sleeps 10
•Prime Location: Just minutes from Sanibel & Captiva Islands • 10-minute walk to movie theaters, shops, and restaurants • 8 min to Fort Myers • 10 min to Cape Coral Water Park • 25 min to the airport • Perfect for families & remote work • 5 Smart TVs • Fast Wi-Fi • Family-friendly amenities & games • Fully equipped kitchen • Washer & dryer • Sofa bed • Beach towels & bathrobes • Outdoor living: • BBQ grill • Outdoor dining area • FREE onsite parking • Easy self check-in
4.96 out of 5 average rating, 101 reviews
NEW! Beachfront!3BR Suites Sustainable Home+Dock
NEW LISTING!! 💰No nickel & diming—AirBnb & cleaning fees included! 🚤 Boat-access-only retreat with private dock 🏖️ Steps to pristine beach 🌊 Panoramic water views from every room 🛏️ 3 private queen ensuites 🍽️ Premium kitchen + grill ☀️ Tesla solar + 🚀 Starlink WiFi 🛁 Breathtaking sunset views 🛶 Kayak, SUP & e-bikes included 🌿 Surrounded by protected preserve; only one nearby home 🐬 Incredible wildlife viewing ✨ Perfect for nature lovers, anglers & tranquility seekers
5.0 out of 5 average rating, 13 reviews
Bohemian Bungalow / Washer + Dryer / Private
Your family will be close to everything when you stay at this centrally-located place. Stylish, yet comfortable - You have access to an additional spacious sun patio, a washer and dryer, and ample back and front yard. 10 miles to the beach, biking distance to Historic Downtown Fort Myers, this home is a renovated blast from the past. Terrazzo floors throughout kept the original Florida charm. The most peaceful neighborhood with walking distance to a restaurant with indoor/outdoor dining.
4.95 out of 5 average rating, 104 reviews
Private Hot Tub | King Bed Loft | Hammock Swings
👑 Private, fully fenced outdoor area 🦩 Hot Tub ☀️ Outdoor Patio 🌴Hammock Swings 😴 King Size Bed Loft 📶 500 Mbps+ WiFi 🥑 Kitchenette w/ electric hot plate 📚 Work Desk 📺 55-inch Smart TV + Roku ❄️ Cold A/C 🚗 1 parking space 🏡 Located on a shared property ❤️ Optional Romance Package – $89 Surprise your loved one with romantic décor, rose petals, flameless candles, balloons, chocolates, and a sparkling beverage. Message us before arrival to add it to your stay!
4.98 out of 5 average rating, 280 reviews
Modern City Loft in Downtown River District
Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.
4.99 out of 5 average rating, 104 reviewsPopular amenities for Lee County vacation rentals
Lee County apartment rentals

Prime Location w/ Private Patio + Outdoor Kitchen
4.9 out of 5 average rating, 155 reviews
Downtown Studio: Full Kitchen, King Bed, & Pool 6
4.84 out of 5 average rating, 187 reviews
Family-Ready 2BR · King + Twins · Boca Grande
4.9 out of 5 average rating, 250 reviews
Calm & Relaxing Beach Getaway!
4.92 out of 5 average rating, 169 reviews
Blackstone Villa
4.95 out of 5 average rating, 160 reviews
Resort Style Pool Adj Beds-Wilder Sunset Views!
4.93 out of 5 average rating, 135 reviews
Poolside elegance!
4.91 out of 5 average rating, 107 reviews
Villa San Carlos Park
4.94 out of 5 average rating, 157 reviewsFamily friendly vacation rentals in Lee County

Escape to the "Oasis"!
4.99 out of 5 average rating, 192 reviews
Still available for Jan, Feb, March 2027
4.9 out of 5 average rating, 161 reviews
Living on the Green
4.96 out of 5 average rating, 106 reviews
Garden Cottage - Tiny House
4.92 out of 5 average rating, 934 reviews
Flirty Flamingo Gulf Access Cape Coral Home
4.97 out of 5 average rating, 168 reviews
Bonaire Grand Luxury Villa
4.88 out of 5 average rating, 17 reviews
Luxury Riverfront Estate & Pool
4.75 out of 5 average rating, 4 reviews
6BR SW Villa - Canal Pool Retreat, putting green
4.95 out of 5 average rating, 22 reviewsFamily friendly apartments in Lee County

Vacation in Paradise
4.99 out of 5 average rating, 157 reviews
The Pearl | River Views | King | Pool+HotTub+Gym
5.0 out of 5 average rating, 14 reviews
Sundial E304: Gulf Front 3BR w/Stunning Ocean View
5.0 out of 5 average rating, 26 reviews
Amazing View of Sanibel Harbour
4.98 out of 5 average rating, 43 reviews
Marino Home II Luxury
5.0 out of 5 average rating, 11 reviews
17th Floor Riverfront • Downtown • Pool & Gym 2BR
4.96 out of 5 average rating, 45 reviews
Vista Luxe•Large Apartment•River View
4.63 out of 5 average rating, 32 reviews
Sea La Vie
4.96 out of 5 average rating, 23 reviewsDestinations to explore
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- Naples Beach
- Captiva Island
- Caspersen Beach
- Manasota Key Beach
- Englewood Beach
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- Myakka River State Park
- Florida Gulf Coast University
- Stump Pass Beach State Park
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- Barefoot beach Bonita Springs,FL
- Bonita National Golf & Country Club
- The Naples Pier
- Boca Grande Pass
- Edison & Ford Winter Estates
- Yacht Club Public Beach
- Ave Maria University
- South Jetty Beach
- Coconut Point
- Clam Pass Park
- Bunche Beach
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