
Pet-friendly vacation rentals in Lee County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Lee County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

McGregor’s Gem• Heated Pool 3BR/2BA River District
🌴 Welcome to McGregor’s Gem—your ideal Southwest Florida retreat! Dive into relaxation in your private heated pool, spread out across three bedrooms and two baths, and enjoy the perfect blend of peaceful tree-lined neighborhood living just minutes from the charming Downtown Fort Myers River District, world-class beaches, and top local attractions.☀️ Whether you’re traveling with family, friends, or on business, this home offers all the modern comforts you need for a relaxing, stress-free stay
4.96 out of 5 average rating, 148 reviews
WF Oasis~Htd Pool~Spa~Pets4Free~BBQ~Big Lanai~Dock
Step into the spacious and entertaining 3BR 2Bath nestled in a tranquil canal front area close to many restaurants, shops and attractions. Explore the city or lounge the day away under the fairy-tale tiki hut next to the swimming pool and the private dock. 🐕Pets Stay Free! ✔ 3 Comfy BRs ✔ Open Design Living ✔ Fully Equipped Kitchen ✔ Patio (Heated Pool & Spa, TV, Lounges) ✔ Yard (Tiki Hut, BBQ, Dining, Lawn) ✔ Private Dock and boats ✔ Smart TVs + PS4 + SONOS ✔ High-Speed Wi-Fi ✔ Free Parking
4.99 out of 5 average rating, 116 reviews
Elegant House 1 mile to Downtown on McGregor area
The perfect retreat at this remodeled house in quiet & safe neighborhood . 2 miles from Downtown Fort Myers's nightlife & even closer to the Skatium and City of Palms Park. Spacious living room with a 65 " smart TV connected to WIFI. Fully equipped kitchen. Studio room has independent AC, 35" TV and a Queen size pull out Sofa. The Master Bedroom has a Queen bed, a 50" TV. The 2nd bedroom has a Queen bed. Shaded wood deck with table and chairs. Gas grill. 50 Amp outlet and EV charger available.
4.88 out of 5 average rating, 111 reviews
Turtle Cove • Pool & HotTub Heat Included • Kayaks
FREE pool and hot tub heat November through March! The pool heater is set to 83°F, though water temperature may vary during cool or windy weather. Relax in the private hot tub, kayak the freshwater canal, fish from your sunset dock, grill in the outdoor kitchen or gather around the dockside fire pit. Plenty to do! Inside are 2 king bedrooms, 2 fun bunk rooms and thoughtful kid essentials. Beach chairs, umbrellas and gear are ready for close-by day trips to Fort Myers Beach, Sanibel and Matlacha.
5.0 out of 5 average rating, 6 reviews
100+ 5 Star Reviews and Right on The Beach!
We are a Superhost for a reason! Sanibel Siesta looks amazing! Immaculate beachfront, 2BR, 2BA w/garage, nicely updated beachy unit at sand's edge. Cooks kitchen. Amazing views of the Gulf w/5 star ratings! 3-day min. New hurricane windows, nicely furnished with ELEVATOR IN BUILDING! Discount for weekly/mo. rentals. BR 1:King bed ensuite, smart TV. BR 2: 2 tw. beds, smart TV. Qn. sofa bed in LR. Pool, golf course, bikes, laundry on site. No food or condiments stored in unit. May allow sm. dog.
4.95 out of 5 average rating, 121 reviews
Paradise on Estero Bay
Welcome to Mullock Creek a Boater's dream! Southwest views boasting breathtaking sunsets overlooking gulf access canal from your spacious backyard, just minutes away from shopping and dining at Coconut Point, and Gulf Coast Town Center. This stunning Key West Style home has been beautifully maintained and updated offering a lovely front entrance, fully equipped kitchen, spacious Living Room, dining room, Wi-Fi, private driveway with access to the open garage, fully furnished and private pool.
4.95 out of 5 average rating, 164 reviews
Inn Season Cottage-Cozy Florida Living
Welcome to the Inn Season Cottage...where relaxation, family time, and sunshine are always "INN" season. Experience cozy Florida living in this newly renovated 1250 sq. ft. home located in the desirable McGregor Corridor. This home is nestled within a quiet neighborhood and provides a relaxing setting for your family to unwind and make memories together. It is the ideal location for seasonal visitors looking to stay during the winter months, a small family vacation, or a couples getaway.
5.0 out of 5 average rating, 103 reviews
Heated Pool + Hot Tub |3BR | Large Pool|Sleeps 10
•Prime Location: Just minutes from Sanibel & Captiva Islands • 10-minute walk to movie theaters, shops, and restaurants • 8 min to Fort Myers • 10 min to Cape Coral Water Park • 25 min to the airport • Perfect for families & remote work • 5 Smart TVs • Fast Wi-Fi • Family-friendly amenities & games • Fully equipped kitchen • Washer & dryer • Sofa bed • Beach towels & bathrobes • Outdoor living: • BBQ grill • Outdoor dining area • FREE onsite parking • Easy self check-in
4.96 out of 5 average rating, 101 reviews
Bohemian Bungalow / Washer + Dryer / Private
Your family will be close to everything when you stay at this centrally-located place. Stylish, yet comfortable - You have access to an additional spacious sun patio, a washer and dryer, and ample back and front yard. 10 miles to the beach, biking distance to Historic Downtown Fort Myers, this home is a renovated blast from the past. Terrazzo floors throughout kept the original Florida charm. The most peaceful neighborhood with walking distance to a restaurant with indoor/outdoor dining.
4.95 out of 5 average rating, 104 reviews
Chuly |8PPL | Top Location | Hot Tub | Gazebo |BBQ
We want to Be you Host in Cape Coral! Let us show you why you should book with us: - Top Location: - 2 Min to Sun Splash Family Water Park - 20 minutos to Fort Myers Beach - 20 minutos to Sanibel Beach - New Hot Tub - 5 Smart TVs - Fast WIFI - Terrace with Gazebo - Fully equipped kitchen - Dedicated work space - Free Onsite parking - BBQ - Outside dining - Washer & Dryer - Playground - Games Room - Mini Golf - Beach towels - Residential Neighborhood - 24/7 Available Hosts
4.99 out of 5 average rating, 146 reviews
Modern City Loft in Downtown River District
Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.
4.99 out of 5 average rating, 104 reviews
Whole cozy house
Entire cozy house just for you friends and family. Perfect to spend a pleasant and relaxed moment. If you plan to have a party or event, this place is NOT for you. The neighbors are very strict in terms of noise and large groups of people. Well maintained house. CLEAN POOL BUT NOT HEATED. Walk in to a living area and separated dining. 20 minutes to airport, 25 minutes to the beach, fine dining and entertainment. For a virtual tour, click on the cover photo twice.
4.95 out of 5 average rating, 410 reviewsPopular amenities for Lee County pet-friendly home rentals
Pet-friendly house rentals

The Beachy Retreat
4.88 out of 5 average rating, 256 reviews
Blue Laguna - Vacation in paradise!
4.91 out of 5 average rating, 143 reviews
Gulf Access | Heated Pool | Spa | 2x Kings Beds
4.92 out of 5 average rating, 156 reviews
Bonita Retreat: Heated Pool - Minutes to Beach
4.99 out of 5 average rating, 151 reviews
Canalfront, Pool, Dock, Kayaks, theater, hot tub
5.0 out of 5 average rating, 3 reviews
3 bed/2 bath Saltwater Pool House Near Everything
5.0 out of 5 average rating, 26 reviews
Luxury Riverfront:Pool, Tiki Bar & Outdoor Kitchen
5.0 out of 5 average rating, 95 reviews
AquaLux Smart Home
4.91 out of 5 average rating, 91 reviewsPet-friendly home rentals with a pool

Waterfront Villa w/Pool & 2 Master King Suites
4.92 out of 5 average rating, 73 reviews
NEW!Pelican Paradise Retreat - Gulf Access
4.96 out of 5 average rating, 24 reviews
Boater’s Paradise in Bokeelia!
4.91 out of 5 average rating, 47 reviews
Swimsational Golf views
4.97 out of 5 average rating, 35 reviews
Luxury Oasis w/ Heated Pool, Theater Room & Dock!
4.97 out of 5 average rating, 33 reviews
Mediterranean Waterfront Estate on Caloosahatchee
5.0 out of 5 average rating, 8 reviews
Casa Captiva HeatedPool/GameZone/Theater/Beaches
4.95 out of 5 average rating, 38 reviews
River Views / Luxury 2BR/2BA, Pool, Walk downtown
5.0 out of 5 average rating, 15 reviewsPrivate, pet-friendly home rentals

Farm Stay at Misty Morning Farms
5.0 out of 5 average rating, 58 reviews
Bountiful Bokeelia
5.0 out of 5 average rating, 44 reviews
Waterfront Matlacha Cottage - Sunsets & Fishing!
4.93 out of 5 average rating, 60 reviews
Modern 2BR Near Sanibel & FM Beach • Sleeps 6
4.98 out of 5 average rating, 56 reviews
Designer 3BR/2BA | 5 Min to Barefoot Beach
5.0 out of 5 average rating, 7 reviews
3 BR Heated Pool House with Boat Lift
4.98 out of 5 average rating, 85 reviews
Lehigh Eden| Pool & Jacuzzi | Games | Pet friendly
5.0 out of 5 average rating, 20 reviews
Paradise House w/ Dock/Jacuzzi/Kayak/Gameroom/BBQ
5.0 out of 5 average rating, 55 reviewsDestinations to explore
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- Pet-friendly rentals Florida
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- Myakka River State Park
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